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Vorobyeva A.V.

Almazov National Medical Research Centre

Kudaev Yu.A.

Almazov National Medical Research Center

Lokhovinina N.L.

Almazov National Medical Research Center

Abesadze I.T.

Almazov National Medical Research Center

Alugishvili M.Z.

Almazov National Medical Research Center

Titenkov I.V.

Almazov National Medical Research Center

Kozulin V.Yu.

Almazov National Medical Research Center

Panov A.V.

Almazov National Medical Research Center

Myocardial injury following elective percutaneous coronary interventions: prevalence, risk factors and prognostic significance

Authors:

Vorobyeva A.V., Kudaev Yu.A., Lokhovinina N.L., Abesadze I.T., Alugishvili M.Z., Titenkov I.V., Kozulin V.Yu., Panov A.V.

More about the authors

Journal: Russian Journal of Cardiology and Cardiovascular Surgery. 2025;18(3): 261‑268

DOI: 10.17116/kardio202518031261

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Table of contents

MYOCARDIAL INJURY FOLLOWING ELECTIVE PERCUTANEOUS CORONARY INTERVENTIONS: PREVALENCE, RISK FACTORS AND PROGNOSTIC SIGNIFICANCE
MYOCARDIAL INJURY FOLLOWING ELECTIVE PERCUTANEOUS CORONARY INTERVENTIONS: PREVALENCE, RISK FACTORS AND PROGNOSTIC SIGNIFICANCE

To cite this article:

Vorobyeva AV, Kudaev YuA, Lokhovinina NL, et al. . Myocardial injury following elective percutaneous coronary interventions: prevalence, risk factors and prognostic significance. Russian Journal of Cardiology and Cardiovascular Surgery. 2025;18(3):261‑268. (In Russ.)
https://doi.org/10.17116/kardio202518031261

ЭндоКард
Подписка 2026 Кардиология и сердечно-сосудистая хирургия (Russian Journal of Cardiology and Cardiovascular Surgery)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

OBJECTIVE

To assess the incidence of myocardial injury according to serum cardiac troponin (cTn), the factors of its development and prognostic significance in long-term period in patients with coronary artery disease (CAD) after elective percutaneous coronary intervention (PCI).

MATERIAL AND METHODS

The study included 114 patients with CAD hospitalized for PCI. Serum cTn was analyzed before and 24 hours after coronary revascularization. In postoperative period, cTn-based incidence of myocardial injury was assessed. Major adverse cardiovascular events (MACE) and their relationship with myocardial injury were analyzed throughout 60 months.

RESULTS

In 25 (22%) cases, serum cTn in 24 hours after PCI exceeded the threshold values that indicated myocardial injury after coronary revascularization. In both groups, patients were comparable in basic clinical characteristics and drug therapy. Stenting of the left main coronary artery (16% vs. 3%, p=0.02), bifurcation with two or more stents (24% vs. 9%, p=0.04), circumflex arteries (48% vs. 24%, p=0.02), recanalization of chronic occlusion (20% vs. 6%, p=0.02), implantation of three or more stents (48% vs. 13%, p<0.001) and predilatation of stenosis (88% vs. 61%, p=0.01) were more common in patients with myocardial injury. Significant between-group differences in long-term period were obtained regarding the incidence of MACE (non-fatal myocardial infarction, rhythm disturbances, heart failure and mortality) (52% vs. 25%, p=0.01).

CONCLUSION

Myocardial injury is a common complication of elective PCI and accompanied by high rates of long-term MACE. The risk of myocardial injury is associated with location of coronary artery lesion, complexity of stenosis and characteristics of PCI.

Keywords:

coronary artery disease
myocardial injury
cardiac troponin
percutaneous coronary intervention

Authors:

Vorobyeva A.V.

Almazov National Medical Research Centre

Kudaev Yu.A.

Almazov National Medical Research Center

Lokhovinina N.L.

Almazov National Medical Research Center

Abesadze I.T.

Almazov National Medical Research Center

Alugishvili M.Z.

Almazov National Medical Research Center

Titenkov I.V.

Almazov National Medical Research Center

Kozulin V.Yu.

Almazov National Medical Research Center

Panov A.V.

Almazov National Medical Research Center

Received:

01.02.2024

Accepted:

02.07.2024

Close metadata

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