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Kontorshchikov A.S.

Avtsyn Research Institute of Human Morphology of Petrovsky National Research Centre of Surgery;
City Clinical Hospital No. 31 named after Academician G.M. Savelyeva

Mikhaleva L.M.

Avtsyn Research Institute of Human Morphology of Petrovsky National Research Centre of Surgery;
City Clinical Hospital No. 31 named after Academician G.M. Savelyeva;
Russian Medical Academy of Continuous Professional Education

Sharafetdinova M.A.

Center for Medical Prevention

Vasyukova O.A.

Avtsyn Research Institute of Human Morphology of Petrovsky National Research Centre of Surgery;
City Clinical Hospital No. 31 named after Academician G.M. Savelyeva

Kozlov I.S.

City Clinical Hospital No. 31 named after Academician G.M. Savelyeva

Vandysheva R.A.

Avtsyn Research Institute of Human Morphology of Petrovsky National Research Centre of Surgery

Kakturskiĭ L.V.

Avtsyn Research Institute of Human Morphology of Petrovsky National Research Centre of Surgery

Clinical and laboratory parameters and pathomorphological features of the lungs in patients who have had COVID-19 viral pneumonia

Authors:

Kontorshchikov A.S., Mikhaleva L.M., Sharafetdinova M.A., Vasyukova O.A., Kozlov I.S., Vandysheva R.A., Kakturskiĭ L.V.

More about the authors

Journal: Russian Journal of Archive of Pathology. 2024;86(1): 27‑35

DOI: 10.17116/patol20248601127

Read: 2471 times

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Table of contents

CLINICAL AND LABORATORY PARAMETERS AND PATHOMORPHOLOGICAL FEATURES OF THE LUNGS IN PATIENTS WHO HAVE HAD COVID-19 VIRAL PNEUMONIA
CLINICAL AND LABORATORY PARAMETERS AND PATHOMORPHOLOGICAL FEATURES OF THE LUNGS IN PATIENTS WHO HAVE HAD COVID-19 VIRAL PNEUMONIA

To cite this article:

Kontorshchikov AS, Mikhaleva LM, Sharafetdinova MA, Vasyukova OA, Kozlov IS, Vandysheva RA, Kakturskiĭ LV. Clinical and laboratory parameters and pathomorphological features of the lungs in patients who have had COVID-19 viral pneumonia. Russian Journal of Archive of Pathology. 2024;86(1):27‑35. (In Russ.)
https://doi.org/10.17116/patol20248601127

Подписка 2026 Архив патологии (Russian Journal of Archive of Pathology)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

Post-Covid syndrome is characterized by general somatic manifestations, changes in the psycho-emotional sphere, cognitive disorders, disorders of the cardiovascular, respiratory systems and excretory function. However, there is little information in the literature about the mechanisms of thanatogenesis in patients who have had COVID-19. An analysis of clinical and laboratory parameters and pathomorphological changes was carried out in 9 autopsy cases of patients who had previously suffered a new coronavirus infection (COVID-19). The age of the deceased ranged from 80 to 96 years. At the time of hospitalization, the concentration of IgG varied from 32.61 to 1013.5 RLU, IgM — from 0.29 to 16.98 U/ml. The period from clinical diagnosis to death ranged from 12 to 46 days, and the time from clinical recovery (negative polymerase chain reaction) to death ranged from 2 to 30 days. In all cases, unresolved viral pneumonia and diffuse alveolar damage (exudative-proliferative phase) were diagnosed.

Keywords:

novel coronavirus infection (COVID-19)
SARS-CoV-2
Ig G
IgM
early convalescence phase
pathology
immunohistochemistry

Authors:

Kontorshchikov A.S.

Avtsyn Research Institute of Human Morphology of Petrovsky National Research Centre of Surgery;
City Clinical Hospital No. 31 named after Academician G.M. Savelyeva

Mikhaleva L.M.

Avtsyn Research Institute of Human Morphology of Petrovsky National Research Centre of Surgery;
City Clinical Hospital No. 31 named after Academician G.M. Savelyeva;
Russian Medical Academy of Continuous Professional Education

Sharafetdinova M.A.

Center for Medical Prevention

Vasyukova O.A.

Avtsyn Research Institute of Human Morphology of Petrovsky National Research Centre of Surgery;
City Clinical Hospital No. 31 named after Academician G.M. Savelyeva

Kozlov I.S.

City Clinical Hospital No. 31 named after Academician G.M. Savelyeva

Vandysheva R.A.

Avtsyn Research Institute of Human Morphology of Petrovsky National Research Centre of Surgery

Kakturskiĭ L.V.

Avtsyn Research Institute of Human Morphology of Petrovsky National Research Centre of Surgery

Received:

25.04.2023

Accepted:

12.09.2023

Close metadata

References:

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