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Yashina L.N.

State Research Center of Virology and Biotechnology “VECTOR” of Rospotrebnadzor

Zinich L.S.

Anti-plague Station of the Republic of Crimea

Smetannikova N.A.

State Research Center of Virology and Biotechnology “VECTOR” of Rospotrebnadzor

Kartashov M.Yu.

State Research Center of Virology and Biotechnology “VECTOR” of Rospotrebnadzor

Kovalenko I.S.

Anti-plague Station of the Republic of Crimea

Yusupova Z.S.

Anti-plague Station of the Republic of Crimea

Konashenko E.V.

Anti-plague Station of the Republic of Crimea

Tikhonov S.N.

Anti-plague Station of the Republic of Crimea

Hantaviruses (Hantaviridae) in Republic of Crimea

Authors:

Yashina L.N., Zinich L.S., Smetannikova N.A., Kartashov M.Yu., Kovalenko I.S., Yusupova Z.S., Konashenko E.V., Tikhonov S.N.

More about the authors

Journal: Molecular Genetics, Microbiology and Virology. 2024;42(4): 37‑42

DOI: 10.17116/molgen20244204137

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Table of contents

HANTAVIRUSES (HANTAVIRIDAE) IN REPUBLIC OF CRIMEA
HANTAVIRUSES (HANTAVIRIDAE) IN REPUBLIC OF CRIMEA

To cite this article:

Yashina LN, Zinich LS, Smetannikova NA, et al. . Hantaviruses (Hantaviridae) in Republic of Crimea. Molecular Genetics, Microbiology and Virology. 2024;42(4):37‑42. (In Russ.)
https://doi.org/10.17116/molgen20244204137

Подписка 2026 Молекулярная генетика, микробиология и вирусология (Molecular Genetics, Microbiology and Virology)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
Abstract:

Hantaviruses (family Hantaviridae), widely distributed in various regions of the world, are important zoonotic pathogens of humans. Studies of the geographical distribution, species diversity of hantaviruses and their natural hosts have identified numerous species of hantaviruses among rodents, insectivores and chiropterans.

Goal of the work. Genetic identification study of hantaviruses circulating in the territory of the Republic of Crimea.

THE GOAL OF THE STUDY

Was the genetic identification of hantaviruses in the Republic of Crimea.

MATERIALS AND METHODS

Lung tissue samples from 119 voles of the genus Microtus, 66 mice of the genus Sylvaemus and 28 insectivores of the genus Crocidura, captured in the Republic of Crimea in 2021—2023, were tested for hantavirus antigen by an antigen-capture ELISA and/or reverse transcription-polymerase chain reaction, followed by phylogenetic analysis.

RESULTS

Hantavirus RNA was detected in three species of animals: the common vole (Microtus arvalis form obscurus), the social vole (Microtus socialis) and the lesser white-toothed shrew (Crocidura suaveolens). Phylogenetic analysis of the L- and S-segments sequences of the genome showed that two different genetic variants of the Tula virus were found in the common vole and the social vole. The hantavirus associated with Crocidura suaveolens, was designated Artesian virus (ATSV) and was a putative new species phylogenetically related to hantaviruses circulating among insectivores of the genus Crocidura in Africa.

CONCLUSION

The pathogenic potential of the identified hantaviruses has not been studied, but it was previously established that phylogenetically related viruses can infect humans.

Keywords:

hantavirus
voles
insectivores
phylogenetic analysis
Republic of Crimea

Authors:

Yashina L.N.

State Research Center of Virology and Biotechnology “VECTOR” of Rospotrebnadzor

Zinich L.S.

Anti-plague Station of the Republic of Crimea

Smetannikova N.A.

State Research Center of Virology and Biotechnology “VECTOR” of Rospotrebnadzor

Kartashov M.Yu.

State Research Center of Virology and Biotechnology “VECTOR” of Rospotrebnadzor

Kovalenko I.S.

Anti-plague Station of the Republic of Crimea

Yusupova Z.S.

Anti-plague Station of the Republic of Crimea

Konashenko E.V.

Anti-plague Station of the Republic of Crimea

Tikhonov S.N.

Anti-plague Station of the Republic of Crimea

Received:

02.09.2024

Accepted:

24.09.2024

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