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Shelesko E.V.

Burdenko National Medical Research Center of Neurosurgery

Chernikova N.A.

Burdenko National Medical Research Center of Neurosurgery

Kravchuk A.D.

FSAI «National Medical Research Center of Neurosurgery named after acad. N.N. Burdenko» Ministry of Health of Russia

Strunina Yu.V.

Burdenko Neurosurgical Center

Ohlopkov V.A.

FSAI «National Medical Research Center of Neurosurgery named after acad. N.N. Burdenko» Ministry of Health of Russia

Belov A.I.

Burdenko National Scientific and Practical Center for Neurosurgery

Multiple skull base defects: features of pathogenesis, diagnosis and treatment

Authors:

Shelesko E.V., Chernikova N.A., Kravchuk A.D., Strunina Yu.V., Ohlopkov V.A., Belov A.I.

More about the authors

Journal: Burdenko's Journal of Neurosurgery. 2021;85(4): 58‑63

DOI: 10.17116/neiro20218504158

Read: 2069 times

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Table of contents

MULTIPLE SKULL BASE DEFECTS: FEATURES OF PATHOGENESIS, DIAGNOSIS AND TREATMENT
MULTIPLE SKULL BASE DEFECTS: FEATURES OF PATHOGENESIS, DIAGNOSIS AND TREATMENT

To cite this article:

Shelesko EV, Chernikova NA, Kravchuk AD, Strunina YuV, Ohlopkov VA, Belov AI. Multiple skull base defects: features of pathogenesis, diagnosis and treatment. Burdenko's Journal of Neurosurgery. 2021;85(4):58‑63. (In Russ., In Engl.)
https://doi.org/10.17116/neiro20218504158

Подписка 2025 Журнал «Вопросы нейрохирургии» имени Н.Н. Бурденко (Burdenko's Journal of Neurosurgery)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
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Recommended articles:
Basal ence­phalocele complicated by nasal liquorrhea in patients with craniosynostosis. Burdenko's Journal of Neurosurgery. 2025;(4):61-68
Surgical treatment of nasal liquorea in patients with posttraumatic defect of posterior wall of the frontal sinus. Russian Rhinology. 2025;(1):65-71
Abstract:

OBJECTIVE

To determine the risk factors of multiple skull base defects, as well as features of diagnosis and treatment of this pathology.

MATERIAL AND METHODS

A retrospective analysis included 39 patients who underwent surgery for nasal CSF leakage at the Burdenko Neurosurgical Center in 2000—2019. The study recruited patients with multiple simultant skull base defects.

RESULTS

Traumatic defects were observed in 23 (59%) patients, spontaneous defects — in 16 (41%) cases. All patients underwent endoscopic endonasal closure of skull base defects with autografts.

CONCLUSION

Multiple defects are more common in severe traumatic brain injury. The main risk factors of multiple spontaneous defects are female sex and overweight. Adequate diagnosis implies high-resolution CT (slice width 0.5—1 mm), as well as intraoperative control of all suspicious and «weak» areas. Endoscopic endonasal technique is effective and safe for multiple skull base defects (efficiency 97%).

Keywords:

skull base defect
nasal CSF leakage
endoscopic endonasal surgery

Authors:

Shelesko E.V.

Burdenko National Medical Research Center of Neurosurgery

Chernikova N.A.

Burdenko National Medical Research Center of Neurosurgery

Kravchuk A.D.

FSAI «National Medical Research Center of Neurosurgery named after acad. N.N. Burdenko» Ministry of Health of Russia

Strunina Yu.V.

Burdenko Neurosurgical Center

Ohlopkov V.A.

FSAI «National Medical Research Center of Neurosurgery named after acad. N.N. Burdenko» Ministry of Health of Russia

Belov A.I.

Burdenko National Scientific and Practical Center for Neurosurgery

Received:

25.06.2020

Accepted:

28.05.2021

Close metadata

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