The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-4329
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2026
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Rudenko M.S.

Ural State Medical University;
Sverdlovsk Regional Oncology Dispensary

Pushkin S.Yu.

Seredavin Samara Regional Clinical Hospital;
Samara State Medical University

Toneev E.A.

Regional Clinical Oncology Center;
Ulyanovsk State University

Shagdaleev R.F.

Regional Clinical Oncology Dispensary;
Ulyanovsk State University

Kamenev R.O.

Ural State Medical University

Kiselev E.A.

Ural State Medical University;
Sverdlovsk Regional Oncology Dispensary

Biryukov D.V.

Ulyanovsk State University

Sharkaev A.T.

Ulyanovsk State University

Prediction of respiratory complications after extensive chest wall resections

Authors:

Rudenko M.S., Pushkin S.Yu., Toneev E.A., Shagdaleev R.F., Kamenev R.O., Kiselev E.A., Biryukov D.V., Sharkaev A.T.

More about the authors

Journal: Pirogov Russian Journal of Surgery. 2025;(12): 14‑22

DOI: 10.17116/hirurgia202512114

Read: 480 times

Buy for 300₽
Contact the author
Table of contents

PREDICTION OF RESPIRATORY COMPLICATIONS AFTER EXTENSIVE CHEST WALL RESECTIONS
PREDICTION OF RESPIRATORY COMPLICATIONS AFTER EXTENSIVE CHEST WALL RESECTIONS

To cite this article:

Rudenko MS, Pushkin SYu, Toneev EA, et al. Prediction of respiratory complications after extensive chest wall resections. Pirogov Russian Journal of Surgery. 2025;(12):14‑22. (In Russ.)
https://doi.org/10.17116/hirurgia202512114

 
Подписка 2026 Хирургия. Журнал им. Н.И. Пирогова (Pirogov Russian Journal of Surgery)
МСФ на ЯМ
Использование инфографики авторами научных работ
Recommended articles:
Model for predicting mortality in patients with traumatic brain injury. Russian Journal of Anesthesiology and Reanimatology. 2025;(5):66-73
Abstract:

OBJECTIVE

To analyze the incidence of respiratory complications following chest wall surgeries with reconstructive approaches and to develop a nomogram for predicting complication risk.

MATERIAL AND METHODS

From 2013 to 2024, a multicenter ambispective study was conducted including 125 patients who underwent chest wall resection for various indications.

RESULTS

The rate of respiratory complications after chest wall resection was 15.2%. Logistic regression analysis identified three independent prognostic factors: intraoperative blood loss (OR=1.006), number of resected ribs (OR=1.561), and FEV1 level (OR=0.935; reciprocal OR=1.069), highlighting their contribution to complication risk. The regression model was statistically significant (p<0.001) and demonstrated high discriminatory ability. The area under the ROC curve was 0.895±0.049 (95% CI 0.798—0.992), with sensitivity of 94.7% and specificity of 78.3%. The optimal cut-off value based on the Youden index was 0.138, above which the risk of respiratory complications was considered high. Nagelkerke’s pseudo-R² was 78.1%, indicating strong explanatory power. Based on these results, a nomogram was developed using machine learning methods to predict respiratory complication risk. Validation confirmed the model’s reliability and clinical applicability for individualized risk assessment.

CONCLUSION

This study identified blood loss, number of resected ribs, and FEV1 as key prognostic factors for respiratory complications after chest wall reconstruction. A predictive nomogram based on logistic regression was developed for clinical use.

Keywords:

chest wall reconstruction
nomogram
respiratory complications
Codubix

Authors:

Rudenko M.S.

Ural State Medical University;
Sverdlovsk Regional Oncology Dispensary

Pushkin S.Yu.

Seredavin Samara Regional Clinical Hospital;
Samara State Medical University

Toneev E.A.

Regional Clinical Oncology Center;
Ulyanovsk State University

Shagdaleev R.F.

Regional Clinical Oncology Dispensary;
Ulyanovsk State University

Kamenev R.O.

Ural State Medical University

Kiselev E.A.

Ural State Medical University;
Sverdlovsk Regional Oncology Dispensary

Biryukov D.V.

Ulyanovsk State University

Sharkaev A.T.

Ulyanovsk State University

Received:

24.03.2025

Accepted:

16.05.2025

Close metadata

References:

