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Ovchinnikov A.Iu.

Kafedra otorinolaringologii fakul'teta poslediplomnogo obrazovaniia Moskovskogo gosudarstvennogo meditsinskogo stomatologicheskogo universiteta

Miroshnichenko N.A.

Evdokimov Moscow State Medical Stomatological University, Moscow, Russia, 127473

Mitiuk A.M.

Kafedra otorinolaringologii fakul'teta postdiplomnogo obrazovaniia Moskovskogo gosudarstvennogo mediko-stomatologicheskogo universiteta im. A.I. Evdokimova

Ryabinin V.A.

A.I. Evdokimov Moscow State Medical Stomatological University, Mosco, Russia, 127473

Gorban D.G.

Moskovskiĭ nauchno-prakticheskiĭ tsentr otorinolaringologii Departamenta zdravookhraneniia Moskvy

The new possibilities for the treatment of chronic cough associated with postnasal drip

Authors:

Ovchinnikov A.Iu., Miroshnichenko N.A., Mitiuk A.M., Ryabinin V.A., Gorban D.G.

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Journal: Russian Bulletin of Otorhinolaryngology. 2017;82(2): 60‑64

DOI: 10.17116/otorino201782260-64

Views: 31294

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To cite this article:

Ovchinnikov AIu, Miroshnichenko NA, Mitiuk AM, Ryabinin VA, Gorban DG. The new possibilities for the treatment of chronic cough associated with postnasal drip. Russian Bulletin of Otorhinolaryngology. 2017;82(2):60‑64. (In Russ.)
https://doi.org/10.17116/otorino201782260-64

Подписка 2025 (Russian Bulletin of Otorhinolaryngology)
 
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Cough is considered to be one of the leading clinical symptoms associated with the pathological changes in the respiratory system. Notwithstanding a great variety of therapeutic pharmaceutical products possessed of the antitussive action, physicians tend the give preference to the preparations producing the combined effect. The present article reports the results of the clinical study designed to evaluate the effectiveness and safety of the application of rengalin exhibiting the combined antitussive, anti-inflammatory, and broncholytic action in the patients presenting with the postnasal drip syndrome. The comparison of the therapeutic effects of rengalin with those of other therapeutic modalities frequently employed for the management of postnasal drip give evidence of the high efficiency of this product for the optimization of the treatment of this condition and the associated chronic cough.

Keywords:

rengalin
postnasal drip
chronic cough

Authors:

Ovchinnikov A.Iu.

Kafedra otorinolaringologii fakul'teta poslediplomnogo obrazovaniia Moskovskogo gosudarstvennogo meditsinskogo stomatologicheskogo universiteta

Miroshnichenko N.A.

Evdokimov Moscow State Medical Stomatological University, Moscow, Russia, 127473

Mitiuk A.M.

Kafedra otorinolaringologii fakul'teta postdiplomnogo obrazovaniia Moskovskogo gosudarstvennogo mediko-stomatologicheskogo universiteta im. A.I. Evdokimova

Ryabinin V.A.

A.I. Evdokimov Moscow State Medical Stomatological University, Mosco, Russia, 127473

Gorban D.G.

Moskovskiĭ nauchno-prakticheskiĭ tsentr otorinolaringologii Departamenta zdravookhraneniia Moskvy

List of references:

  1. Sinopal'nikov AI, Klyachkina IL. Kashel'. M.: MIA; 2013. (In Russ.).
  2. ERS guidelines on the assessment of cough. ERS Task Force. Morice A.H., Fontana G.A., Belvisi M.G. et al. Eur Respir J. 2007;29:1256-1276.
  3. Sergeeva SA, Kovaleva VL, Zak MS, Epshtein OI. Issledovanie protivokashlevoi aktivnosti sverkhmalykh doz antitel k bradikininu u morskikh svinok. IX Rossiiskii natsional'nyi kongress «Chelovek i lekarstvo», materialy. M. 2002;6:94-94. (In Russ.).
  4. Chuchalin AG, Abrosimov VN. Kashel'. Izd 2. M.: Ekho; 2012. (In Russ.).
  5. Instruktsiya po meditsinskomu primeneniyu preparata Rengalin v baze Gosudarstvennogo reestra lekarstvennykh sredstv. (In Russ.).
  6. Kovaleva VL, Zak MS, Epshtein OI, Sergeeva SA. Izuchenie vliyaniya svermalykh doz antitel k gistaminu na kontrakturu gladkikh myshts izolirovannoi trakhei morskoi svinki. X Rossiiskii natsional'nyi kongress «Chelovek i lekarstvo», materialy. M. 2003. (In Russ.).
  7. Kovaleva VL, Zak MS, Epshtein OI, Sergeeva SA. Issledovanie vliyaniya sverkhmalykh doz antitel k bradikininu na kashlevoi refleks u intaktnykh i immunizirovannykh morskikh svinok. X Rossiiskii natsional'nyi kongress «Chelovek i lekarstvo», materialy. M. 2003. (In Russ.).
  8. Peskova Yu. Umenie upravlyat' kashlem neobkhodimo lyubomu prakticheskomu vrachu. Meditsinskii vestnik. 2016;8(729):16. (In Russ.).
  9. Kovaleva VL, Zak MS, Sergeeva SА, Epstein OI. Antitussive activity of antibodies in ultralow doses. XIV World Congress of Pharmacology «The New Century of Pharmacology», San Francisco, California, July 7—12, 2002. Abstract Volume. Pharmacologist. 2002;44(2)(suppl 1):227-228.
  10. Karpova EP. Novoe reshenie problemy vybora preparata dlya patogeneticheski obosnovannoi terapii kashlya u detei. Voprosy prakticheskoi pediatrii. 2015;10(6):61-67. (In Russ.).
  11. Akopov AL, Aleksandrova EB, Il'kovich MM, Petrov DV, Trofimov VI. Rengalin — novyj jeffektivnyj i 'ezopasnyj preparat v lechenii kashlja. Rezul'taty mnogocentrovogo sravnitel'nogo randomizirovannogo klinicheskogo issledovanija u bol'nyh s ostrymi respiratornymi infekcijami. Antibiotiki i himioterapija. 2015;60:19-26. (In Russ.).

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