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Sitovskaya D.A.

Prof. A.L. Polenov Russian Research Institute of Neurosurgery — Branch V.A. Almazov National Medical Research Center of the Ministry of Health of Russia;
City Mariinskaya Hospital

Verbitsky O.P.

City Mariinskaya Hospital

Petrova Yu.A.

City Mariinskaya Hospital

Sokolova T.V.

Prof. A.L. Polenov Russian Research Institute of Neurosurgery — Branch V.A. Almazov National Medical Research Center of the Ministry of Health of Russia

Zabrodskaya Yu.M.

Prof. A.L. Polenov Russian Research Institute of Neurosurgery — Branch V.A. Almazov National Medical Research Center of the Ministry of Health of Russia

Primary diffuse meningeal melanomatosis: a literature review and a case report

Authors:

Sitovskaya D.A., Verbitsky O.P., Petrova Yu.A., Sokolova T.V., Zabrodskaya Yu.M.

More about the authors

Journal: Russian Journal of Archive of Pathology. 2022;84(1): 27‑32

DOI: 10.17116/patol20228401127

Read: 5105 times

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Table of contents

PRIMARY DIFFUSE MENINGEAL MELANOMATOSIS: A LITERATURE REVIEW AND A CASE REPORT
PRIMARY DIFFUSE MENINGEAL MELANOMATOSIS: A LITERATURE REVIEW AND A CASE REPORT

To cite this article:

Sitovskaya DA, Verbitsky OP, Petrova YuA, Sokolova TV, Zabrodskaya YuM. Primary diffuse meningeal melanomatosis: a literature review and a case report. Russian Journal of Archive of Pathology. 2022;84(1):27‑32. (In Russ.)
https://doi.org/10.17116/patol20228401127

Подписка 2026 Архив патологии (Russian Journal of Archive of Pathology)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

Primary melanocytic tumors of the central nervous system (CNS) are extremely rare and account for only 1% of all melanomas and 0.05% of primary brain tumors. In case of diffusely invasive lesions of the pia mater with a tumor of melanocytic origin (without signs of extracranial metastases), the tumors are classified as primary diffuse meningeal melanomatosis (PDMM). The latter is an extremely rare subtype of CNS malignant tumor with an incidence rate of 1 in 20 million people. Despite the development of neuroimaging techniques, today a morphological examination remains the main and most accurate method for verifying CNS melanocytic tumors. The paper describes a fatal case of PMMD manifested as epileptic syndrome, with a rapidly progressive course.

Keywords:

diffuse meningeal melanomatosis
primary
CNS melanocytic tumors

Authors:

Sitovskaya D.A.

Prof. A.L. Polenov Russian Research Institute of Neurosurgery — Branch V.A. Almazov National Medical Research Center of the Ministry of Health of Russia;
City Mariinskaya Hospital

Verbitsky O.P.

City Mariinskaya Hospital

Petrova Yu.A.

City Mariinskaya Hospital

Sokolova T.V.

Prof. A.L. Polenov Russian Research Institute of Neurosurgery — Branch V.A. Almazov National Medical Research Center of the Ministry of Health of Russia

Zabrodskaya Yu.M.

Prof. A.L. Polenov Russian Research Institute of Neurosurgery — Branch V.A. Almazov National Medical Research Center of the Ministry of Health of Russia

Received:

07.09.2021

Accepted:

10.11.2021

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References:

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