Efficacy evaluation of various treatment options of ventricular arrhythmias

Treshkur T.V.; Tulintseva T.E.; Zhabina E.S.; Ovechkina M.A.; Alekseeva D.Yu.; Zhdanova O.N.

doi:https://doi.org/10.17116/Cardiobulletin20191401146

Treshkur T.V.

Almazov National Medical Research Centre, St.-Petersburg, Russia

Tulintseva T.E.

Almazov National Medical Research Centre, St.-Petersburg, Russia

Zhabina E.S.

Almazov National Medical Research Centre, St.-Petersburg, Russia

Ovechkina M.A.

Almazov National Medical Research Centre, St.-Petersburg, Russia

Alekseeva D.Yu.

Almazov National Medical Research Centre, St.-Petersburg, Russia

Zhdanova O.N.

First Pavlov State Medical University of St.-Petersburg, Russia

Efficacy evaluation of various treatment options of ventricular arrhythmias

Authors:

Treshkur T.V., Tulintseva T.E., Zhabina E.S., Ovechkina M.A., Alekseeva D.Yu., Zhdanova O.N.

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Journal: Russian Cardiology Bulletin. 2019;14(1): 46‑53

DOI: 10.17116/Cardiobulletin20191401146

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To cite this article:

Treshkur TV, Tulintseva TE, Zhabina ES, Ovechkina MA, Alekseeva DYu, Zhdanova ON. Efficacy evaluation of various treatment options of ventricular arrhythmias. Russian Cardiology Bulletin. 2019;14(1):46‑53. (In Russ.)
https://doi.org/10.17116/Cardiobulletin20191401146

Подписка 2026 Кардиологический вестник (Russian Cardiology Bulletin)

Использование инфографики авторами научных работ

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Abstract:

The aim. To compare the results of different methods of antiarrhythmic therapy of non-coronary ventricular arrhythmias. Material and methods. The study included 312 patients with premature ventricular contractions more than 500 per day, ejection fraction over 55%, age over 18 years old. The follow-up period was 12—36 months. There were used 24-hour and long-term ECG monitoring, exercise treadmill test, psychological testing, mental stress testing for therapeutic decision and efficacy control. Results. According to the examination data, the influence of autonomic nervous system and therapeutic decision all patients were divided into four groups. Efficacy of drug (I, II, III groups) and surgical (IV group) treatment was the same and more than 70% during whole period of the study. The best results were shown by patients suffering from ventricular arrhythmias for less than 5 years. Conclusions. High and comparable efficacy of drug therapy and catheter ablation is observed at a differentiated approach.

Keywords:

ventricular arrhythmias

Holter monitoring

exercise test

psychological testing

therapeutic decision

Authors:

Treshkur T.V.

Almazov National Medical Research Centre, St.-Petersburg, Russia

Tulintseva T.E.

Almazov National Medical Research Centre, St.-Petersburg, Russia

Zhabina E.S.

Almazov National Medical Research Centre, St.-Petersburg, Russia

Ovechkina M.A.

Almazov National Medical Research Centre, St.-Petersburg, Russia

Alekseeva D.Yu.

Almazov National Medical Research Centre, St.-Petersburg, Russia

Zhdanova O.N.

First Pavlov State Medical University of St.-Petersburg, Russia

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References:

