Clinical observations of pigment xerodermia in the poikilodermic stage in a young man, M., 17 years old, and a girl Z., 7 years old, and an abortive form — Jung’s pigmented xerodermoid — in a woman, 47 years old, are presented. The young man noted the deformation and constriction of the oral opening: numerous cracks, dryness and atrophic cicatricial changes. Pronounced tooth decay. The eyes are affected on both sides. The girl noted the itching of the affected areas — the forearms, the back of the hands and feet, where small warty growths were found. As a result of therapy, the clinical status in the patients remained unchanged; only the girl’s itching became less pronounced. The manifestations of Jung’s pigmented xerodermoid developed in an interesting way. The patient’s face, neck, and oral mucosa were affected from birth. Over time, the exanthema changed brightness, and shifted somewhat. The rash did not cause any subjective sensations. One year ago, warts appeared on the affected areas; 3 months ago, the visual acuity of the left eye deteriorated and there was a noise in the left ear. In bright sunlight, there was “rippled” vision in the left eye, and then there was a buzz and pain in the head. The lesion of the skin had a maroon color, sometimes purple and dark red with areas of healthy skin. The skin of the chin and lower lip were hypertrophied and infiltrated. Observed areas of healthy skin. The hair on the left eyebrow and scalp, and vellus hair in the lesion were preserved. In the pigmented area, warts and blackheads were identified in places. The left half of the oral mucosa and tongue had a saturated red color strictly to the midline. The infiltration of the affected half of the tongue was noted.