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Kondakov A.K.

Petrovsky National Research Center of Surgery;
N.I. Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation

Mosin D.Yu.

Petrovsky National Research Center of Surgery;
N.I. Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation

Bashirova M.V.

Petrovsky National Research Center of Surgery

Moshkova E.N.

Petrovsky National Research Center of Surgery

Znamenskiy I.A.

Petrovsky National Research Center of Surgery;
N.I. Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation

Sozykin A.V.

Petrovsky National Research Center of Surgery

Butenko A.V.

Petrovsky National Research Center of Surgery

Cost-effectiveness of using rubidium-82 chloride perfusion PET for planning myocardial revascularization procedures

Authors:

Kondakov A.K., Mosin D.Yu., Bashirova M.V., Moshkova E.N., Znamenskiy I.A., Sozykin A.V., Butenko A.V.

More about the authors

Journal: Pirogov Russian Journal of Surgery. 2024;(12‑2): 58‑65

DOI: 10.17116/hirurgia202412258

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Table of contents

COST-EFFECTIVENESS OF USING RUBIDIUM-82 CHLORIDE PERFUSION PET FOR PLANNING MYOCARDIAL REVASCULARIZATION PROCEDURES
COST-EFFECTIVENESS OF USING RUBIDIUM-82 CHLORIDE PERFUSION PET FOR PLANNING MYOCARDIAL REVASCULARIZATION PROCEDURES

To cite this article:

Kondakov AK, Mosin DYu, Bashirova MV, Moshkova EN, Znamenskiy IA, Sozykin AV, Butenko AV. Cost-effectiveness of using rubidium-82 chloride perfusion PET for planning myocardial revascularization procedures. Pirogov Russian Journal of Surgery. 2024;(12‑2):58‑65. (In Russ.)
https://doi.org/10.17116/hirurgia202412258

Подписка 2026 Хирургия. Журнал им. Н.И. Пирогова (Pirogov Russian Journal of Surgery)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

Objective: The aim of this study is to evaluate the cost-effectiveness, diagnostic accuracy, clinical outcomes, and radiation exposure associated with rubidium-82 chloride perfusion PET. Methods: A comprehensive literature search up to October 2024 was conducted to identify key studies assessing the use of rubidium-82 chloride perfusion PET/CT in ischemic heart disease (IHD). These studies included economic analyses, evaluations of diagnostic accuracy, and comparisons with other imaging modalities such as single-photon emission computed tomography (SPECT), stress echocardiography, and invasive coronary angiography. Results: The reviewed studies demonstrate that rubidium-82 chloride perfusion PET/CT has high sensitivity and specificity in detecting IHD (90% and 91%, respectively) accompanied by significant coronary artery stenosis. Economic analyses show that this method is cost-effective due to a reduction in the use of downstream invasive procedures, leading to overall cost savings. Additionally, the economic impact on healthcare is enhanced by a lower level of radiation exposure compared to traditional perfusion SPECT imaging, reducing associated future radiation risks. The cost-effectiveness and minimum patient throughput required for implementing this modality In Russia were evaluated. Conclusion: The presented data confirm the cost-effectiveness of rubidium-82 chloride perfusion PET/CT by reducing costs for subsequent diagnostic and therapeutic interventions while maintaining a sufficient patient flow.

Keywords:

Rubidium-82 chloride
perfusion PET/CT
cost-effectiveness
Ischemic Heart Disease
diagnostic accuracy
radiation exposure
myocardial imaging

Authors:

Kondakov A.K.

Petrovsky National Research Center of Surgery;
N.I. Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation

Mosin D.Yu.

Petrovsky National Research Center of Surgery;
N.I. Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation

Bashirova M.V.

Petrovsky National Research Center of Surgery

Moshkova E.N.

Petrovsky National Research Center of Surgery

Znamenskiy I.A.

Petrovsky National Research Center of Surgery;
N.I. Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation

Sozykin A.V.

Petrovsky National Research Center of Surgery

Butenko A.V.

Petrovsky National Research Center of Surgery

Received:

18.09.2024

Accepted:

11.10.2024

Close metadata

References:

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