Al-Khatib S, Stevenson W, Ackerman M, Bryant W, Callans D, Curtis A, Deal B, Dickfeld T, Field M, Fonarow G, Gillis A, Hlatky M, Granger C, Hammill S, Joglar J, Neal Kay G, Matlock D, Myerburg R, Page R. 2017 AHA/ACC/HRS Guideline for Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death. Circulation. 2017;137(10):1-551. https://doi.org/10.1161/cir.0000000000000549
Revishvili ASh, Neminushchiy NM, Batalov RE. Vserossiyskiye klinicheskiye rekomendatsii po kontrolyu nad riskom vnezapnoy ostanovki serdtsa i vnezapnoy serdechnoy smerti, profilaktike i okazaniyu pervoy pomoshchi. M.: GEOTAR-Media; 2018. (In Russ.)
Mallidi J, Nadkarni G, Berger R, Calkins H, Nazarian S. Meta-analysis of catheter ablation as an adjunct to medical therapy for treatment of ventricular tachycardia in patients with structural heart disease. Heart Rhythm. 2011;8(4):503-510. https://doi.org/10.1016/j.hrthm.2010.12.015
Bhaskaran A, Chik W, Thomas S, Kovoor P, Thiagalingam A. A review of the safety aspects of radio frequency ablation. IJC Heart & Vasculature. 2015;8(1):147-153. https://doi.org/10.1016/j.ijcha.2015.04.011
Kushakovskiy MS. Aritmii serdtsa. SPb.: Hippocrates; 1992. (In Russ.)
Tatarinova AA, Treshkur TV, Ryngach EA. Algorithm the management of patients with stable coronary artery disease and ventricular arrhythmias. Translational medicine. 2017;4(2):17-28. (In Russ.) https://doi.org/10.18705/2311-4495-2017-4-2-17-28
Holmes D, Kim L, Brooks M, Kip K, Schaff H, Detre K, Frye R. The effect of coronary artery bypass grafting on specific causes of long-term mortality in the Bypass Angioplasty Revascularization Investigation. The Journal of Thoracic and Cardiovascular Surgery. 2007;134(1):38-46. https://doi.org/10.1016/j.jtcvs.2007.01.076
Tsurinova EA. Acute and chronic psychoemotional stress in genesis of ventricular arrhythmias. Translational medicine. 2014;2:18-25. (In Russ.)
Alekseeva DYu, Tsurinova EA, Poltorak SV, Solntsev VN, Treshkur TV. The psychosomatic approach to the management of patients with ventricular arrhythmias. Cardiology and cardiovascular surgery. 2015;8(6):107-113. (In Russ.)
Massimo F, Arno W, Hoes S, Agewall C, Albus C, Brotoos A. 2016 European Guidelines on cardiovascular disease prevention in clinical practice: The Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of 10 societies and by invited experts). Developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation. European Heart Journal Europace. 2014;16(9):1257-1283. https://doi.org/10.1093/europace/euu194
Pedersen C, Kay G, Kalman J, Borggrefe M, Della-Bella P, Dickfeld T, Dorian P, Huikuri H, Kim Y, Knight B, Marchlinski F, Ross D, Sacher F, Sapp J, Shivkumar K, Soejima K, Tada H, Alexander M, Triedman J, Yamada T, Kirchhof P, Lip G, Kuck K, Mont L, Haines D, Indik J, Dimarco J, Exner D, Iesaka Y, Savelieva I. EHRA/HRS/APHRS expert consensus on ventricular arrhythmias. Heart Rhythm. 2014;11(10):168-196. https://doi.org/10.1016/j.joa.2014.08.001
Treshkur T, Panova E, Chmelevsky M, Tsurinova E, Ilina D. Determination of genesis and localization of ventricular ectopic focus in a patient with coronary artery disease. Experimental & clinical cardiology. 2014;20(8):2388-2394.
