Intra-optic nerve and chiasmal abscess caused by methicillin-resistant Staphylococcus aureus (a case report and literature review)

Tropinskaia O.F.; Sharipov O.I.; Ershova O.N.; Kalinin P.L.; Ismailov D.B.

doi:https://doi.org/10.17116/neiro20188206189

Tropinskaia O.F.

NII neĭrokhirurgii im. N.N. Burdenko RAMN, Moskva

Sharipov O.I.

Burdenko Neurosurgical Institute, Moscow, Russian Federation

Ershova O.N.

Federal State Autonomous Institution «N.N. Burdenko National Medical Research Center for Neurosurgery» of the Ministry of Healthcare of the Russian Federation, Moscow, Russia, 125047, Moscow, 4-th Tverskaya-Yamskaya str.,16, Russia

Kalinin P.L.

NII neĭrokhirurgii im. N.N. Burdenko RAMN, Moskva

Ismailov D.B.

Burdenko Neurosurgical Institute, Moscow, Russia

Intra-optic nerve and chiasmal abscess caused by methicillin-resistant Staphylococcus aureus (a case report and literature review)

Authors:

Tropinskaia O.F., Sharipov O.I., Ershova O.N., Kalinin P.L., Ismailov D.B.

More about the authors

Journal: Burdenko's Journal of Neurosurgery. 2018;82(6): 89‑96

DOI: 10.17116/neiro20188206189

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To cite this article:

Tropinskaia OF, Sharipov OI, Ershova ON, Kalinin PL, Ismailov DB. Intra-optic nerve and chiasmal abscess caused by methicillin-resistant Staphylococcus aureus (a case report and literature review). Burdenko's Journal of Neurosurgery. 2018;82(6):89‑96. (In Russ., In Engl.)
https://doi.org/10.17116/neiro20188206189

Подписка 2025 Журнал «Вопросы нейрохирургии» имени Н.Н. Бурденко (Burdenko's Journal of Neurosurgery)

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Abstract:

A 27-year-old immunocompetent male with headache, transient polydipsia, and polyuria suddenly developed visual impairment (predominantly in the left eye) and, 2 days later, left-sided amaurosis. MRI in T1, T2, DWI, and FLAIR modes revealed a space-occupying lesion of the left intracranial optic nerve and chiasm. According to the clinical X-ray picture, malignant chiasmal glioma was suspected; another and less likely variant was lymphoma. An open biopsy of the space-occupying lesion of the chiasmal-sellar region revealed purulent-necrotic masses. Material from the operative wound was positive for a Staphylococcus aureus strain. The polymerase chain reaction of a cerebrospinal fluid sample revealed methicillin-resistant Staphylococcus aureus. The patient underwent systemic and intrathecal antibiotic therapy with linezolid and vancomycin, respectively, with a good clinical effect: there was an improvement in the vision in a right single sighted eye and normalization of the cerebrospinal fluid composition.

Keywords:

optic nerve and chiasm

abscess

methicillin-resistant Staphylococcus aureus

Authors:

Tropinskaia O.F.

NII neĭrokhirurgii im. N.N. Burdenko RAMN, Moskva

Sharipov O.I.

Burdenko Neurosurgical Institute, Moscow, Russian Federation

Ershova O.N.

Kalinin P.L.

NII neĭrokhirurgii im. N.N. Burdenko RAMN, Moskva

Ismailov D.B.

Burdenko Neurosurgical Institute, Moscow, Russia

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