The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-4329
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2026
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Zamergrad M.V.

Levin O.S.

Rossiĭskaia meditsinskaia akademiia poslediplomnogo obrazovaniia

Metavestibular disorders and disorders of higher vestibular function

Authors:

Zamergrad M.V., Levin O.S.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2017;117(6‑2): 11‑15

DOI: 10.17116/jnevro20171176211-15

Read: 2082 times

Download PDF (RU)
Contact the author
Table of contents

METAVESTIBULAR DISORDERS AND DISORDERS OF HIGHER VESTIBULAR FUNCTION
METAVESTIBULAR DISORDERS AND DISORDERS OF HIGHER VESTIBULAR FUNCTION

To cite this article:

Zamergrad MV, Levin OS. Metavestibular disorders and disorders of higher vestibular function. S.S. Korsakov Journal of Neurology and Psychiatry. 2017;117(6‑2):11‑15. (In Russ.)
https://doi.org/10.17116/jnevro20171176211-15

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова. Спецвыпуски (S.S. Korsakov Journal of Neurology and Psychiatry (special issues))
МСФ на ЯМ
Использование инфографики авторами научных работ
Close metadata
Abstract:

Vertigo, instability, oscillopsia and concomitant autonomic disorders are classical and well-known symptoms of vestibular disorders. At the same time, recent studies suggest that there are more complicated vestibular dysfunctions caused by the cortical projections of the vestibular system. The central vestibular system includes parietal temporal cortex and insular, anterior intraparietal sulcus, posterior parietal and medial parts of the superior temporal gyrus, singular gyrus retrosplenial cortex, hippocampus and parahippocampal area. The central part of the vestibular system closely interacts with other afferent systems forming a multisensory structure of higher brain functions. Dysfunctions of higher vestibular function play an important role in the development of clinical syndromes including pusher syndrome, room tilt illusion, unilateral spatial neglect syndrome, impairment of spatial memory and navigation. These syndromes can develop due to the direct damage of the cortical vestibular system or as a result of disconnection between the vestibular cortex and other parts of the sensory cortex.

Keywords:

vestibular system
vestibular cortex
pusher syndrome
room tilt illusion
unilateral spatial neglect syndrome
impairment of spatial memory and navigation

Authors:

Zamergrad M.V.

Levin O.S.

Rossiĭskaia meditsinskaia akademiia poslediplomnogo obrazovaniia

Close metadata

References:

