The objective of the present retrospective study was to estimate the effectiveness of the treatment of the patients presenting with tympanophonia taking into consideration their specific psychoemotional status. The study included a total of 56 patients (25 women and 31 men) at the age from 18 to 42 years. They were allocated to 4 groups based on the results of relevant testing procedures. The patients exhibiting moderate emotional lability were treated with choline alfoscerate and vitamins of group B supplemented by tanakan. Those characterized by enhanced emotional lability and sleep disorders were given psychotherapy. Hirudotherapy was prescribed to 10 patients to improve venous outflow. The follow-up testing has demonstrated that the best results were achieved in the patients receiving psychotherapy despite minimal changes of the results of acoustimetry. The patients with the duration of the disease described themselves as perfectly healthy after the course of therapy with the use of tanakan. The severity of tympanophonia was reduced more than by half in 73% of the patients and totally disappeared in 27% of those suffering chronic tympanophonia of moderate intensity. In nine of the 10 patients given hirudotherapy, tympanophonia was reduced by one third on the average. It is concluded that correction of the psychoemotional status significantly improves the quality of life in the patients with tympanophonia. The introduction of tanakan into combined treatment of this condition makes it possible to reduce the intensity of tympanophonia and improve its psychoemotional background as was described in an earlier work of N.N. Yakhno and co-workers.