Evaluation of the clinical practice of respiratory therapy and outcomes in late preterm (34-36 weeks) with respiratory distress syndrome

Mostovoy A.V.; Karpova A.L.; Volodin N.N.; Petrova A.S.; Mileva O.I.; Zakharova N.I.; Dmitriev A.V.; Ippolitova L.I.

doi:https://doi.org/10.17116/anaesthesiology202104167

Mostovoy A.V.

Kaluga Regional Clinical Hospital

Karpova A.L.

Kaluga Regional Clinical Hospital

Volodin N.N.

Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology

Petrova A.S.

Moscow Regional Perinatal Center

Mileva O.I.

City Clinical Hospital No. 24

Zakharova N.I.

Mytishchi City Clinical Hospital

Dmitriev A.V.

North-Western Association for Parenteral and Enteral Nutrition

ORCID: 0000-0001-6975-6103

Ippolitova L.I.

Voronezh Regional Clinical Hospital No. 1

Evaluation of the clinical practice of respiratory therapy and outcomes in late preterm (34-36 weeks) with respiratory distress syndrome

Authors:

Mostovoy A.V., Karpova A.L., Volodin N.N., Petrova A.S., Mileva O.I., Zakharova N.I., Dmitriev A.V., Ippolitova L.I.

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Journal: Russian Journal of Anesthesiology and Reanimatology. 2021;(4): 67‑72

DOI: 10.17116/anaesthesiology202104167

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To cite this article:

Mostovoy AV, Karpova AL, Volodin NN, et al. . Evaluation of the clinical practice of respiratory therapy and outcomes in late preterm (34-36 weeks) with respiratory distress syndrome. Russian Journal of Anesthesiology and Reanimatology. 2021;(4):67‑72. (In Russ.)
https://doi.org/10.17116/anaesthesiology202104167

Использование инфографики авторами научных работ

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Abstract:

OBJECTIVE

To conduct an epidemiological analysis of the clinical practice of treating premature infants with signs of respiratory distress syndrome (RDS), born at a gestational age of 34⁰/₇-36⁶/₇ weeks, during the first 72 hours of life and clinical situations in which respiratory therapy was required additional therapy with surfactants.

MATERIAL AND METHODS

Over the entire observation period, 27.153 children were born in five perinatal centers of the Central Federal District of the Russian Federation, 1.414 (5.2%) children were late preterm (34⁰/₇-36⁶/₇ weeks), of which 816 infants were admitted to the neonatal intensive care unit (57.7%) and 729 required respiratory therapy (51.6%). For the analysis 120 medical records of premature infants with RDS, born at a gestational age of 34⁰/₇-36⁶/7 weeks, requiring respiratory therapy were selected. Children who received respiratory support due to infectious lung diseases, neurological disorders, and other diseases not associated with RDS were excluded.

RESULTS

The need for substitution therapy with exogenous surfactants was 52.5% (n=63; 95% CI 43.6-61.2) of all RDS cases and 8.6% of the total number of newborns who received respiratory therapy, minimally invasive surfactant administration was performed in 46 children (73.0%).

CONCLUSION

In every seventh late preterm (16.4%) need for respiratory therapy is associated with the development of RDS, of which every second infant needs surfactant administration.

Keywords:

surfactant therapy

respiratory therapy

late premature infants

Authors:

Mostovoy A.V.

Kaluga Regional Clinical Hospital

Karpova A.L.

Kaluga Regional Clinical Hospital

Volodin N.N.

Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology

Petrova A.S.

Moscow Regional Perinatal Center

Mileva O.I.

City Clinical Hospital No. 24

Zakharova N.I.

Mytishchi City Clinical Hospital

Dmitriev A.V.

North-Western Association for Parenteral and Enteral Nutrition

ORCID: 0000-0001-6975-6103

Ippolitova L.I.

