Comparative effectiveness of different treatment methods of liver failure

Kutepov D.E.

Klinicheskaia bol'nitsa #1

Vershinina M.G.

Tsentral'naia klinicheskaia bol'nitsa s poliklinikoĭ Upravleniia delami Prezidenta RF, Moskva

Pasechnik I.N.

Central State Medical Academy of the Presidential Administration of the Russian Federation

Sal'nikov P.S.

Tsentral'naia klinicheskaia bol'nitsa s poliklinikoĭ Upravleniia delami Prezidenta RF, Moskva

Comparative effectiveness of different treatment methods of liver failure

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Kutepov D.E., Vershinina M.G., Pasechnik I.N., Sal'nikov P.S.

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Journal: Pirogov Russian Journal of Surgery. 2014;(3): 32‑36

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To cite this article:

Kutepov DE, Vershinina MG, Pasechnik IN, Sal'nikov PS. Comparative effectiveness of different treatment methods of liver failure. Pirogov Russian Journal of Surgery. 2014;(3):32‑36. (In Russ.)

Подписка 2025 (Pirogov Russian Journal of Surgery)

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It was analyzed the results of treatment of 217 patients (139 men, 78 women) with chronic liver failure in case of liver cirrhosis of various etiology for study of degree of hepatic encephalopathyregression. All patients were divided into 3 groups. In the first group the drug therapy was used. In the second group additionallyplasma exchange was performed, in the third group - alsomolecular absorbent recirculating system was used (effectiveness of MARS-therapy).The results showed that the use of extracorporeal treatment techniques can effectively reduce the severity of hepatic encephalopathy in patients with liver cirrhosis. MARS-therapy improved the neurological status of patientsmore significantly in this case. It is considered that the inclusion of MARS-therapy in the combined treatment of patients leads to a significant reduction of hepatic encephalopathyseverity (1-2 points), in comparison with other methods of treatment.

Keywords:

liver failure

hepatic encephalopathy

extracorporeal methods of treatment

Authors:

Kutepov D.E.

Klinicheskaia bol'nitsa #1

Vershinina M.G.

Tsentral'naia klinicheskaia bol'nitsa s poliklinikoĭ Upravleniia delami Prezidenta RF, Moskva

Pasechnik I.N.

Central State Medical Academy of the Presidential Administration of the Russian Federation

Sal'nikov P.S.

Tsentral'naia klinicheskaia bol'nitsa s poliklinikoĭ Upravleniia delami Prezidenta RF, Moskva

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