Neurotropic, anti-inflammatory and antitumor properties of hopantenic acid: a chemoinformatic analysis of its molecule

Gromova O.A.; Torshin I.Iu.; Limanova O.A.; Gromov A.N.; Fedotova L.E.; Rudakov K.V.

doi:https://doi.org/10.17116/jnevro20151155261-71

Gromova O.A.

Rossiĭskiĭ satellitnyĭ tsentr instituta mikroélementov IuNESKO;
Laboratoriia vychislitel'noĭ i sistemnoĭ biologii VTs RAN im. A.A. Dorodnitsyna;
kafedra farmakologii i klinicheskoĭ farmakologii Ivanovskoĭ gosudarstvennoĭ meditsinskoĭ akademii

ORCID: 0000-0002-7663-710X

Torshin I.Iu.

Rossiĭskiĭ satellitnyĭ tsentr instituta mikroélementov IuNESKO;
Laboratoriia vychislitel'noĭ i sistemnoĭ biologii VTs RAN im. A.A. Dorodnitsyna

Limanova O.A.

Ivanovo State Medical Academy, Ivanovo, Moscow Institute of Physics and Technology, Moscow

Gromov A.N.

Ivanovo State Medical Academy, Ivanovo, Moscow Institute of Physics and Technology, Moscow

Fedotova L.E.

Ivanovo State Medical Academy, Ivanovo

Rudakov K.V.

Rossiĭskiĭ satellitnyĭ tsentr instituta mikroélementov IuNESKO

Neurotropic, anti-inflammatory and antitumor properties of hopantenic acid: a chemoinformatic analysis of its molecule

Authors:

Gromova O.A., Torshin I.Iu., Limanova O.A., Gromov A.N., Fedotova L.E., Rudakov K.V.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2015;115(5‑2): 61‑71

DOI: 10.17116/jnevro20151155261-71

Read: 7519 times

Download PDF (RU)

Contact the author

Table of contents

To cite this article:

Gromova OA, Torshin IIu, Limanova OA, Gromov AN, Fedotova LE, Rudakov KV. Neurotropic, anti-inflammatory and antitumor properties of hopantenic acid: a chemoinformatic analysis of its molecule. S.S. Korsakov Journal of Neurology and Psychiatry. 2015;115(5‑2):61‑71. (In Russ.)
https://doi.org/10.17116/jnevro20151155261-71

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова. Спецвыпуски (S.S. Korsakov Journal of Neurology and Psychiatry (special issues))

Использование инфографики авторами научных работ

Close metadata

Abstract:

Hopantenic acid is a well-known nootropic drug similar in its chemical structure to pantothenic acid (vitamin B5). Neurotropic effects of hopantenic acid act through binding with delta- and kappa opioid receptors, modulation of acetylcholine secretion and relationship with dopamine receptors. Besides neurotropic effects, hopantenic acid may modulate the metabolism of prostaglandins, steroids and have antitumor effects.

Keywords:

hopantenic acid

chemoinformatics

pantocalcin

Authors:

Gromova O.A.

ORCID: 0000-0002-7663-710X

Torshin I.Iu.

Rossiĭskiĭ satellitnyĭ tsentr instituta mikroélementov IuNESKO;
Laboratoriia vychislitel'noĭ i sistemnoĭ biologii VTs RAN im. A.A. Dorodnitsyna

Limanova O.A.

Ivanovo State Medical Academy, Ivanovo, Moscow Institute of Physics and Technology, Moscow

Gromov A.N.

Ivanovo State Medical Academy, Ivanovo, Moscow Institute of Physics and Technology, Moscow

Fedotova L.E.

Ivanovo State Medical Academy, Ivanovo

Rudakov K.V.

Rossiĭskiĭ satellitnyĭ tsentr instituta mikroélementov IuNESKO

Close metadata