Voronezh Regional Clinical Hospital No. 1

Received:

07.05.2021

Accepted:

13.06.2021

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References:

Horbar JD, Carpenter JH, Kenny M, eds. Incidence of respiratory distress syndrome (RDS) in the United States relative to birth weight, which shows it is a disease of premature infants. Vermont Oxford Network 2002 Very Low Birth Weight Database Summary. Burlington, VT: Vermont Oxford Network; 2003.
Consortium on Safe Labor, Hibbard JU, Wilkins I, Sun L, Gregory K, Haberman S, Hoffman M, Kominiarek MA, Reddy U, Bailit J, Branch DW, Burkman R, Gonzalez Quintero VH, Hatjis CG, Landy H, Ramirez M, VanVeldhuisen P, Troendle J, Zhang J. Respiratory morbidity in late preterm births. Journal of the American Medical Association. 2010;304(4):419-425. https://doi.org/10.1001/jama.2010.1015
McIntire DD, Leveno KJ. Neonatal mortality and morbidity rates in late preterm births compared with births at term. Obstetrics and Gynecology. 2008;111(1):35-41. https://doi.org/10.1097/01.AOG.0000297311.33046.73
Teune MJ, Bakhuizen S, Gyamfi Bannerman C, Opmeer BC, van Kaam AH, van Wassenaer AG, Morris JM, Mol BW. A systematic review of severe morbidity in infants born late preterm. American Journal of Obstetrics and Gynecology. 2011;205(4):374.e1-9. https://doi.org/10.1016/j.ajog.2011.07.015
Gyamfi-Bannerman C, Thom EA, Blackwell SC, Tita AT, Reddy UM, Saade GR, Rouse DJ, McKenna DS, Clark EA, Thorp JM Jr, Chien EK, Peaceman AM, Gibbs RS, Swamy GK, Norton ME, Casey BM, Caritis SN, Tolosa JE, Sorokin Y, VanDorsten JP, Jain L; NICHD Maternal-Fetal Medicine Units Network. Antenatal Betamethasone for Women at Risk for Late Preterm Delivery. The New England Journal of Medicine. 2016;374(14): 1311-1320. https://doi.org/10.1056/NEJMoa1516783
Volodin NN, Mostovoy AV, Karpova AL, Petrova AS, Mileva OI, Zakharova NI, Dmitriev AV, Ippolitova LI, Batukhtina NN, Garaeva AS. Therapy of respiratory distress syndrome in late preterm infants: a multi-center pilot study. Pediatriya. Zhurnal im. G.N. Speranskogo. 2020;99(5):85-91. (In Russ.). https://doi.org/10.24110/0031-403X-2020-99-5-85-91
Vedenie novorozhdennykh s respiratornym distress-sindromom. Klinicheskie rekomendatsii pod red. akademika RAN N.N. Volodina. 2016. (In Russ.).
Giannì ML, Roggero P, Piemontese P, Liotto N, Orsi A, Amato O, Taroni F, Morlacchi L, Consonni D, Mosca F. Is nutritional support needed in late preterm infants? BMC Pediatrics. 2015;15:194. https://doi.org/10.1186/s12887-015-0511-8
Delnord M, Zeitlin J. Epidemiology of late preterm and early term births — An international perspective. Seminars in Fetal and Neonatal Medicine. 2019;24(1):3-10. https://doi.org/10.1016/j.siny.2018.09.001
Deshmukh M, Patole S. Antenatal corticosteroids for impending late preterm (34-36+6 weeks) deliveries-A systematic review and meta-analysis of RCTs. PloS One. 2021;16(3):e0248774. https://doi.org/10.1371/journal.pone.0248774
Üstün N, Hocaoğlu M, Turgut A, Arslanoğlu S, Ovalı F. Does antenatal corticosteroid therapy improve neonatal outcomes in late preterm birth? The Journal of Maternal-Fetal and Neonatal Medicine. 2020;1-7. https://doi.org/10.1080/14767058.2020.1808614
Cornette L, Mulder A, Debeer A, Malfilâtre G, Rigo V, Cools F, Danhaive O. Surfactant use in late preterm infants: a survey among Belgian neonatologists. European Journal of Pediatrics. 2021;180(3):885-892. https://doi.org/10.1007/s00431-020-03806-1
Olivier F, Nadeau S, Bélanger S, Julien AS, Massé E, Ali N, Caouette G, Piedboeuf B. Efficacy of minimally invasive surfactant therapy in moderate and late preterm infants: A multicentre randomized control trial. Paediatrics and Child Health. 2017;22(3):120-124. https://doi.org/10.1093/pch/pxx033