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Ekusheva E.V.

Academy of Postgraduate Education, Federal Scientific Clinical Center of the Federal Medical and Biological Agency of Russia

Dzgoeva F.Kh.

Institute for Higher and Continuing Professional Education of the National Medical Research Center for Endocrinology

Brain and obesity

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Ekusheva E.V., Dzgoeva F.Kh.

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Journal: Non Nocere. New Therapeutic Journal. 2023;(5): 28‑32

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To cite this article:

Ekusheva EV, Dzgoeva FKh. Brain and obesity. Non Nocere. New Therapeutic Journal. 2023;(5):28‑32. (In Russ.)

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What is the danger of excess body weight.

Authors:

Ekusheva E.V.

Academy of Postgraduate Education, Federal Scientific Clinical Center of the Federal Medical and Biological Agency of Russia

Dzgoeva F.Kh.

Institute for Higher and Continuing Professional Education of the National Medical Research Center for Endocrinology

List of references:

  1. Terruzzi I, Senesi P, Fermo I, Lattuada G, Luzi L. Are genetic variants of the methyl group metabolism enzymes risk factors predisposing to obesity? J Endocrinol Invest. 2007 Oct;30(9):74 7-753. https://doi.org/10.1007/BF03350812
  2. Brehm B, Gates D, Singler M, Poeppelman A, Succop P, D’Alessio D. Prevalence of obesity and cardiovascular risk factors among manufacturing company employees in Kentucky. AAOHN J. 2007 Oct;55(10):39 7-406. https://doi.org/10.1177/ 216507990705501002
  3. Lopez RP. Neighborhood risk factors for obesity. Obesity (Silver Spring). 2007;15(8):211 1-2119. https://doi.org/10.1038/oby.2007.251
  4. Davis C, Curtis C, Tweed S, Patte K. Psychological factors associated with ratings of portion size: relevance to the risk profile for obesity. Eating Behaviors. 2007;8(2):17 0-176. https://doi.org/10.1016/j.eatbeh.2006.04.002
  5. Haines J, Neumark-Sztainer D. Prevention of obesity and eating disorders: a consideration of shared risk factors. Health Education Research. 2006;21(6):77 0-782. https://doi.org/10.1093/her/cyl094
  6. Дедов И.И., Шестакова М.В., Мельниченко Г.А. с соавт. Междисциплинарные клинические рекомендации «Лечение ожирения и коморбидных заболеваний». Ожирение и метаболизм. 2021;18(1): 5-99. https://doi.org/10.14341/omet12714
  7. Тихоненко Е.В., Цой У.А., Васильева Е.Ю., Бабенко А.Ю. Характеристики пищевого поведения и уровень гормонов, регулирующих аппетит, у пациентов с сахарным диабетом 2 типа и индексом массы тела выше 35 кг/м2. Ожирение и метаболизм. 2018;15(1):3 0-38. https://doi.org/10.14341/OMET201813 0-38
  8. Leigh SJ, Morris MJ. Diet, inflammation and the gut microbiome: Mechanisms for obesity-associated cognitive impairment. Biochimica et Biophysica Acta Molecular Basis of Disease. 2020;1866(6):165767. https://doi.org/10.1016/j.bbadis.2020.165767
  9. Dye L, Boyle NB, Champ C, Lawton C. The relationship between obesity and cognitive health and decline. Proceedings of the Nutrition Society. 2017;76(4):44 3-454. https://doi.org/10.1017/S0029665117002014
  10. Yaffe K, Weston AL, Blackwell T, Krueger KA. The metabolic syndrome and development of cognitive impairment among older women. Archives of Neurology. 2009;66(3):32 4-328. https://doi.org/10.1001/archneurol.2008.566
  11. Pedditzi E, Peters R, Beckett N. The risk of overweight/obesity in mid-life and late life for the development of dementia: a systematic review and meta-analysis of longitudinal studies. Age Ageing. 2016 Jan;45(1):1 4-21. https://doi.org/10.1093/ageing/afv151
  12. Anstey KJ, Cherbuin N, Budge M, Young J. Body mass index in midlife and late-life as a risk factor for dementia: a meta-analysis of prospective studies. Obes Rev. 2011 May;12(5): e42 6-37. https://doi.org/10.1111/j.146 7-789X.2010.00825.x
  13. Hartanto A, Yong JC, Toh WX. Bidirectional Associations between Obesity and Cognitive Function in Midlife Adults: A Longitudinal Study. Nutrients. 2019 Oct 2;11(10):2343. https://doi.org/10.3390/nu11102343
  14. Kunz HE, Hart CR, Gries KJ, et al. Adipose tissue macrophage populations and inflammation are associated with systemic inflammation and insulin resistance in obesity. Am J Physiol Endocrinol Metab. 2021 Jul 1;321(1): E105–E121. https://doi.org/10.1152/ajpendo.00070.2021
  15. Raji CA, Ho AJ, Parikshak NN, et al. Brain structure and obesity. Hum Brain Mapp. 2010 Mar;31(3):35 3-364. https://doi.org/10.1002/hbm.20870
  16. Miller AA, Spencer SJ. Obesity and neuroinflammation: a pathway to cognitive impairment. Brain Behav Immun. 2014 Nov;42:1 0-21. https://doi.org/10.1016/j.bbi.2014.04.001
  17. Lowe CJ, Reichelt AC, Hall PA. The Prefrontal Cortex and Obesity: A Health Neuroscience Perspective. Trends Cogn Sci. 2019 Apr;23(4):34 9-361. https://doi.org/10.1016/j.tics.2019.01.005
  18. Khodadadi D, Gharakhanlou R, Naghdi N, et al. Treadmill Exercise Ameliorates Spatial Learning and Memory Deficits Through Improving the Clearance of Peripheral and Central Amyloid-Beta Levels. Neurochem Res. 2018 Aug;43(8):156 1-1574. https://doi.org/10.1007/s1106 4-01 8-257 1-2
  19. Prakash RS, Voss MW, Erickson KI, Kramer AF. Physical activity and cognitive vitality. Annu Rev Psychol. 2015 Jan 3;66:76 9-797. https://doi.org/10.1146/annurev-psych-01081 4-015249
  20. Alkadhi KA. Exercise as a Positive Modulator of Brain Function. Mol Neurobiol. 2018 Apr;55(4):311 2-3130. https://doi.org/10.1007/s1203 5-01 7-051 6-4
  21. Fungwe TV, Ngwa JS, Ntekim OE, et al. Exercise Training Induced Changes In Nuclear Magnetic Resonance-Measured Lipid Particles In Mild Cognitively Impaired Elderly African American Volunteers: A Pilot Study. Clin Interv Aging. 2019 Dec 5;14:211 5-2123. https://doi.org/10.2147/CIA.S195878

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