Thyrotropin-producing adenomas and thyrotropic hyperplasia (clinical case reports and the review of the literature)

Astaf'eva L.I.; Kadashev B.A.; Shishkina L.V.; Kalinin P.L.; Kutin M.A.; Sidnevа Yu.G.; Sharipov O.I.

doi:https://doi.org/10.17116/neiro201680382-90

Astaf'eva L.I.

NII neĭrokhirurgii im. N.N. Burdenko RAMN, Moskva

Kadashev B.A.

NII neĭrokhirurgii im. N.N. Burdenko RAMN, Moskva

Shishkina L.V.

Burdenko Neurosurgery Institute, Moscow, Russia

ORCID: 0000-0001-7045-7223

Kalinin P.L.

NII neĭrokhirurgii im. N.N. Burdenko RAMN, Moskva

Kutin M.A.

NII neĭrokhirurgii im. N.N. Burdenko RAMN, Moskva

Sidnevа Yu.G.

Clinical and Research Institute of Emergency Children’s Surgery and Traumatology, Moscow Health Department, Moscow, Russia

Sharipov O.I.

Burdenko Neurosurgical Institute, Moscow, Russian Federation

Thyrotropin-producing adenomas and thyrotropic hyperplasia (clinical case reports and the review of the literature)

Authors:

Astaf'eva L.I., Kadashev B.A., Shishkina L.V., Kalinin P.L., Kutin M.A., Sidnevа Yu.G., Sharipov O.I.

More about the authors

Journal: Burdenko's Journal of Neurosurgery. 2016;80(3): 82‑90

DOI: 10.17116/neiro201680382-90

Read: 8064 times

To cite this article:

Astaf'eva LI, Kadashev BA, Shishkina LV, Kalinin PL, Kutin MA, Sidnevа YuG, Sharipov OI. Thyrotropin-producing adenomas and thyrotropic hyperplasia (clinical case reports and the review of the literature). Burdenko's Journal of Neurosurgery. 2016;80(3):82‑90. (In Russ., In Engl.)
https://doi.org/10.17116/neiro201680382-90

Подписка 2025 Журнал «Вопросы нейрохирургии» имени Н.Н. Бурденко (Burdenko's Journal of Neurosurgery)

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Abstract:

An increased blood level of the thyroid stimulating hormone (TSH) is usually associated with primary hypothyroidism (PHT) but can also be observed in such rare cases as TSH-secreting pituitary tumor. The article describes four clinical cases of elevated TSH blood levels: 1) TSH-secreting pituitary adenoma with hyperthyroidism; 2) TSH-secreting adenoma with hypothyroidism; 3) hormonally inactive pituitary adenoma combined with primary hypothyroidism; 4) reversible thyrotropic hyperplasia. These clinical situations substantiate the importance of considering different diagnoses in a patient with a pituitary gland tumor associated with an increased TSH blood level.

Keywords:

TSH-secreting pituitary adenoma

thyrotropin-producing adenoma

central hyperthyroidism

thyrotropic hyperplasia

primary hypothyroidism

Authors:

Astaf'eva L.I.

NII neĭrokhirurgii im. N.N. Burdenko RAMN, Moskva

Kadashev B.A.

NII neĭrokhirurgii im. N.N. Burdenko RAMN, Moskva

Shishkina L.V.

Burdenko Neurosurgery Institute, Moscow, Russia

ORCID: 0000-0001-7045-7223

Kalinin P.L.

NII neĭrokhirurgii im. N.N. Burdenko RAMN, Moskva

Kutin M.A.

NII neĭrokhirurgii im. N.N. Burdenko RAMN, Moskva

Sidnevа Yu.G.

Clinical and Research Institute of Emergency Children’s Surgery and Traumatology, Moscow Health Department, Moscow, Russia

Sharipov O.I.

Burdenko Neurosurgical Institute, Moscow, Russian Federation

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References:

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