The modern strategies for the treatment of allergic rhinitis

Nosulia E.V.; Kim I.A.

doi:https://doi.org/10.17116/otorino201681274-76

Nosulia E.V.

Kim I.A.

Kafedra otorinolaringologii RMAPO, Moskva

The modern strategies for the treatment of allergic rhinitis

Authors:

Nosulia E.V., Kim I.A.

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Journal: Russian Bulletin of Otorhinolaryngology. 2016;81(2): 74‑76

DOI: 10.17116/otorino201681274-76

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To cite this article:

Nosulia EV, Kim IA. The modern strategies for the treatment of allergic rhinitis. Russian Bulletin of Otorhinolaryngology. 2016;81(2):74‑76. (In Russ.)
https://doi.org/10.17116/otorino201681274-76

Подписка 2026 Вестник оториноларингологии (Russian Bulletin of Otorhinolaryngology)

Использование инфографики авторами научных работ

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Abstract:

The present literature review had the objective to analyze the published data concerning the effectiveness of intranasal administration of antihistamine preparations and intranasal glucocorticoids for the treatment of allergic rhinitis. Special emphasis is placed on the clinical significance and the further prospects for the application of a fixed combination of these medications including azelastineplusmometasonefuroateas the first choice therapy of moderately severe and severe manifestations of allergic rhinitis.

Keywords:

allergic rhinitis

azelastine

mometasonefuroate

Authors:

Nosulia E.V.

Kim I.A.

Kafedra otorinolaringologii RMAPO, Moskva

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References:

Bellanti JA, Wallerstedt DB. Allergic rhinitis update: Epidemiology and natural history. Allergy Asthma Proc. 2000;21(6):367-370.
Skoner DP. Allergic rhinitis: definition, epidemiology, pathophysiology, detection, and diagnosis. J Allergy Clin Immunol. 2001;108(1 suppl):2-8.
Sibbald B, Rink E. Epidemiology of seasonal and perennial rhinitis: clinical presentation and medical history. Thorax. 1991;46(12):895-901.
Il'ina N.I., Pol'der S.A. Kruglogodichnyi allergicheskii rinit. Consillium medicum. 2001;3:8.
Il'ina N.I. Epidemiologiya allergicheskogo rinita. Rossiiskayarinologiya. 1999;1:23-24.
Gregory C, Cifaldi M, Tanner LA. Targeted intervention programs: creating a customized practice model to improve the treatment of allergic rhinitis in a managed care population. Am J Manag Care. 1999;5:485-496.
Bousquet J, Khaltaev N, Cruz AA, Denburg J, Fokkens WJ, Togias A, Zuberbier T, Baena-Cagnani CE, Canonica GW, van Weel C, Agache I, Aït-Khaled N, Bachert C, Blaiss MS. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen). Allergy. 2008;63(suppl 86):8-160. doi: 10.1111/j.1398-9995.2007.01620.x.
Thomas KE, Ollier S, Ferguson H, Davies RJ. The effect of intranasal azelastine, Rhinolast, on nasal airways obstruction and sneezing following provocation testing with histamine and allergen. Clin and Exp Allergy. 1992;22:642-647.
Lumry W, Prenner B, Corren J, Wheeler W. Efficacy and safety of azelastine nasal spray at a dose of 1 spray per nostril twice daily. Ann Allergy Asthma Immunol. 2007;99(3):267-272.
Bernstein JA. Azelastine hydrochloride: a review of pharmacology, pharmacokinetics, clinical efficacy and tolerability. Curr Med Res Opin. 2007;23(10):2441-2452.
Meltzer EO, Jalowayski AA, Orgel HA, Harris AG. Subjective and objective assessments in patients with seasonal allergic rhinitis: effects of therapy with mometasone furoate nasal spray. J Allergy Clin Immunol. 1998;102(1):39-49.
Minshall E, Ghaffar O, Cameron L, O’Brien F, Quinn H, Rowe-Jones J, Davies RJ, Prior A, Lund VJ, Mackay IS, Nolop K, Lutsky B, Durham SR, Hamid Q. Assessment by nasal biopsy of long-term use of mometasone furoate aqueous nasal spray (Nasonex) in the treatment of perennial rhinitis. Otolaryngol Head Neck Surg. 1998;118(5):648-654.
Frieri M, Therattil J, Chavarria V, Cosachov J, Kumar NS, Wang SF, Sansone G, Etzel J, Dellevecchia D, Zitt M, Mesarina-Wicki B, Nolop KB. Effect of mometasone furoate on early and late phase inflammation in patients with seasonal allergic rhinitis. Ann Allergy Asthma Immunol. 1998;81(5):431-437.
Ratner PH, Hampel F, Van Bavel J, Amar NJ, Daftary P, Wheeler W, Sacks H. Combination therapy with azelastine hydrochloride nasal spray and fluticasone propionate nasal spray in the treatment of patients with seasonal allergic rhinitis. Ann Allergy Asthma Immunol. 2008;100(1):74-81. doi: 10.1016/S1081-1206(10)60408-5.
Hampel FC, Ratner PH, Van Bavel J, Amar NJ, Daftary P, Wheeler W, Sacks H. Double-blind, placebo-controlled study of azelastine and fluticasone in a single nasal spray delivery device. Ann Allergy Asthma Immunol. 2010;105(2):168-173. doi: 10.1016/j.anai.2010.06.008.
Wolthers OD. New patents of fixed combinations of nasal antihistamines and corticosteroids in allergic rhinitis. Recent Pat Inflamm Allergy Drug Discov. 2013;7(3):223-228.