Aim. To present the results of cerebral blood flow monitoring during off-pump coronary artery bypass grafting (CABG). Material and methods. It was performed 327 off-pump coronary bypass interventions at the Clinic of Aortic and Cardiovascular Surgery. We applied bilateral measurement of peak systolic velocity (Vs) and mean velocity of blood flow (Vm) in M1 segment of middle cerebral artery (MCA) during 23 operations. Results. Significant changes of blood flow velocity in M1 segment of MCA at various stages of off-pump CABG were not observed.