Regional and peripheral blockades for prevention of chronic post-thoracotomy pain syndrome in oncosurgical practice

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Khoronenko V.E.

FGAOU VO «The First Moscow State Medical University named after I.M. Sechenov» Ministry of Health of Russia, Moscow, Russia

Malanova A.S.

Herzen Moscow Research Oncology Institute, the branch of National Medical Research Radiological Center, Ministry of Health of Russia, Moscow, Rusia

Baskakov D.S.

P.A. Hertsen Moscow Oncology Research Center, a branch of Scientific Research Center of Radiology under the Ministry of Health of Russia, 125284, Moscow, Russia

Ryabov A.B.

Hertsen Moscow Oncology Research Center, Moscow, Russia

Pikin O.V.

FGBU "MNIOI im. P.A. Gertsena" Minzdrava Rossii

Regional and peripheral blockades for prevention of chronic post-thoracotomy pain syndrome in oncosurgical practice

Authors:

Khoronenko V.E., Malanova A.S., Baskakov D.S., Ryabov A.B., Pikin O.V.

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Journal: Pirogov Russian Journal of Surgery. 2017;(8): 58‑63

DOI: 10.17116/hirurgia2017858-63

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To cite this article:

Khoronenko VE, Malanova AS, Baskakov DS, Ryabov AB, Pikin OV. Regional and peripheral blockades for prevention of chronic post-thoracotomy pain syndrome in oncosurgical practice. Pirogov Russian Journal of Surgery. 2017;(8):58‑63. (In Russ.)
https://doi.org/10.17116/hirurgia2017858-63

Подписка 2026 Хирургия. Журнал им. Н.И. Пирогова (Pirogov Russian Journal of Surgery)

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Abstract:

Aim. To compare an effectiveness of thoracic epidural anesthesia/analgesia, paravertebral and intercostal blockades in prevention of chronic post-thoracotomy pain syndrome (CPTPS) in oncosurgery. Material and methods. There were 300 patients who underwent open surgery including lobectomy or pneumonectomy. Patients were randomized into 3 groups depending on type of anesthesia: TEA (n=100) — combined general and epidural anesthesia; PVB (n=50) — combined general and paravertebral anesthesia; ICB (n=50) — general anesthesia was supplemented by intercostal blockade after removal of the drug. Results. CPTPS incidence was 34 and 40% in 6 months postoperatively after PVB and ICB, respectively (p>0.05). In TEA group this value was significantly lower compared with ICB group (23%, p<0.05). Conclusion. TEA contributes to significant reduction of CPTPS incidence, while paravertebral blockade does not affect the frequency of this complication.

Keywords:

regional and peripheral blockades

chronic post-thoracotomy pain syndrome

Authors:

Khoronenko V.E.

FGAOU VO «The First Moscow State Medical University named after I.M. Sechenov» Ministry of Health of Russia, Moscow, Russia

Malanova A.S.

Herzen Moscow Research Oncology Institute, the branch of National Medical Research Radiological Center, Ministry of Health of Russia, Moscow, Rusia

Baskakov D.S.

P.A. Hertsen Moscow Oncology Research Center, a branch of Scientific Research Center of Radiology under the Ministry of Health of Russia, 125284, Moscow, Russia

Ryabov A.B.

Hertsen Moscow Oncology Research Center, Moscow, Russia

Pikin O.V.

FGBU "MNIOI im. P.A. Gertsena" Minzdrava Rossii

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References:

