The relevance of the topic is due to the increase in recent years the proportion of latent and late forms of syphilis, as well as accumulation in the general population of HIV patients. Both infections can cause pathology of the cardiovascular system (CVS) that confirms the need to inform dermatovenerologists and infectious disease specialists about this pathology.

OBJECTIVE

To compare the frequency and nature of pathological changes in CVS in patients with late forms of syphilis and late stages of HIV infection.

MATERIAL AND METHODS

A CVS examination (ECG, echo-CG, Doppler ultrasound of the brachiocephalic arteries) was performed in patients of 3 groups: 1) 120 persons with late latent syphilis or syphilis in the past; 2) 43 patients with HIV infection at stages 3, 4A, 4B and 4C; 3) 40 conditionally healthy persons who underwent periodic medical examination (control group).

RESULTS AND DISCUSSION

In the 1^st group, CVS pathology characteristic of syphilis (aortitis, aortic valvulitis, myocarditis) was detected in 12 (10%) patients. In 2^d group, pathology typical for HIV infection (infective endocarditis, pericarditis, pulmonary hypertension) was found in 17 (40%) patients. In the 3^rd (control) group, changes characteristic of atherosclerosis was detected in 3 (7.5%) patients.

CONCLUSION

In patients with late forms of syphilis and late stages of HIV infection there was a high incidence of CVS pathology (10% and 40%, respectively) with manifestations typical for each of these infections. The dependence of the CVS pathology on the stage of HIV infection, the use of psychoactive substances, the presence of concomitant infections is indicated.