Лимфогенное метастазирование сарком кости

Авторы:
  • Н. В. Васильев
    Томский НИИ онкологии, Томск, Россия
Журнал: Архив патологии. 2016;78(4): 58-63
Просмотрено: 1509 Скачано: 891
Лимфогенное метастазирование сарком кости достаточно редкое явление - по данным разных авторов, частота метастатического поражения лимфатических узлов составляет от 4 до 11%. Факт обнаружения лимфогенных метастазов при саркомах кости сопряжен с существенным снижением 5-летней выживаемости больных и позволяет классифицировать 4-ю клиническую стадию опухолевого процесса. Факторами риска возникновения лимфогенных метастазов при саркомах кости являются возраст (64 года и более), пол (женский), нозологическая форма (недифференцированная плеоморфная саркома, остеосаркома, хондросаркома), глубина расположения опухоли (мышца, кость), размер первичной опухоли (более 5 см). Предположительно механизм лимфогенного метастазирования костных сарком обусловлен мезенхимально-эпителиальным переходом.
Ключевые слова:
  • саркома кости
  • лимфогенное метастазирование
  • факторы риска возникновения метастазов
  • мезенхимально-эпителиальный переход

КАК ЦИТИРОВАТЬ:

Васильев Н.В. Лимфогенное метастазирование сарком кости. Архив патологии. 2016;78(4):58-63. https://doi.org/10.17116/patol201678458-62

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