Gilron I, Kehlet H. Prevention of chronic pain after surgery: new insights for future research and patient care. Canadian Journal of Anesthesia. 2013;61(2):101-111. https://doi.org/10.1007/s12630-013-0067-8
Macrae WA. Chronic post-surgical pain: 10 years on Article in BJA British. Anaesthesia. 2008;101(1):77-86. https://doi.org/10.1093/bja/aen099
Gorshkov VYu. Khirurgicheskoe lechenie rasprostranennogo raka legkogo. Nizhnii Novgorod: Nizhegorodskaya gosudarstvennaya meditsinskaya iakademiya; 2000. (In Russ.).
Leo, Venissac N, Pop D, Anziani M, et al. Anticipating pulmonary complications after thoracotomy: the FLAM Score. Cardiothoracic Surgery. 2006;34(1):164-172. https://doi.org/10.1186/1749-8090-1-34
Kehlet H. Labat lecture 2005: surgical stress and postoperative outcome — from here to where? Regional Anesthesia and Pain Medicine. 2006;31:47-52. https://doi.org/10.1097/00115550-200601000-00010
Steegers MA, Snik DM, Verhagen AF, et al. Pregabalin reduces post-surgical pain after thoracotomy: a prospective, randomized, controlled trial. Surgery Today. 2014;45(11):1411-1416. https://doi.org/10.1007/s00595-014-1088-9
Searle RD, Simpson MP, Simpson KH, Milton R, Bennett MI. Can chronic neuropathic pain following thoracic surgery be predicted during the postoperative period? Interactive CardioVascular and Thoracic Surgery. 2009;9(6):999-1002. https://doi.org/10.1510/icvts.2009.216887
Twijnstra ARH, Dahan A, Kuile MM, Jansen FW, et al. Nociceptive and stress hormonal state during abdominal, laparoscopic, and vaginal hysterectomy as predictors of postoperative pain perception. Gynecological Surgery. 2007;10 (1):45-50. https://doi.org/10.1007/s10397-012-0769-x
Merskey H. Taxonomy and Classification of Chronic Pain Syndromes. Raj’s Practical Management of Pain. 2008;1:113-118. https://doi.org/10.1016/b978-032304184-3.50005-4
Amr YM, Yousef AA, Alzeftawy AE, et al. Effect of preincisional epidural fentanyl and bupivacaine on postthoracotomy pain and pulmonary function. The Annalsof Thoracic Surgery. 2010;89(2):381-385. https://doi.org/10.1016/j.athoracsur.2009.10.060
Tommaso CМ. Epidural anesthesia in awake thoracic surgery. Cardio-Thoracic Surgery. 2007;32(1)13-19. https://doi.org/10.1016/j.ejcts.2007.04.004
Sentürk M, Ozcan PE, Talu GK, et al. The effects of three different analgesia techniques on long-term postthoracotomy pain. Anesthesia & Analgesia. 2002;94(1):11-15. https://doi.org/10.1213/00000539-200201000-00003
Yoshimura N, Iida H, Takenaka M, et al. Effect of Postoperative Administration of Pregabalin for Post-thoracotomy Pain: A Randomized Study. Cardiothoracicand Vascular Anesthesia. 2015;29(6):1567-1572. https://doi.org/10.1053/j.jvca.2015.05.117
Matthews PJ, Govenden V. Comparison of continuous paravertebral and extradural infusions of bupivacaine for pain relief after thoracotomy. BJA: British Journal of Anaesthesia. 1989;62(2):204-205. https://doi.org/10.1093/bja/62.2.204
Grider JS, Mullet TW, Saha SP, et al. A randomized, double-blind trial comparing continuous thoracic epidural bupivacaine with and without opioid in contrast to a continuous paravertebral infusion of bupivacaine for postthoracotomy pain. Cardiothoracicand Vascular Anesthesia. 2012;26(1):83-89. https://doi.org/10.1053/j.jvca.2011.09.003
Coveney E, Weltz CR, Greengrass R, et al. Use of paravertebral block anaesthesia in the surgical management of breast cancer: experience in 156 cases. Annals of Surgery. 1998;227(4):496-501. https://doi.org/10.1097/00000658-199804000-00008
Lonnqvist PA, MacKenzie J, Soni AK, Conacher ID. Paravertebral blockade: failure rate and complications. Anaesthesia. 1995;50(9):813-815. https://doi.org/10.1111/j.1365-2044.1995.tb06148.x
Norum НМ, Breivik Н. Thoracic Paravertebral Blockade and Thoracic Epidural Analgesia. Anesthesia & Analgesia. 2011;112(40):990. https://doi.org/10.1213/ane.0b013e318209e130
Wildgaard K, Ravn J, Kehlet H. Chronic post-thoracotomy pain: a critical review of pathogenic mechanisms and strategies for prevention. European Journal of Cardio-Thoracic Surgery. 2009;36(1):170-180. https://doi.org/10.1016/j.ejcts.2009.02.005
Karmaker МК. Thoracic Paravertebral Block. Anesthesiology. 2001;95:771-780. https://doi.org/10.1097/00000542-200109000-00033

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