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Kuznetsova O.A.

Russian Medical Academy of Continuous Professional Education

Andreeva Yu.Yu.

Russian Medical Academy of Continuous Professional Education

Zavalishina L.E.

Russian Medical Academy of Continuous Professional Education

Demidova I.A.

Moscow City Oncology Hospital No. 62

Gikalo M.B.

Moscow City Oncology Hospital No. 62

Frank G.A.

Russian Medical Academy of Continuous Professional Education

Importance of detecting TRK protein expression and rearrangements in NTRK3 gene in secretory carcinoma of the breast

Authors:

Kuznetsova O.A., Andreeva Yu.Yu., Zavalishina L.E., Demidova I.A., Gikalo M.B., Frank G.A.

More about the authors

Journal: Russian Journal of Archive of Pathology. 2020;82(4): 53‑57

DOI: 10.17116/patol20208204153

Views: 2227

Downloaded: 72

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To cite this article:

Kuznetsova OA, Andreeva YuYu, Zavalishina LE, Demidova IA, Gikalo MB, Frank GA. Importance of detecting TRK protein expression and rearrangements in NTRK3 gene in secretory carcinoma of the breast. Russian Journal of Archive of Pathology. 2020;82(4):53‑57. (In Russ.)
https://doi.org/10.17116/patol20208204153

Подписка 2025 (Russian Journal of Archive of Pathology)
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Secretory carcinoma of the breast is a rare malignant tumor with a relatively favorable prognosis and indolent course. Despite this, it can lead to death or reduce the quality of life. Advances in modern chemotherapy, such as tyrosine kinase inhibitors, can not only extend life, but also reduce the volume of surgery. However, this therapy is not applicable for every patient, but only for those with translocation of the NTRK3 gene.

Keywords:

secretory carcinoma of the brest
NTRK

Authors:

Kuznetsova O.A.

Russian Medical Academy of Continuous Professional Education

Andreeva Yu.Yu.

Russian Medical Academy of Continuous Professional Education

Zavalishina L.E.

Russian Medical Academy of Continuous Professional Education

Demidova I.A.

Moscow City Oncology Hospital No. 62

Gikalo M.B.

Moscow City Oncology Hospital No. 62

Frank G.A.

Russian Medical Academy of Continuous Professional Education

Received:

25.03.2020

Accepted:

20.04.2020

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