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Tseimakh A.E.

Altai State Medical University

Shoikhet Ya.N.

Altai State Medical University

Pantyushin A.A.

Clinic Hospital “Russian Railway-Medicine”

Saxena I.

Altai State Medical University

Prevention of recurrent laryngeal nerve injury in thyroid surgery: a systematic review and meta-analysis

Authors:

Tseimakh A.E., Shoikhet Ya.N., Pantyushin A.A., Saxena I.

More about the authors

Journal: Pirogov Russian Journal of Surgery. 2025;(3): 140‑148

DOI: 10.17116/hirurgia2025031140

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Table of contents

PREVENTION OF RECURRENT LARYNGEAL NERVE INJURY IN THYROID SURGERY: A SYSTEMATIC REVIEW AND META-ANALYSIS
PREVENTION OF RECURRENT LARYNGEAL NERVE INJURY IN THYROID SURGERY: A SYSTEMATIC REVIEW AND META-ANALYSIS

To cite this article:

Tseimakh AE, Shoikhet YaN, Pantyushin AA, Saxena I. Prevention of recurrent laryngeal nerve injury in thyroid surgery: a systematic review and meta-analysis. Pirogov Russian Journal of Surgery. 2025;(3):140‑148. (In Russ.)
https://doi.org/10.17116/hirurgia2025031140

Подписка 2026 Хирургия. Журнал им. Н.И. Пирогова (Pirogov Russian Journal of Surgery)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

OBJECTIVE

To evaluate the effectiveness of modern methods for preventing damage to recurrent laryngeal nerve in thyroid surgery.

MATERIAL AND METHODS

Full-text prospective comparative studies were reviewed in the PubMed Central databases, bibliographic database of the Russian Science Citation Index and Cochrane library database. Heterogeneity was assessed using forest plots, tau2 and I2 statistics.

RESULTS

Meta-analysis of pooled risk of recurrent laryngeal nerve injuries revealed significantly lower pooled estimate of the incidence of recurrent laryngeal nerve injuries in groups of intraoperative neuromonitoring (z=–2.04, p=0.0409). Heterogeneity among studies was not significant (I2=28%, p=0.25). Meta-analysis of pooled risk of damage to recurrent laryngeal nerve in case of prevention by precise dissection using ultrasound and electric cauterization found no significant differences in both groups (z= –0.19, p=0.8806). Heterogeneity among studies was moderate (I2=60%, p=0.11). There were no significant publication biases.

CONCLUSION

Intraoperative neuromonitoring and precise dissection of recurrent laryngeal nerve using ultrasound and electric cauterization reduce surgery time. Intraoperative neuromonitoring is advisable as an optional procedure for prevention of damage to recurrent laryngeal nerve.

Keywords:

recurrent laryngeal nerve injury
meta-analysis
thyroid gland

Authors:

Tseimakh A.E.

Altai State Medical University

Shoikhet Ya.N.

Altai State Medical University

Pantyushin A.A.

Clinic Hospital “Russian Railway-Medicine”

Saxena I.

Altai State Medical University

Received:

21.05.2024

Accepted:

29.07.2024

Close metadata

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