Mixed etiology of inflammatory diseases of the urinary tract in women is presented not only by different combinations of obligate pathogens, but also by representatives of normal microbiota of the vagina, in particular yeast-like fungi of the Candida spp. genus.
OBJECTIVE
To study clinical, anamnestic and laboratory data of patients with genitourinary candidiasis (GUC) in combination with sexually transmitted infections (STIs) and/or genitourinary diseases associated with M. hominis, U. parvum, U. urealyticum.
MATERIAL AND METHODS
The study included 133 patients aged between 18 and 67 years, who were treated in the Outpatient Department No. 1 of the Novosibirsk Regional Clinical Dermatovenerologic Dispensary.
RESULTS
A concomitant GUC has been noted in 29 (28.4%) of all patients diagnosed with STIs and/or genitourinary diseases associated with M. hominis, U. parvum, U. Urealyticum. GUC in association with genitourinary trichomoniasis has been revealed in 10 (34.5%) patients, with U. parvum — in 8 (27.5%) and with U. urealyticum — in 3 (10.3%). Genitourinary trichomoniasis was most commonly diagnosed (19/33.3%) as monoinfection, and combinations of C. Trachomatis + U. Parvum + M. hominis (4/25%) were more common among mixed infections represented by obligate pathogens, as well as T. Vaginalis + U. parvum and M. Hominis + U. Parvum + U. Urealyticum — 2 (25%) cases of each.
CONCLUSION
The combination of GUC with obligate pathogens was identified in more than 25% of patients who have made an appointment with dermatovenerologist. A combination of Candida spp. infection with T. vaginalis, U. parvum and U. urealyticum has been found in more than half of STIs cases. During the physical examination clinical signs of vaginitis and cervicitis were mostly observed, less often — urethritis.