The effect of cytokine therapy on the results of surgical treatment of patients with acute ulcerative gastroduodenal bleeding

Gadzhiev J.N.; Allahverdiyev V.A.; Sushkov S.V.; Klimova E.M.; Gadzhiev N.J.

doi:https://doi.org/10.17116/hirurgia2016657-61

Gadzhiev J.N.

Azerbaijan Medical University, Baku, Azerbaijan

Allahverdiyev V.A.

Azerbaijan Medical University, Baku, Azerbaijan

Sushkov S.V.

V.T. Zaitsev Institute of General and Emergency Surgery of AMS of Ukraine, Khar’kov, Ukraine

Klimova E.M.

V.T. Zaitsev Institute of General and Emergency Surgery of AMS of Ukraine, Khar’kov, Ukraine

Gadzhiev N.J.

Azerbaijan Medical University, Baku, Azerbaijan

The effect of cytokine therapy on the results of surgical treatment of patients with acute ulcerative gastroduodenal bleeding

Authors:

Gadzhiev J.N., Allahverdiyev V.A., Sushkov S.V., Klimova E.M., Gadzhiev N.J.

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Journal: Pirogov Russian Journal of Surgery. 2016;(6): 57‑61

DOI: 10.17116/hirurgia2016657-61

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To cite this article:

Gadzhiev JN, Allahverdiyev VA, Sushkov SV, Klimova EM, Gadzhiev NJ. The effect of cytokine therapy on the results of surgical treatment of patients with acute ulcerative gastroduodenal bleeding. Pirogov Russian Journal of Surgery. 2016;(6):57‑61. (In Russ.)
https://doi.org/10.17116/hirurgia2016657-61

Подписка 2026 Хирургия. Журнал им. Н.И. Пирогова (Pirogov Russian Journal of Surgery)

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Abstract:

Aim. To improve the results of surgical treatment of patients with acute ulcerative gastroduodenal bleeding using immune correction with β-leukin. Material and methods. Urgent and elective operations were performed in 120 patients with gastroduodenal ulcers. Patients of the main group (n=63) received systemic cytokine therapy with β-leukin in addition to conventional treatment. Pre- and postoperative immune correction was absent in the comparison group. Results and discussion. There was preoperative imbalance of antiphlogistic and proinflammatory cytokines in comparison group. Severity of this process depended on blood loss. Therapy with interleukin decreased severity of cytokine imbalance.

Keywords:

acute ulcerative gastroduodenal bleeding

postoperative management

cytokines efficocy

Authors:

Gadzhiev J.N.

Azerbaijan Medical University, Baku, Azerbaijan

Allahverdiyev V.A.

Azerbaijan Medical University, Baku, Azerbaijan

Sushkov S.V.

V.T. Zaitsev Institute of General and Emergency Surgery of AMS of Ukraine, Khar’kov, Ukraine

Klimova E.M.

V.T. Zaitsev Institute of General and Emergency Surgery of AMS of Ukraine, Khar’kov, Ukraine

Gadzhiev N.J.

Azerbaijan Medical University, Baku, Azerbaijan

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References:

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