On the differential diagnosis of the palmoplantar hyperkeratotic dermatoses

Isaeva D.R.; Khaldin A.A.

doi:https://doi.org/10.17116/klinderma2016156120-126

Isaeva D.R.

Moskovskiĭ nauchno-prakticheskiĭ tsentr dermatovenerologii i kosmetologii Departamenta zdravookhraneniia, Moskva, 119071, Rossiĭskaia Federatsiia;
Tsentr virusnoĭ patologii kozhi, Moskva, 129226, Rossiĭskaia Federatsiia

Khaldin A.A.

Nekommercheskoe partnerstvo "GERPES-FORUM";
Moskovskiĭ nauchno-prakticheskiĭ Tsentr dermatovenerologii i kosmetologii Departamenta zdravookhraneniia Moskvy

On the differential diagnosis of the palmoplantar hyperkeratotic dermatoses

Authors:

Isaeva D.R., Khaldin A.A.

More about the authors

Journal: Russian Journal of Clinical Dermatology and Venereology. 2016;15(6): 120‑126

DOI: 10.17116/klinderma2016156120-126

Read: 4368 times

Download PDF (RU)

Contact the author

Table of contents

To cite this article:

Isaeva DR, Khaldin AA. On the differential diagnosis of the palmoplantar hyperkeratotic dermatoses. Russian Journal of Clinical Dermatology and Venereology. 2016;15(6):120‑126. (In Russ.)
https://doi.org/10.17116/klinderma2016156120-126

Подписка 2026 Клиническая дерматология и венерология (Russian Journal of Clinical Dermatology and Venereology)

Использование инфографики авторами научных работ

Close metadata

Recommended articles:

Descriptive epidemiological study of the morbidity with hereditary non-syndromic disorders of keratinization among the population of Moscow. Russian Journal of Clinical Dermatology and Venereology. 2025;(6):750-759

A familial case of Bothnian palmoplantar keratoderma caused by the c.103T>G substitution in the AQP5 gene. Russian Journal of Clinical Dermatology and Venereology. 2025;(6):765-768

Abstract:

The article reports the results of clinical observation of the patients with focal palmoplantar keratoderma and porokeratosis. The article describes the clinical and histopathological characteristics of the focal keratoderma and porokeratosis. Special attention was paid to the peculiarities of the clinical course of the diseases in question and the differential diagnosis with palmoplantar warts.

Keywords:

palmoplantar keratoderma

porokeratosis

palmoplantar warts

Authors:

Isaeva D.R.

Khaldin A.A.

Nekommercheskoe partnerstvo "GERPES-FORUM";
Moskovskiĭ nauchno-prakticheskiĭ Tsentr dermatovenerologii i kosmetologii Departamenta zdravookhraneniia Moskvy

Close metadata

References:

