Squamous cell carcinoma of the vulva in dermatovenerologist practice: a clinical case

Ziganshin OR, Letyaeva OI, Kazachkov EL, et al. . Squamous cell carcinoma of the vulva in dermatovenerologist practice: a clinical case. Russian Journal of Clinical Dermatology and Venereology. 2023;22(3):281‑286. (In Russ.)
https://doi.org/10.17116/klinderma202322031281

Подписка 2025-2 (Russian Journal of Clinical Dermatology and Venereology)

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A rare squamous cell carcinoma of the vulva in a patient of reproductive age diagnosed by a dermatovenerologist is presented. The risk factors, epidemiology, mechanisms of vulvar carcinoma development, and etiological and pathogenetic features of tumors in persons of reproductive age are addressed. The dermatovenerologist evaluated the history, clinical, and objective examination data, diagnosed the «neoplasm of the vulva», and referred the patient to a special screening examination for sexually transmitted infections that showed types 16 and 18 HPV. The patient was referred to an oncological hospital, where the diagnosis was morphologically verified: squamous keratinizing carcinoma of the vulva. Neoadjuvant polychemotherapy, vulvectomy, and Ducuing surgery on the left side were performed sequentially. Considering the diagnostic, therapeutic measures and analysis of the data obtained, the following diagnosis was made: C51.8. Vulvar cancer, stage III (T2N1M0) after neoadjuvant polychemotherapy (100% tumor resorption) and two stages of surgical treatment (vulvectomy, Ducuing operation on the left side). This case is intended to draw the attention of dermatovenerologists to the issue of vulvar carcinoma in patients of reproductive age, contributing to its early diagnosis in women and timely treatment.

Keywords:

vulvar carcinoma

patient’s reproductive age

dermatovenerology practice

Authors:

Ziganshin O.R.

South Ural State Medical University

ORCID: 0000-0002-5857-0319

Letyaeva O.I.

South Ural State Medical University

ORCID: 0000-0002-9085-6229

Kazachkov E.L.

South Ural State Medical University

ORCID: 0000-0002-4512-3421

Voropaeva A.I.

South Ural State Medical University

ORCID: 0000-0002-5368-1458

Kazachkova E.A.

South Ural State Medical University

ORCID: 0000-0002-1672-7058

Shamanova A.Yu.

Chelyabinsk Regional Clinical Center for Oncology and Nuclear Medicine;
South Ural State Medical University of the Ministry of Health of Russia

ORCID: 0000-0002-9280-0608

Saevets V.V.

Chelyabinsk Regional Clinical Center for Oncology and Nuclear Medicine;
South Ural State Medical University of the Ministry of Health of Russia

ORCID: 0000-0003-2572-2408

Sirazetdinov A.R.

South Ural State Medical University

ORCID: 0000-0002-4969-0618

Received:

28.12.2023

Accepted:

19.04.2023

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