  1. Jo, Gang Yeon, Sae Hwi Ki. Analysis of the Chest Wall Reconstruction Methods after Malignant Tumor Resection. Arch Plastic Surg. 2023;50(1):10-16.  https://doi.org/10.1055/s-0042-1760290
  2. Rudenko MS, Kamenev RO, Gusev DA, Eliseeva AP. Reconstruction of the Chest Wall During Extensive Resections. Literature Review. Own Experience. Ural Medical Journal. 2024;23(4):57-76. (In Russ.). https://doi.org/10.52420/umj.23.4.57
  3. Pikin OV, Ryabov AB, Alexandrov OA, et al. Chest wall reconstruction with a non-rigid synthetic rib prosthesis: a multicenter study. Pirogov Russian Journal of Surgery. 2024;8:41-51. (In Russ.). https://doi.org/10.17116/hirurgia202408141
  4. Asanuma K, Tsujii M, Hagi T, Nakamura T, Kita K, Shimamoto A, Kataoka T, Takao M and Sudo A. Full-thickness chest wall resection for malignant chest wall tumors and postoperative problems. Front Oncol. 2023;13:1104536. https://doi.org/10.3389/fonc.2023.1104536
  5. Rudenko MS, Pushkin SYu, Magdalyanova MI, Kamenev RO, Eliseeva AP, Gusev DA. Chest wall repair after extensive resections. Pirogov Russian Journal of Surgery. 2023;10:60-70. (In Russ.). https://doi.org/10.17116/hirurgia202310160
  6. Toneev EA, Komarov AS, Midlenko OV, Martynov AA, Isaev DN, Chavkin PM. Predictive models for assessing risks postoperative cardiac and respiratory complications in patients with lung cancer. Ul’yanovskij mediko-biologicheskij zhurnal. 2024;1:41-63. (In Russ.). https://doi.org/10.34014/2227-1848-2024-1-41-63
  7. Lampridis S, Minervini F, Scarci M. Management of complications after chest wall resection and reconstruction: a narrative review. J Thorac Dis. 2024;16(1):737-749.  https://doi.org/10.21037/jtd-23-621
  8. Hayashi T, Sakakura N, Ishimura D, Kozawa E, Yoshida M, Sakao Y, Yamada H, Tsukushi S. Surgical complication and postoperative pulmonary function in patients undergoing tumor surgery with thoracic wall resection. Oncology Letters. 2019;17(3):3446-3456. https://doi.org/10.3892/ol.2019.9997
  9. de Macedo JPC, Nabuco-de-Araujo PHX, Bibas BJ, de Campos JRM, Pêgo-Fernandes PM, Terra RM. Predictors of postoperative complications after sternectomy on oncologic patients. Clinics (Sao Paulo, Brazil). 2024;79:100468. https://doi.org/10.1016/j.clinsp.2024.100468
  10. Nayak R, Choe SI, Shargall Y. Complications of Chest Wall Resection in Conjunction with Pulmonary Resection. Thorac Surg Clin. 2021; 31(4):393-398.  https://doi.org/10.1016/j.thorsurg.2021.07.010
  11. Young JS, McAllister M, Marshall MB. Three-dimensional technologies in chest wall resection and reconstruction. J Surg Oncol. 2023; 127(2):336-342.  https://doi.org/10.1002/jso.27164
  12. Yao L, Wang W. Effect of intraoperative blood loss on postoperative pulmonary complications in patients undergoing video-assisted thoracoscopic surgery. Turk Gogus Kalp Dama. 2021;29:347-353.  https://doi.org/10.5606/tgkdc.dergisi.2021.20657
  13. Scarnecchia E, Liparulo V, Capozzi R, Ceccarelli S, Puma F, Vannucci J. Chest wall resection and reconstruction for tumors: analysis of oncological and functional outcome. J Thorac Dis. 2018;10(Suppl 16):S1855-S1863. https://doi.org/10.21037/jtd.2018.05.191
  14. Wang L, Yan X, Zhao J, Chen C, Chen C, Chen J, Chen KN, Cao T, Chen MW, Duan H, Fan J, Fu J, Gao S, Guo H, Guo S, Guo W, Han Y, Jiang GN, Jiang H, Jiao WJ. Expert consensus on resection of chest wall tumors and chest wall reconstruction. Translat Lung Cancer Res. 2021;10(11):4057-4083. https://doi.org/10.21037/tlcr-21-935
  15. Toneev EA, Komarov AS, Midlenko OV, Golovatyukov AV, Isaev DN. Multidisciplinary Prehabilitation in Planning Lobectomy: A Randomized Clinical Study. Modern Problems of Science and Education. 2024;1. (In Russ.). https://doi.org/10.17513/spno.33265
  16. Weyant MJ, Bains MS, Venkatraman E, Downey RJ, Park BJ, Flores RM, Rizk N, Rusch VW. Results of chest wall resection and reconstruction with and without rigid prosthesis. Ann Thorac Surg. 2006; 81(1):279-285.  https://doi.org/10.1016/j.athoracsur.2005.07.001
  17. Dharmaraj B, Diong NC, Shamugam N, Sathiamurthy N, Mohd Zainal H, Chai SC, Koh KL, Mat Zain MA, Haji Basiron N. Chest wall resection and reconstruction: a case series of 20 patients in Hospital Kuala Lumpur, Malaysia. Indian J Thorac Cardiovasc Surg. 2021;37(1):82-88.  https://doi.org/10.1007/s12055-020-00972-7
  18. Topolnitskiy EB, Shefer NA, Marchenko ES, Chekalkin TL, Khakimov KhI. Reconstruction of post-resection chest wall defects in surgical treatment of invasive non-small cell lung cancer. Pirogov Russian Journal of Surgery. 2022;(12):31-40. (In Russ.). https://doi.org/10.17116/hirurgia202212131
  19. Forster C, Jacques V, Abdelnour-Berchtold E, Krueger T, Perentes JY, Zellweger M, Gonzalez M. Enhanced recovery after chest wall resection and reconstruction: a clinical practice review. J Thorac Dis. 2024;16(4):2604-2612. https://doi.org/10.21037/jtd-23-911
  20. Anisenya II, Topolnitskiy EB, Khakimov KhI, Bogoutdinova AV, Sitnikov PK. Successful reconstruction of the chest wall frame with superelastic nickel-titanium 3D modules in a patient with multiple locally recurrent leiomyosarcoma. Bone and Soft Tissue Sarcomas, Tumors of the Skin. 2022;14(2):44-51. (In Russ.). https://doi.org/10.17650/2782-3687-2022-14-2-44-51
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.