Prognostic capabilities of the sofa score in patients with thermal injury

Zhirkova EA, Spiridonova TG, Sachkov AV, et al. . Prognostic capabilities of the sofa score in patients with thermal injury. Russian Journal of Anesthesiology and Reanimatology. 2025;(1):36‑43. (In Russ., In Engl.)
https://doi.org/10.17116/anaesthesiology202501136

Использование инфографики авторами научных работ

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Abstract:

The SOFA scale should be used to predict the outcomes of thermal injury.

OBJECTIVE

To study the possibilities of the SOFA scale in predicting the outcomes of thermal injury in stratification groups of revised Frank index (RFI).

MATERIAL AND METHODS

A retrospective study included 196 patients stratified into 3 groups: RFI≤70 (54 patients, all survived), RFI 71—180 (120 patients: 96 survived, 24 died), RFI≥181 (22 patients, all died). We analyzed SOFA scores within 3 days after injury (SOFA₁, SOFA₂, SOFA₃) and compared in patients of three groups stratified by RFI including between patients with RFI≤70 and survivors with RFI 71—180, survivors and deceased patients with RFI 71—180, with RFI ≥181 and deceased patients with RFI 71—180.

RESULTS

SOFA score within 3 days after injury was significantly higher in deceased patients compared to survivors. After 3 days, SOFA scores were similar (in patients with RFI≤70 and survivors with RFI 71—180, as well as in patients with RFI≥181 and deceased patients with RFI 71—180). Scores were significantly higher in deceased patients with RFI 71—180 compared to survivors for 3 days. ROC analysis of injury outcome depending on SOFA₁, SOFA₂ and SOFA₃ scores showed that all areas under ROC curves (AUCs) exceeded 0.9 with maximum AUC for SOFA₃ (0.960). The cutoff point for SOFA₁-SOFA₃ was SOFA score ≥4. SOFA score ≥4 predicted unfavorable outcomes, SOFA score<4 predicted favorable outcomes.

CONCLUSION

SOFA score characterized clinical severity in RFI-stratified groups. SOFA score ≥4 predicted unfavorable outcomes. Prediction of outcomes after thermal injury using SOFA scale is the most relevant for patients with RFI 71—180.

Keywords:

revised Frank index

RFI

SOFA scale

prognosis of thermal injury outcome

Authors:

Zhirkova E.A.

Sklifosovsky Research Institute for Emergency Care

ORCID: 0000-0002-9862-0229

Spiridonova T.G.

Sklifosovsky Research Institute for Emergency Care

ORCID: 0000-0001-7070-8512

Sachkov A.V.

Sklifosovsky Research Institute for Emergency Care

ORCID: 0000-0003-3742-6374

Eliseenkova E.I.

Sklifosovsky Research Institute for Emergency Care

ORCID: 0000-0002-5070-0908

Borisov I.G.

Sklifosovsky Research Institute for Emergency Care

ORCID: 0000-0002-4895-2444

Medvedev A.O.

Sklifosovsky Research Institute for Emergency Care

ORCID: 0000-0001-7159-7287

Rogal M.L.

Sklifosovsky Research Institute for Emergency Care

ORCID: 0000-0003-1051-7663

Petrikov S.S.

Sklifosovsky Research Institute for Emergency Care;
Russian University of Medicine (Evdokimov Moscow State University of Medicine and Dentistry)

ORCID: 0000-0003-3292-8789

Received:

05.07.2024

Accepted:

16.09.2024

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