Essential cryoglobulinemic vasculitis with the development of mesenteric vascular thrombosis and intestinal gangrene

Severgina L.O.

Sechenov First Moscow State Medical University, Ministry of Health of the Russia, Moscow, Russia

Studennikova V.V.

Sechenov First Moscow State Medical University, Ministry of Health of the Russia, Moscow, Russia

Radenska-Lopovok S.G.

FGBU "Nauchno-issledovatel'skiĭ institut revmatologii im. V.A. Nasonovoĭ" RAMN, Moskva

Kogan E.A.

Nauchnyĭ tsentr akusherstva, ginekologii i perinatologii im. akad. V.I. Kulakova, Moskva

Novikov P.I.

UCH №3 of I.M. Sechenov First Moscow State Medical University, 11, str.5 Rossolimo St., Moscow, Russian Federation, 119021

Korovin I.A.

Sechenov First Moscow State Medical University, Ministry of Health of the Russia, Moscow, Russia

Essential cryoglobulinemic vasculitis with the development of mesenteric vascular thrombosis and intestinal gangrene

Authors:

Severgina L.O., Studennikova V.V., Radenska-Lopovok S.G., Kogan E.A., Novikov P.I., Korovin I.A.

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Journal: Russian Journal of Archive of Pathology. 2018;80(5): 40‑45

DOI: 10.17116/patol20188005140

Downloaded: 71

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To cite this article:

Severgina LO, Studennikova VV, Radenska-Lopovok SG, Kogan EA, Novikov PI, Korovin IA. Essential cryoglobulinemic vasculitis with the development of mesenteric vascular thrombosis and intestinal gangrene. Russian Journal of Archive of Pathology. 2018;80(5):40‑45. (In Russ.)
https://doi.org/10.17116/patol20188005140

Подписка 2025 (Russian Journal of Archive of Pathology)

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The paper describes a case of essential cryoglobulinemia unassociated with hepatitis B and C viruses. The morphological substrate of the disease was exclusively proliferative endothrombovasculitis without destructive changes in the walls of affected vessels. In addition, in the late stage of the disease, there was its unusual manifestation associated with inflammation of the mesentery arteriolar walls and with the formation of occlusive blood clots in their lumens, which led to severe abdominal diseases. The female patient showed a mosaic involvement of the loops of the bowel in the necrotic process as its separate segments, which was associated with damage to a large number of small vessels. The feature of the case is a set of 4 risk factors for a fatal disease outcome, such as age over 65 years, pulmonary, renal, and intestinal lesions.

Keywords:

cryoglobulinemia

essential cryoglobulinemia

vasculitis

mesangiocapillary glomerulonephritis

Authors:

Severgina L.O.

Sechenov First Moscow State Medical University, Ministry of Health of the Russia, Moscow, Russia

Studennikova V.V.

Sechenov First Moscow State Medical University, Ministry of Health of the Russia, Moscow, Russia

Radenska-Lopovok S.G.

FGBU "Nauchno-issledovatel'skiĭ institut revmatologii im. V.A. Nasonovoĭ" RAMN, Moskva

Kogan E.A.

Nauchnyĭ tsentr akusherstva, ginekologii i perinatologii im. akad. V.I. Kulakova, Moskva

Novikov P.I.

UCH №3 of I.M. Sechenov First Moscow State Medical University, 11, str.5 Rossolimo St., Moscow, Russian Federation, 119021

Korovin I.A.

Sechenov First Moscow State Medical University, Ministry of Health of the Russia, Moscow, Russia

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