A promising direction in the post-procedural care of the skin and mucous membranes after the destruction of neoplasms is the use of medicines with anti-adhesive properties that prevent the adhesion and reproduction of microorganisms on the damaged epithelium and contribute to the fast tissues epithelialization.

OBJECTIVE

Effectiveness evaluation of the medical cooling hydrogel usage which contains natural anti-adhesive polysaccharides (2QR-complex) in post-procedural care after the skin and mucous membranes’ neoplasms destruction.

MATERIAL AND METHODS

Patients with neoplasms of the skin and mucous membranes after radio-wave (subgroup A) or chemical (subgroup B) destruction: patients of group 1 (n=25) after destruction used a medical cooling hydrogel containing a complex of natural antiadhesive polysaccharides (2QR-complex), patients of group 2 (n=27) did not use any drug therapy. Patients were followed up for 7—10 days after destruction.

RESULTS

The severity of itching and pain on the 1^st and 2^nd day after destruction in patients of the 1^st A subgroup were 2 and 1.7 points on averaged, the 1^st B subgroup — 2.2 and 2 points, the 2^nd A subgroup — 4.2 and 5.2 points, 2^nd B subgroup — 4.5 and 5.2 points. The complete absence of subjective symptoms in patients of the 1^st group was registered on the 4^th day of therapy, in the 2^nd group — on the 6—7^th day. Epithelialization of the wound surface in 92.3% of patients in the 1^st group was recorded on the 5^th day of observation, in 88.8% of patients in the 2^nd group — on the 7—10^th day. Pathological discharge from the wound surface during the entire observation period was completely absent in patients of the 1^st group, and in patients of the 2^nd group the presence of serous (40.7%) and serous-purulent wound discharge (18.5%) was established.

CONCLUSION

The use of a medical cooling hydrogel containing a complex of natural antiadhesive polysaccharides (2QR-complex) in patients after destruction of neoplasms has demonstrated optimal therapeutic efficacy which makes it possible to recommend it in post-procedural care in order to accelerate the regeneration of epithelial tissues and prevent secondary infection.