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Zairova A.R.

Federal State budget organization National Medical Research Center of Cardiology of the Ministry of healthcare of the Russian Federation, The Institute of Clinical Cardiology, Moscow, Russia

Rogoza A.N.

Federal State budget organization National Medical Research Center of Cardiology of the Ministry of healthcare of the Russian Federation, The Institute of Clinical Cardiology, Moscow, Russia

Dobrovol'skiĭ A.B.

Rossiĭskiĭ kardiologicheskiĭ nauchno-proizvodstvennyĭ kompleks Minzdravsotsrazvitiia RF, Moskva

Oschepkova E.V.

Federal State budget organization National Medical Research Center of Cardiology of the Ministry of healthcare of the Russian Federation, The Institute of Clinical Cardiology, Moscow, Russia

Titaeva E.V.

Rossiĭskiĭ kardiologicheskiĭ nauchno-proizvodstvennyĭ kompleks Minzdravsotsrazvitiia RF, Moskva

Starostin I.V.

Federal State budget organization National Medical Research Center of Cardiology of the Ministry of healthcare of the Russian Federation, The Institute of Clinical Cardiology, Moscow, Russia

Panchenko E.P.

Rossiĭskiĭ kardiologicheskiĭ nauchno-proizvodstvennyĭ kompleks Minzdravsotsrazvitiia RF, Moskva

Trubacheva I.A.

Federal State budget science organization Tomsk National Research Medical Center of the Russian Academy of Sciences Cardiology Research Institute, Tomsk, Russia

Serebryakova V.N.

Federal State budget science organization Tomsk National Research Medical Center of the Russian Academy of Sciences Cardiology Research Institute, Tomsk, Russia

Kaveshnikov V.S.

Federal State budget science organization Tomsk National Research Medical Center of the Russian Academy of Sciences Cardiology Research Institute, Tomsk, Russia

Chazova I.E.

Federal State budget organization National Medical Research Center of Cardiology of the Ministry of healthcare of the Russian Federation, The Institute of Clinical Cardiology, Moscow, Russia

Karpov R.S.

Federal State budget science organization Tomsk National Research Medical Center of the Russian Academy of Sciences Cardiology Research Institute, Tomsk, Russia

Arterial stiffness and vascular aging in relation to coalugogical CVD risk factors, parameters of lipid and carbohydrate metabolism in adult population of Tomsk in the framework of the project ESSE-RF

Authors:

Zairova A.R., Rogoza A.N., Dobrovol'skiĭ A.B., Oschepkova E.V., Titaeva E.V., Starostin I.V., Panchenko E.P., Trubacheva I.A., Serebryakova V.N., Kaveshnikov V.S., Chazova I.E., Karpov R.S.

More about the authors

Journal: Russian Cardiology Bulletin. 2018;13(1): 5‑15

DOI: 10.17116/Cardiobulletin20181315-15

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Table of contents

ARTERIAL STIFFNESS AND VASCULAR AGING IN RELATION TO COALUGOGICAL CVD RISK FACTORS, PARAMETERS OF LIPID AND CARBOHYDRATE METABOLISM IN ADULT POPULATION OF TOMSK IN THE FRAMEWORK OF THE PROJECT ESSE-RF
ARTERIAL STIFFNESS AND VASCULAR AGING IN RELATION TO COALUGOGICAL CVD RISK FACTORS, PARAMETERS OF LIPID AND CARBOHYDRATE METABOLISM IN ADULT POPULATION OF TOMSK IN THE FRAMEWORK OF THE PROJECT ESSE-RF

To cite this article:

Zairova AR, Rogoza AN, Dobrovol'skiĭ AB, et al. . Arterial stiffness and vascular aging in relation to coalugogical CVD risk factors, parameters of lipid and carbohydrate metabolism in adult population of Tomsk in the framework of the project ESSE-RF. Russian Cardiology Bulletin. 2018;13(1):5‑15. (In Russ.)
https://doi.org/10.17116/Cardiobulletin20181315-15

Подписка 2025-2 (Russian Cardiology Bulletin)
 
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The article describes the results of a study the arterial stiffness and “vascular aging” in relation to CVD risk factors, with a focus on coagulogy indicators (fibrinogen and D-dimer), lipid and carbohydrate metabolism disorders in adult population of Tomsk (841 persons aged 25 to 64 years) in the framework of the project ESSE-RF. Arterial stiffness and “vascular aging” were determined by volumetric sphygmography on the VaSera VS-1500 (Fukuda Denshi, Japan) with CAVI (cardio-ankle vascular index) and PWV aa (pulse wave velocity aorto-ankle) parameters. The role of well known risk factors for increasing arterial stiffness and “vascular aging” such as age, arterial hypertension, diabetes, male gender, hyperglycemia and hypertriglyceridemia was confirmed. Female gender and overweight showed themselves as protective factors of vascular aging. Independent of other risk factors the association of fibrinogen with arterial stiffness in men, as well as an increase in the fibrinogen and D-dimer levels in men and women with “early vascular aging” were revealed.