  1. Eulenburg P, Caspers S, Roski C, Eickhoff SB. Meta-analytical definition and functional connectivity of the human vestibular cortex. Neuroimage. 2011;60:162-169. https://doi.org/10.1016/j.neuroimage.2011.12.032
  2. Lopez C, Blanke O. The thalamocortical vestibular system in animals and humans. Brain Res Rev. 2011;67(1-2):119-146. https://doi.org/10.1016/j.brainresrev.2010.12.002
  3. Shinder ME, Taube JS. Differentiating ascending vestibular pathways to the cortex involved in spatial cognition. J Vestib Res. 2010;20:3-23. https://doi.org/10.3233/VES-2010-0344
  4. Björnsdotter M, Löken L, Olausson H, Vallbo A, Wessberg J. Somatotopic organization of gentle touch processing in the posterior insular cortex. J Neurosci. 2009;29:9314-9320. https://doi.org/10.1523/JNEUROSCI.0400-09.2009
  5. Crowe DA, Averbeck BB, Chafee MV. Neural ensemble decoding reveals a correlate of viewer-to object-centered spatial transformation in monkey parietal cortex. J Neurosci. 2008;28(20):5218-5228. https://doi.org/10.1523/JNEUROSCI.5105-07.2008
  6. Bremmer F. Navigation in space — the role of the macaque ventral intraparietal area. J Physiol. 2005;566:29-35. https://doi.org/10.1113/jphysiol.2005.082552
  7. Vann SD, Aggleton JP, Maguire EA. What does the retrosplenial cortex do? Nat Rev Neurosci. 2009;10(11):792-802. https://doi.org/10.1038/nrn2733
  8. McNaughton BL, Battaglia FP, Jensen O, Moser EI, Moser M-B. Path integration and the neural basis of the «cognitive map». Nat Rev Neurosci. 2006;7(8):663-678.
  9. Hafting T, Fyhn M, Molden S, Moser M-B, Moser EI. Microstructure of a spatial map in the entorhinal cortex. Nature. 2005;436:801-806. https://doi.org/10.1038/nature03721
  10. Jacobs J, Weidemann CT, Miller JF, Solway A, Burke JF, Wei XX, Suthana N, Sperling MR, Sharan AD, Fried I, Kahana MJ. Direct recordings of grid-like neuronal activity in human spatial navigation. Nat Neurosci. 2013;16:1188-1190. https://doi.org/10.1038/nn.3466
  11. Clark BJ, Taube JS. Vestibular and attractor network basis of the head direction cell signal in subcortical circuits. Front. Neural Circuits. 2012;6:7. https://doi.org/10.3389/fncir.2012.00007
  12. Russell NA, Horii A, Smith PF, Darlington CL, Bilkey DK. Long-term effects of permanent vestibular lesions on hippocampal spatial firing. J Neurosci. 2003;23:6490-6498.
  13. Fasold O, von Brevern M, Kuhberg M, Ploner CJ, Villringer A, Lempert T, Wenzel R. Human vestibular cortex as identified with caloric stimulation in functional magnetic resonance imaging. Neuroimage. 2002;17:1384-1393. https://doi.org/10.1006/nimg.2002.1241
  14. Dieterich M, Bense S, Lutz S, Drzezga A, Stephan T, Bartenstein P, Brandt T. Dominance for vestibular cortical function in the non-dominant hemisphere. Cereb Cortex. 2003;13:994-1007. https://doi.org/10.1093/cercor/13.9.994
  15. Brandt T, Schautzer F, Hamilton DA, Brüning R, Markowitsch HJ, Kalla R, Darlington C, Smith P, Strupp M. Vestibular loss causes hippocampal atrophy and impaired spatial memory in humans. Brain. 2005; 128(Pt 11):2732-2741.
  16. Moser EI, Kropff E, Moser MB. Place cells, grid cells and the brain’s spatial representation system. Annu Rev Neurosci. 2008;31:69-89. https://doi.org/10.1146/annurev.neuro.31.061307.090723
  17. Fyhn M, Hafting T, Treves A, Moser M-B, Moser EI. Hippocampal remapping and grid realignment in entorhinal cortex. Nature. 2007;446:190-194. https://doi.org/10.1038/nature05601
  18. Pfeiffer BE, Foster DJ. Hippocampal place-cell sequences depict future paths to remembered goals. Nature. 2013;497:74-79. https://doi.org/10.1038/nature12112
  19. Tarnutzer AA, Lee SH, Robinson KA, Kaplan PW, Newman-Toker DE. Clinical and electrographic findings in epileptic vertigo and dizziness: a systematic review. Neurology. 2015;84(15):1595-1604. https://doi.org/10.1212/WNL.0000000000001474
