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Tarasova I.A.

Petrovsky National Research Centre of Surgery;
Sechenov First Moscow State Medical University (Sechenov University)

Tshkovrebov A.T.

Petrovsky National Research Centre of Surgery

Bitarov T.T.

Petrovsky National Research Centre of Surgery

Boeva I.A.

Petrovsky National Research Centre of Surgery

Ivanova M.Yu.

Sechenov First Moscow State Medical University (Sechenov University)

Shestakov A.L.

Petrovsky National Research Centre of Surgery;
Sechenov First Moscow State Medical University (Sechenov University)

Clinical efficacy of carbohydrate preloading in reconstructive esophageal surgery

Authors:

Tarasova I.A., Tshkovrebov A.T., Bitarov T.T., Boeva I.A., Ivanova M.Yu., Shestakov A.L.

More about the authors

Journal: Pirogov Russian Journal of Surgery. 2024;(12‑2): 83‑90

DOI: 10.17116/hirurgia202412283

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Table of contents

CLINICAL EFFICACY OF CARBOHYDRATE PRELOADING IN RECONSTRUCTIVE ESOPHAGEAL SURGERY
CLINICAL EFFICACY OF CARBOHYDRATE PRELOADING IN RECONSTRUCTIVE ESOPHAGEAL SURGERY

To cite this article:

Tarasova IA, Tshkovrebov AT, Bitarov TT, Boeva IA, Ivanova MYu, Shestakov AL. Clinical efficacy of carbohydrate preloading in reconstructive esophageal surgery. Pirogov Russian Journal of Surgery. 2024;(12‑2):83‑90. (In Russ.)
https://doi.org/10.17116/hirurgia202412283

Подписка 2026 Хирургия. Журнал им. Н.И. Пирогова (Pirogov Russian Journal of Surgery)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Recommended articles:
The role of malnutrition in the deve­lopment of complications after esophagoplasty. Piro­gov Russian Journal of Surgery. 2025;(10-2):57-63
Abstract:

OBJECTIVE

To evaluate clinical efficacy of preoperative carbohydrate loading as a component of ERAS in esophageal reconstructive surgery.

MATERIAL AND METHODS

Post hoc analysis included 162 patients who underwent esophageal reconstructive interventions with ERAS principles between 2014 and 2024. The main group (n=61, CHO+) included patients who were metabolically loaded with carbohydrates in preoperative period with 12.5% maltodextrin solution 800 mL the day before and 400 mL 2 hours before surgery per os or enterally. The control group consisted of patients without carbohydrate load (n=101, CHO–). Primary endpoint was length of hospital-stay, secondary control points — postoperative glycemia and complication rate.

RESULTS

Both groups were comparable in sex, age, character of the main and comorbid diseases, body mass index. Patients with CHO had significant lower incidence of respiratory complications (p=0.034). Both groups did not differ in the incidence of anastomosis failure, morbidity and mortality.

CONCLUSION

Preoperative carbohydrate loading in esophageal reconstructive surgery positively affects metabolic status and reduces the incidence of respiratory complications without effect on length of hospital-stay.

Keywords:

carbohydrate preload
metabolic status
esophageal repair
enhanced recovery after surgery

Authors:

Tarasova I.A.

Petrovsky National Research Centre of Surgery;
Sechenov First Moscow State Medical University (Sechenov University)

Tshkovrebov A.T.

Petrovsky National Research Centre of Surgery

Bitarov T.T.

Petrovsky National Research Centre of Surgery

Boeva I.A.

Petrovsky National Research Centre of Surgery

Ivanova M.Yu.

Sechenov First Moscow State Medical University (Sechenov University)

Shestakov A.L.

Petrovsky National Research Centre of Surgery;
Sechenov First Moscow State Medical University (Sechenov University)

Received:

14.08.2024

Accepted:

03.09.2024

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