Prognostic value of modified Syntax Score in high- and medium-risk patients with multiple-vessel coronary artery disease and involvement of the left main coronary artery

Mardanyan G.V.; Vartanyan E.L.; Puretsky M.V.; Polyakov R.S.; Pirkova A.A.; Kudrinskiy A.V.; Kraynikov D.A.; Abugov S.A.

doi:https://doi.org/10.17116/kardio202114051407

Mardanyan G.V.

Petrovsky National Research Center of Surgery

ORCID: 0000-0002-7442-520X

Vartanyan E.L.

Petrovsky Russian Research Center of Surgery

Puretsky M.V.

Petrovsky National Research Center of Surgery;
Russian Medical Academy of Continuous Professional Education

ORCID: 0000-0003-4988-4102

Polyakov R.S.

Petrovsky National Research Center of Surgery;
Russian Medical Academy of Continuous Professional Education

ORCID: 0000-0002-9323-4003

Pirkova A.A.

Petrovsky National Research Center of Surgery

ORCID: 0000-0002-5101-1004

Kudrinskiy A.V.

Petrovsky National Research Centre of Surgery

Kraynikov D.A.

Petrovsky Russian Research Center of Surgery

Abugov S.A.

Petrovsky National Research Center of Surgery;
Russian Medical Academy of Continuous Professional Education

ORCID: 0000-0001-7636-4044

Prognostic value of modified Syntax Score in high- and medium-risk patients with multiple-vessel coronary artery disease and involvement of the left main coronary artery

Authors:

Mardanyan G.V., Vartanyan E.L., Puretsky M.V., Polyakov R.S., Pirkova A.A., Kudrinskiy A.V., Kraynikov D.A., Abugov S.A.

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Journal: Russian Journal of Cardiology and Cardiovascular Surgery. 2021;14(5): 407‑412

DOI: 10.17116/kardio202114051407

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To cite this article:

Mardanyan GV, Vartanyan EL, Puretsky MV, et al. . Prognostic value of modified Syntax Score in high- and medium-risk patients with multiple-vessel coronary artery disease and involvement of the left main coronary artery. Russian Journal of Cardiology and Cardiovascular Surgery. 2021;14(5):407‑412. (In Russ.)
https://doi.org/10.17116/kardio202114051407

Подписка 2026 Кардиология и сердечно-сосудистая хирургия (Russian Journal of Cardiology and Cardiovascular Surgery)

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OBJECTIVE

This study aims to define the prognostic value of a modified Syntax Score in patients with multivessel coronary artery disease and involvement left main coronary artery.

MATERIALS AND METHODS

Our study included 120 patients with multivessel coronary artery disease involving the left main coronary artery with intermediate and high Syntax Score and was made in a retrospective and prospective fashion. The mean follow-up time was 42±22 months. Comparing to the conventional Syntax Score scale the Modified Syntax Score (MSS) is the sum of the scores calculated in arteries greater than 2.0 mm in diameter and with stenosis greater 70%. Analysis and comparison of long-term results of the percutaneous coronary intervention (PCI) in patients with intermediate conventional SS and MSS were performed to assess the prognostic value of MSS.

RESULTS

After a reassessment of coronary angiograms using Modified Syntax Score all patients were distributed in three groups including 38.3% of low MSS, 40% and 21.7% of intermediate and high MSS correspondingly. There is no significant difference in combined endpoint (death, myocardial infarction, stroke and reintervention) between subgroups with intermediate value of conventional SS and MSS comparing results at 42 months of follow up (12.7% vs 22.9%, p=0.21, RR=0.49, 95% CI [0.2—1.32]).

CONCLUSION

Modified Syntax Score possess comparable prognostic value with conventional Syntax Score in patients with multivessel coronary artery disease involving left main coronary artery with intermediate and high Syntax Score according to the results of 3.5 year follow-up time.

Keywords:

Syntax Score

modified Syntax Score

multivessel coronary artery disease involving left main coronary artery

Syntax Score

modified Syntax Score

multivessel coronary artery disease involving left main coronary artery

Authors:

Mardanyan G.V.

Petrovsky National Research Center of Surgery

ORCID: 0000-0002-7442-520X

Vartanyan E.L.

Petrovsky Russian Research Center of Surgery

Puretsky M.V.

Petrovsky National Research Center of Surgery;
Russian Medical Academy of Continuous Professional Education

ORCID: 0000-0003-4988-4102

Polyakov R.S.

Petrovsky National Research Center of Surgery;
Russian Medical Academy of Continuous Professional Education

ORCID: 0000-0002-9323-4003

Pirkova A.A.

Petrovsky National Research Center of Surgery

ORCID: 0000-0002-5101-1004

Kudrinskiy A.V.

Petrovsky National Research Centre of Surgery

Kraynikov D.A.

Petrovsky Russian Research Center of Surgery

Abugov S.A.

Petrovsky National Research Center of Surgery;
Russian Medical Academy of Continuous Professional Education

ORCID: 0000-0001-7636-4044

Received:

12.10.2020

Accepted:

14.05.2021

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References:

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