  20. Baier B, Janzen J, Müller-Forell W, Fechir M, Müller N, Dieterich M. Pusher syndrome: its cortical correlate. J Neurol. 2012;259(2):277-283. https://doi.org/10.1007/s00415-011-6173-z
  21. Sierra-Hidalgo F, de Pablo-Fernández E, Herrero-San Martín A, Correas-Callero E, Herreros-Rodríguez J, Romero-Muñoz JP, Martín-Gil L. Clinical and imaging features of the room tilt illusion. J Neurol. 2012;259(12):2555-2564. https://doi.org/10.1007/s00415-012-6536-0
  22. Brandt T, Strupp M, Dieterich M. Towards a concept of disorders of «higher vestibular function». Front Integr Neurosci. 2014;8:47. https://doi.org/10.3389/fnint.2014.00047
  23. Chen XW, Lin CH, Zheng H, Lin ZL. A Chinese patient with pusher syndrome and unilateral spatial neglect syndrome. Can J Neurol Sci. 2014;41(4):493-497.
  24. Honoré J, Saj A, Bernati T, Rousseaux M. The pusher syndrome reverses the orienting bias caused by spatial neglect. Neuropsychologia. 2009;47(3): 634-638. https://doi.org/10.1016/j.neuropsychologia.2008.11.008
  25. Vallar G, Perani D. The anatomy of unilateral neglect after right hemisphere stroke lesions: a clinical CT correlation study in man. Neuropsychologia. 1986;24:609-622. https://doi.org/10.1016/0028-3932(86)90001-1
  26. Brandt T, Dieterich M, Strupp M. Glasauer S. Model approach to neurological variants of visuo-spatial neglect. Biol Cybern. 2012;106:681-690. https://doi.org/10.1007/s00422-012-0517-3
  27. Karnath H-O, Dieterich M. Spatial neglect — a vestibular disorder? Brain. 2006;129:293-305. https://doi.org/10.1093/brain/awh698
  28. Ptak R, Schnider A. The attention network of the human brain: relating structural damage associated with spatial neglect to functional imaging correlates of spatial attention. Neuropsychologia. 2011;49:3063-3070. https://doi.org/10.1016/j.neuropsychologia.2011.07.008
  29. Brandt T, Dieterich M. The vestibular cortex: its locations, functions and disorders. Ann NY Acad Sci. 1999;871:293-312. https://doi.org/10.1111/j.1749-6632.1999.tb09193.x
  30. Vallar G, Bottini G, Rusconi ML. Exploring somatosensory hemineglect by vestibular stimulation. Brain. 1993;116:71-86. https://doi.org/10.1093/brain/116.3.756
  31. Cappa S, Storzi R, Vallar G. Remission of hemineglect and anosognosia during vestibular stimulation. Neuropsychologia. 1987;25:775-782. https://doi.org/10.1016/0028-3932(87)90115-1
  32. López Domínguez JM, Rojas-Marcos I, Sanz Fernández G, Díaz Espejo C. Room tilt illusion: a rare symptom of migraine aura. Neurologia. 2007;22(1):58-60.
  33. Malis DD, Guyot JP. Room tilt illusion as a manifestation of peripheral vestibular disorders. Ann Otol Rhinol Laryngol. 2003;112(7):600-605.
  34. Eimil-Ortiz M, González-Salaices M, Heras IP, Sáiz-Sepúlveda MA, de Miguel CL. Room tilt illusion in superior cerebellar artery stroke: Are we missing the classical neurological examination? Neurol India. 2012;60(4):423-424. https://doi.org/10.4103/0028-3886.100709
  35. Kirsch V, Keeser D, Becker-Bense S, Karali T, Ertl-Wagner B, Brandt T, Dieterich M. Vestibular and visual cortex activity during room tilt illusion. J Neurol. 2017. https://doi.org/10.1007/s00415-017-8457-4
  36. Brandt T. Cortical matching of visual and vestibular 3-D coordinate maps. Ann Neurol. 1997;42:983-984. https://doi.org/10.1002/ana.410420624
  37. Schautzer F, Hamilton D, Kalla R, Strupp M, Brandt T. Spatial memory deficits in patients with chronic bilateral vestibular failure. Ann N Y Acad Sci. 2003;1004:316-324.
  38. Guidetti G, Monzani D, Trebbi M, Rovatti V. Impaired navigation skills in patients with psychological distress and chronic peripheral vestibular hypofunction without vertigo. Acta Otorhinolaryngol Ital. 2008;28(1):21-25.
  39. Hüfner K, Hamilton DA, Kalla R, Stephan T, Glasauer S, Ma J, Brüning R, Markowitsch HJ, Labudda K, Schichor C, Strupp M, Brandt T. Spatial memory and hippocampal volume in humans with unilateral vestibular deafferentation. Hippocampus. 2007;17(6):471-485.
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.