Keywords:

epidemiological study ESSE-RF
arterial stiffness
vascular aging
fibrinogen
D-dimer
CVD risk factors

Authors:

Zairova A.R.

Federal State budget organization National Medical Research Center of Cardiology of the Ministry of healthcare of the Russian Federation, The Institute of Clinical Cardiology, Moscow, Russia

Rogoza A.N.

Federal State budget organization National Medical Research Center of Cardiology of the Ministry of healthcare of the Russian Federation, The Institute of Clinical Cardiology, Moscow, Russia

Dobrovol'skiĭ A.B.

Rossiĭskiĭ kardiologicheskiĭ nauchno-proizvodstvennyĭ kompleks Minzdravsotsrazvitiia RF, Moskva

Oschepkova E.V.

Federal State budget organization National Medical Research Center of Cardiology of the Ministry of healthcare of the Russian Federation, The Institute of Clinical Cardiology, Moscow, Russia

Titaeva E.V.

Rossiĭskiĭ kardiologicheskiĭ nauchno-proizvodstvennyĭ kompleks Minzdravsotsrazvitiia RF, Moskva

Starostin I.V.

Federal State budget organization National Medical Research Center of Cardiology of the Ministry of healthcare of the Russian Federation, The Institute of Clinical Cardiology, Moscow, Russia

Panchenko E.P.

Rossiĭskiĭ kardiologicheskiĭ nauchno-proizvodstvennyĭ kompleks Minzdravsotsrazvitiia RF, Moskva

Trubacheva I.A.

Federal State budget science organization Tomsk National Research Medical Center of the Russian Academy of Sciences Cardiology Research Institute, Tomsk, Russia

Serebryakova V.N.

Federal State budget science organization Tomsk National Research Medical Center of the Russian Academy of Sciences Cardiology Research Institute, Tomsk, Russia

Kaveshnikov V.S.

Federal State budget science organization Tomsk National Research Medical Center of the Russian Academy of Sciences Cardiology Research Institute, Tomsk, Russia

Chazova I.E.

Federal State budget organization National Medical Research Center of Cardiology of the Ministry of healthcare of the Russian Federation, The Institute of Clinical Cardiology, Moscow, Russia

Karpov R.S.

Federal State budget science organization Tomsk National Research Medical Center of the Russian Academy of Sciences Cardiology Research Institute, Tomsk, Russia

List of references:

  1. Vasyuk YA, Ivanova SV, Shkolnik EL et al. Consensus of Russian experts on the evaluation of arterial stiffness in clinical practice. Kardiovaskulyarnaya terapiya i profilaktika. 2016;15(2):4-19. (In Russ.)
  2. Laurent S, Cockcroft J, van Bortel L et al. Expert consensus document on arterial stiffness: methodological issues and clinical applications. European Heart Journal. 2006;27:2588-605. https://doi.org/10.1093/eurheartj/ehl254
  3. Safar ME, O’Rourke MF. Handbook of Hypertension, Volume 23: Arterial Stiffness in Hypertension. Elsevier; 2006. P. 598.
  4. European Guidelines on cardiovascular disease prevention in clinical practice. European Heart Journal. 2016;7(29);2-78.
  5. ESH/ESC Guidelines for the management of arterial hypertension. European Heart Journal. 2013;34;2159-219.
  6. Chazova IE, Oshepkova EV, Zhernakova YuV. Diagnostics and treatment of arterial hypertension. Clinical guidelines. Kardiologicheskii vestnik. 2015;1:3-30. (In Russ.)
  7. Vlachopoulos C, Aznaouridis K, Stefanadis C. Prediction of Cardiovascular Events and All-Cause Mortality With Arterial Stiffness. A Systematic Review and Meta-Analysis. J Am Coll Cardiol. 2010;55(13):1318-1327.
  8. Nilsson PM, Lurbe E, Laurent S. The early life origins of vascular ageing and cardiovascular risk: the EVA syndrome [review]. Journal of Hypertension. 2008;26:1049-1057. https://doi.org/10.1097/HJH.0b013e3282f82c3e
  9. Nilsson PM, Boutouyrie P, Laurent S. Vascular Aging: A Tale of EVA and ADAM in Cardiovascular Risk Assessment and Prevention. Hypertension. 2009;54:3-10. https://doi.org/10.1161/hypertensionaha.109.129114
  10. Nilsson PM. Preventing early vascular aging (EVA). Medicographia. 2012; 34:11-16.
  11. Boutouyrie P, Vermeersch SJ. Determinants of pulse wave velocity in healthy people and in the presence of cardiovascular risk factors: ‘establishing normal and reference values’: Clinical research. European Heart Journal. 2010;31:2338-2350. https://doi.org/10.1093/eurheartj/ehq165
  12. Van Bortel LM, Laurent S, Boutouyrie P et al. Expert consensus document on the measurement of aortic stiffness in daily practice using carotid-femoral pulse wave velocity. Journal of Hypertension. 2012;30:445-448. https://doi.org/10.1097/hjh.0b013e32834fa8b0
  13. Shirai K, Hiruta N, Song M, Kurosu T et al. Cardio-Ankle Vascular Index (CAVI) as a Novel Indicator of Arterial Stiffness: Theory, Evidence and Perspectives. J Atheroscler Thromb. 2011;18(11):924-938. https://doi.org/10.5551/jat.7716
  14. Namekata T, Suzuki K, Ishizuka N, Shirai K. Establishing baseline criteria of cardio-ankle vascular index as a new indicator of arteriosclerosis: a cross-sectional study. BMC Cardiovasc Disord. 2011;10:11-51. https://doi.org/10.1186/1471-2261-11-51
  15. Miljagin VA, Miljagina IV, Abramenkova NJu. Neinvazivnye metody issledovanija magistral’nyh sosudov. Smolensk. 2008.(In Russ.)
  16. Laurent S, Boutouyrie P, Lacolley P. Structural and genetic bases of arterial stiffness. Hypertension. 2005;45:1050-1055. https://doi.org/10.1161/01.hyp.0000164580.39991.3d
  17. Borissoff JI, Heeneman S, Kilinç E et al. Early Atherosclerosis Exhibits an Enhanced Procoagulant State. Circulation. 2010;122:821-830. https://doi.org/10.1161/circulationaha.109.907121
  18. Willeit P, Thompson A, Aspelund T, Rumley A, Eiriksdottir G et al. Hemostatic Factors and Risk of Coronary Heart Disease in General Populations: New Prospective Study and Updated Meta-Analyses. PLoS ONE. 2013; 8(2):e55175. https://doi.org/10.1371/journal.pone.0055175
  19. Crawley JT, Zanardelli S, Chion CK, Lane DA. The central role of thrombin in hemostasis. J Thromb Haemost. 2007;5(Suppl. 1):95-101. https://doi.org/10.1111/j.1538-7836.2007.02500.x
  20. Vlachopoulos C, Pietri P, Aznaouridis K et al. Relationship of fibrinogen with arterial stiffness and wave reflections. Journal of Hypertension. 2007;25:2110-2116. https://doi.org/10.1097/hjh.0b013e3282dc25da
  21. Arnold N, Gori T, Schnabel RB, Schulz A et al. Relation between Arterial Stiffness and Markers of Inflammation and Hemostasis — Data from the Population-based Gutenberg Health Study. www.nature.com/scientificreports/Published online: 24 July 2017. https://doi.org/10.1038/s41598-017-06175-2