Priori S, Blomström-Lundqvist C, Mazzanti A, Blom N, Borggrefe M, Camm J, Elliott P, Fitzsimons D, Hatala R, Hindricks G, Kirchhof P, Kjeldsen K, Kuck KH, Hernandez-Madrid A, Nikolaou N, Norekvål TM, Spaulding C, Van Veldhuisen DJ. 2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death. European Heart Journal. 2015;36(41):2793-2867. https://doi.org/10.1016/j.rec.2016.01.001
Zhong L, Lee Y-H, Huang X-M, Asirvatham SJ, Shen W-K, Friedman PA, Hodge DO, Slusser JP, Song Zh-Y, Packer DL, Cha Y-M. Relative efficacy of catheter ablation vs antiarrhythmic drugs intreating premature ventricular contractions: A single-center retrospective study. Kardiologiia. 2014;2:26-36. (In Russ.)
Treshkur TV, Ovechkina MA, Los MM. Comparative effectiveness of intervention and medical treatment of patients with noncoronary ventricular parasystolies. Cardiology and cardiovascular surgery. 2017;4:32-38. (In Russ.) https://doi.org/10.17116/kardio201710432-38
Tsurinova EA, Popov SV, Berngardt EP, Ananyeva NI, Tikhonenko VM, Treshkur TV. Selection of an effective antiarrhythmic therapy using a novel technique of multi-day telemonitoring of electrocardiogram. Journal of arrhythmology. 2014;75:29-34. (In Russ.)
Shlyakhto EV, Treshkur TV, Tulentseva TE, Zhdanova ON, Tikhonenko VM, Tsurinova EA, Ilyina DYu, Los MM. Algorithm of management of patients with ventricular arrhythmias. Therapeutic archive. 2015;5:106-112. (In Russ.) https://doi.org/10.17116/terarkh2015875106-112
Golitsyn SP. Elimination of ventricular arrhythmias and reducing the risk of death: is the way in one direction? Heart. 2006;1:4-11. (In Russ.)
Shlyakhto EV, Treshkur TV, Kapanadze ST. When beta-blockers are the drugs of choice in treatment of ventricular arrhythmias? Hypertension. 2006;2:12:149-155. (In Russ.)
Barkanova OV. Metodiki diagnostiki emotsional’noy sfery. Psikhologicheskiy praktikum K.: Litera-print; 2009. (In Russ.)
Bizyuk AP, Wasserman LI, Iovlev BV. Primeneniye integrativnogo testa trevozhnosti. Metodicheskiye rekomendatsii. SPb.: Izdatel’stvo Psikhonevrologicheskogo instituta im. V.M. Bekhtereva; 2005. (In Russ.)
Steptoe A. Stress and cardiovascular disease. Nature Reviews Cardiology. 2012;9(3):360-370. https://doi.org/10.1038/nrcardio.2012.45
Kardiologiya. Natsional’noye rukovodstvo. 2-e izd. Pod red. Shlyakhto E.V. M.: GEOTAR-Media; 2015. (InRuss.)
Makarov LM, Komolyatova VN, Kupriyanova OO, Pervova EV, Ryabykina GV, Sobolev AV, Tikhonenko VM, Turov AN, Shubik YuV. Natsional’nyye rossiyskiye rekomendatsii po primeneniyu metodiki kholterovskogo monitorirovaniya v klinicheskoy praktike. Russian journal of cardiology. 2014;2(106):6-71. (InRuss.)
Noskova MV, Revishvili ASh. Comparative analysis of the effectiveness of antiarrhythmic drugs in various clinical and electrophysiological variants of non-coronary ventricular arrhythmias. Vestnik aritmologii. 2004;35:22-25. (InRuss.)
De Ferrari G, Schwartz P. Autonomic nervous system and arrhythmias. Annals of the New York Academy of Sciences. 1990;601(1):247-262. https://doi.org/10.1111/j.1749-6632.1990.tb37305.x
Shlyakhto EV, Treshkur TV, Ovechkina MA, Parmon EV. What is vagal ventricular arrhythmias and how to treat them? Cardiology of the CIS. 2006;4:1-8. (In Russ.)
Mkrtchan VP. Management of vegetative disorders in women: Adaptol therapeutic potentials. Doktor ru. 2008;6:1-9. (In Russ.)
Treshkur TV, Tsurinova EA, Tulintseva TE, Parmon EV, Ilyina DYu. In search of optimal treatment for nonischemic ventricular arrhythmia in patients with anxiety disorders. Terapevticheskiy arkhiv. 2012;12:35-39. (In Russ.)