OL Ivanov. Kozhnye i venericheskie bolezni. Shiko, St. Peterburg 2006. (In Russ)
Mordovtsev VN, Butov YuS, Mordovtseva VV. Rukovodstvo dlya vrachey: Klinicheskaya dermatovenerologiya. Moscow, 2009. (In Russ)
Akimov VG. Hereditary and acquired palmoplantar keratoderma. Consilium Medicum (annex Dermatology), 2011:3. (In Russ)
Pototskiy II. Giperkeratozy. Kiev, 1977. (In Russ)
Tomas P Khebif. Kozhnye bolezni. Diagnostika i lechenie. Moscow: MEDpress-inform, 2006. (In Russ)
LS Kruglova, OV Zhukova, EI Fineshina. Pathogenetic aspects underlying palmoplantar keratoderma. Current therapies. Klinicheskaya dermatologiya i venerologiya, 2015:2. (In Russ)
Pal'tsev MA, Potekaev NN. Kliniko-morfologicheskaya diagnostika zabolevaniy kozhi. Moscow, 2004. (In Russ)
Itin PH, Fistarol SK. Palmoplantar keratodermas. Clin. Dermatol. 2005; v. 23, No 1:15–22.
Miljković J, Kansky A. Hereditary palmoplantar keratoderma type papulosa in Slovenia. Acta dermatovenerologica Alpina, Pannonica, Adriat. 2009; v. 18, No 3:114–116.
Herranz P et al. High incidence of porokeratosis in renal transplant recipients. Br. J. Dermatol, 1997;v. 136, No 2: 176–179.
Alexis AF, Busam K, Myskowski PL. Porokeratosis of Mibelli following bone marrow transplantation. Int. J. Dermatol, 2006:v. 45, No 4:361–5.5.
Bae JM et al. Differential diagnosis of plantar wart from corn, callus and healed wart with the aid of dermoscopy. Br. J. Dermatol, 2009;v. 160, No 1:220–222.
AA Khaldin et al. The case of Buschke-Fischer focal keratoderma. Rossiyskiy zhurnal kozhnykh i venericheskikh bolezney, 2008:2. (In Russ)
K Wolff, LA Goldsmith, Katz SI, et al. Fitzpatrick's Dermatology in Clinical Medicine; translated from English; under the general editorship of acad. AA Kubanova, 2013. (In Russ)
Hennies HC et al. Keratin 9 gene mutational heterogeneity in patients with epidermolytic palmoplantar keratoderma. Hum. Genet, 1994:v. 93, No 6:649–654.
Liu W-T et al. The most common mutation of KRT9, c.C487T (p.R163W), in epidermolytic palmoplantar keratoderma in two large Chinese pedigrees. Anat. Rec. (Hoboken), 2012:v. 295, No 4: 604–609.
Lai Cheong JE, Wessagowit V, McGrath JA. Molecular abnormalities of the desmosomal protein desmoplakin in human disease. Clin. Exp. Dermatol, 2005;v. 30, No 3: 261–6.6. Cao Y-A et al. Gene expression profiling in pachyonychia congenita skin. J. Dermatol. Sci., 2015;v. 77, No 3:156–165.
McGrath JA. Inherited disorders of desmosomes. Australas. J. Dermatol., 2005;v. 46, No 4:221–229.
Pigors M et al. Desmoplakin mutations with palmoplantar keratoderma, woolly hair and cardiomyopathy. Acta Derm. Venereol., 2015;v. 95, No 3:337–340.
Whittock NV et al. Frameshift mutation in the V2 domain of human keratin 1 results in striate palmoplantar keratoderma. J. Invest. Dermatol., 2002;v. 118, No 5:838–844.
Cao Y-A et al. Gene expression profiling in pachyonychia congenita skin. J. Dermatol. Sci., 2015; 77, No 3:156–65.7.
Liao H et al. A spectrum of mutations in keratins K6a, K16 and K17 causing pachyonychia congenita. J. Dermatol. Sci., 2007;v. 48, No 3:199–205.
Myadelets OD, Adaskevich VP. Funktsional'naya morfologiya i obshchaya patologiya kozhi. Vitebsk: Publishing house of the Vitebsk Medical Institute, 1997. (In Russ)
Kozhnye i venericheskie bolezni. Rukovodstvo dlya vrachey. Ed by YuK Skripkin, VN Mordovtsev. Moscow: Meditsina, 1999. (In Russ)
El'kin VD, Mitrokovskiy LS, Sedova TG. Izbrannaya dermatologiya. Redkie dermatozy i dermatologicheskie sindromy: 2nd edition. Perm', 2004. (In Russ)
Marque M, Meunier L. [Porokeratosis]. Ann. dermatologie vénéréologie, 2012;v. 139, No 10:668–676.
Irisawa R et al. A case of porokeratosis plantaris palmaris et disseminata and literature review. Dermatol. Online J. 2012;v. 18, No 8: 5.
Shumack S, Commens C, Kossard S. Disseminated superficial actinic porokeratosis. A histological review of 61 cases with particular reference to lymphocytic inflammation. Am. J. Dermatopathol. 1991;. 13, No 1:26–31.
Zhao M et al. Porokeratosis with follicular involvement: report of three cases and review of literatures. Int. J. Clin. Exp. Pathol. 2015;v. 8, No 4:4248–52.32.
Zhang Z et al. Fine mapping and identification of a candidate gene SSH1 in disseminated superficial actinic porokeratosis. Hum. Mutat. 2004;v. 24, No 5:438.
Zhang ZH et al. A mutation in SART3 gene in a Chinese pedigree with disseminated superficial actinic porokeratosis. Br. J. Dermatol. 2005;v. 152, No 4:658–663.
Gu C-Y et al. Clinical analysis and etiology of porokeratosis. Exp. Ther. Med. 2014;v. 8, No 3:737–741.
L'vov DK. Meditsinskaya virusologiya. Moscow: MIA, 2008. (In Russ)
Molochkov VA, Molochkov AV, Khlebnikova AN, Kuntsevich ZhS. Epitelial'nye opukholi kozhi. Moscow: Binom, 2012. (In Russ)
Watkins P. Identifying and treating plantar warts. Nurs. Stand. 2006;v. 20. No 42:50–54.
Wortsman X, Jemec GBE, Sazunic I. Anatomical detection of inflammatory changes associated with plantar warts by ultrasound. Dermatology, 2010;v. 220, No 3:213–217.
Wortsman X, Sazunic I, Jemec GBE. Sonography of plantar warts: role in diagnosis and treatment. J. Ultrasound Med. 2009;28, No 6:787–793.