  22. Kaptoge S, White IR, Thompson SG, Wood AM et al. Associations of plasma fibrinogen levels with established cardiovascular disease risk factors, inflammatory markers, and other characteristics: individual participant meta-analysis of 154 211 adults in 31 prospective studies: the fibrinogen studies collaboration. Am J Epidemiol. 2007;166:867-879. https://doi.org/10.1093/aje/kwm191
  23. Lieb W, Larson MG, Benjamin EJ, Yin X et al. Multimarker approach to evaluate correlates of vascular stiffness: the Framingham Heart Study. Circulation. 2009;119:37-43. https://doi.org/10.1161/circulationaha.108.816108
  24. Hayashi S. Significance of plasma D-dimer in relation to the severity of atherosclerosis among patients evaluated by non-invasive indices of cardio-ankle vascular index and carotid intima-media thickness. Int J Hematol. 2010;92:76-82. https://doi.org/10.1007/s12185-010-0622-9
  25. Boitsov SA, Chazov EI, Shlyakhto EV. Epidemiology of cardiovascular diseases in different regions of Russia (ESSE-RF). The rationale for and design of the study. Profilakticheskaya meditsina. 2013;6:25-34.(In Russ.)
  26. Chazova IE, Trubacheva IA, Zhernakova YV. The prevalence of arterial hypertension as a risk factor of cardiovascular diseases in one of the cities in Siberian federal district. Sistemnye gipertenzii. 2013;10(4):30-37. (In Russ.)
  27. Chazova IE, Zhernakova YuV, Oshchepkova EV. Prevalence of Cardiovascular Risk Factors in Russian Population of Patients With Arterial Hypertension. Kardiologiya. 2014;10:4-12. (In Russ.) https://doi.org/10.18565/cardio.2014.10.4-12
  28. Dobrovolsky АB, Тitaeva ЕV, Yarovaya ЕB et al. Coagulogic risk factors of heart disease in the adult population of Tomsk. Sistemnye gipertenzii. 2013;10(4):50-54. (In Russ.)
  29. Dobrovolsky АB, Тitaeva ЕV, Yarovaya ЕB et al. D-dimer, fibrinogen and arterial hypertension in the adult population of Tomsk (the ESSE-RF study). Aterotromboz. 2014;2:19-24.(In Russ.) https://doi.org/10.21518/2307-1109-2014-2-19-24
  30. Rogoza AN, Zairova AR, Zhernakova YV, Oshepkova EV et al. Vascular wall in adult population of Tomsk in the framework of the project ESSAY RF. Sistemnye gipertenzii. 2014;11(4):42-48. (In Russ.)
  31. ESC/EAS Guidelines for the Management of Dyslipidaemias. European Heart Journal 2016;37(39):2999-3058. https://doi.org/10.1093/eurheartj/ehw272
  32. Standards of specialized diabetes care. Edited by Dedov II, Shestakova MV, Mayorov AY. 8th Edition. Saharnyi diabet. 2017;20(1S):1-112.(In Russ.) https://doi.org/ 10.14341/DM20171S8
  33. Zakai NA, McClure LA, Judd SE et al. D-dimer and the Risk of Stroke and Coronary Heart Disease. The REasons for Geographic and Racial Differences in Stroke (REGARDS) Study. Thromb Haemost. 2017;117:618-624. https://doi.org/10.1160/th16-07-0519
  34. Regnault V, Lacolley P, Safar M. Fibrinogen, genes, and arterial stiffness. Journal of Hypertension. 2009;27:1350-1351. https://doi.org/10.1097/hjh.0b013e32832c4e18
  35. Sarwar N, Danesh J, Eiriksdottir G, Sigurdsson G et al Triglycerides and the risk of coronary heart disease: 10,158 incident cases among 262,525 participants in 29 Western prospective studies. Circulation. 2007;115:450-458. https://doi.org/10.1161/circulationaha.106.637793
  36. Gómez-Marcos MÁ, Recio-Rodríguez JI, Patino-Alonso MC et al; LOD-DIABETES Group. Cardio-ankle vascular index is associated with cardiovascular target organ damage and vascular structure and function in patients with diabetes or metabolic syndrome, LOD-DIABETES study: a case series report. Cardiovasc Diabetol. 2015;14:7. https://doi.org/10.1186/s12933-014-0167-y
  37. Oskola EV, Shubina AT, Zairova AR et al. Arterial stiffness, renal function and renal blood flow in patients with coronary artery disease, arterial hypertension and type 2 diabetes mellitus. Saharnyi diabet. 2014;3:96-106.(In Russ.) https://doi.org/ 10.14341/DM2014396-106
  38. Sumin AN, Bezdenezhnykh NA, Fedorova NV et al. The values of cardio-ankle vascular index in patients with impaired glucose metabolism according to research «ECVE-RF» in the Kemerovo region. Ateroskleroz i dislipidemii. 2016;3:55-67. (In Russ.)
  39. Pataky Z, Bobbioni-Harsch E, Golay A. Open questions about metabolically normal obesity. Int J Obes (Lond). 2010;34(Suppl.2):S18-S23. https://doi.org/10.1038/ijo.2010.235
  40. Boyarinova MA, Orlov AV, Rotar OP et al. Adipokines Level in Metabolically Healthy Obese Saint-Petersburg Inhabitants (ESSE-RF). Kardiologiya. 2016;8:40-45. (In Russ.) https://doi.org/10.18565/cardio.2016.8.40-45

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