Venous blood flow in ocular vessels of patients with active retinopathy of prematurity

Trifanenkova I.G.

Kaluga branch of S.N. Fyodorov National Medical Research Center «MNTK «Eye Microsurgery»

Tereshchenko A.V.

Kaluga branch of S.N. Fyodorov National Medical Research Center «MNTK «Eye Microsurgery»

Erokhina E.V.

Kaluga Branch of the S.N. Fedorov National Medical Research Center «MNTK «Eye Microsurgery»

Venous blood flow in ocular vessels of patients with active retinopathy of prematurity

Authors:

Trifanenkova I.G., Tereshchenko A.V., Erokhina E.V.

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Journal: Russian Annals of Ophthalmology. 2021;137(4): 65‑71

DOI: 10.17116/oftalma202113704165

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To cite this article:

Trifanenkova IG, Tereshchenko AV, Erokhina EV. Venous blood flow in ocular vessels of patients with active retinopathy of prematurity. Russian Annals of Ophthalmology. 2021;137(4):65‑71. (In Russ.)
https://doi.org/10.17116/oftalma202113704165

Подписка 2025-2 (Russian Annals of Ophthalmology)

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PURPOSE

To study the characteristics of venous circulation in the eyes with retinopathy of prematurity (ROP) observed in examination of blood flow in the central retinal vein and superior orbital vein in patients with different forms, stages and state of the disease.

MATERIAL AND METHODS

Color duplex scanning of the central retinal vein and superior orbital vein was performed using color Doppler imaging and pulsed Doppler sonography in 55 premature babies (55 eyes) with active ROP and 8 premature babies (8 eyes) with no signs of ROP. All babies included in the study were born at 25—32 weeks of gestation, their birth weight was 680—1760 g.

RESULTS

A characteristic feature of hemodynamic parameters in the central retinal vein at stages 1—3 of active ROP was a decrease in both the maximum and minimum blood flow velocities (V_max and V_min), indicating a serious disorder of ocular hemodynamics in this category of patients. An increase in V_max in the central retinal vein was recorded for patients with aggressive posterior ROP, which occurs in response to venous stasis that is common in this form of the disease. The performed statistical assessment of the prognostic significance of hemodynamic parameters of the central retinal vein in relation to the type of active ROP revealed a high information content of V_min, which is promising for early detection of unfavorable course of the disease helping to ensure timely treatment. The blood flow in the superior orbital vein showed distinctive absence of any correlations with the course of the disease, disallowing any immediate conclusions on the informativeness and predictive value of its parameters.

CONCLUSION

The revealed features of venous blood flow in patients with active ROP help expand the understanding of vascular changes in this pathology, and can also be applied in clinical practice to improve the accuracy of predicting the course of the disease.

Keywords:

retinopathy of prematurity

venous blood flow

central retinal vein

superior orbital vein

Authors:

Trifanenkova I.G.

Kaluga branch of S.N. Fyodorov National Medical Research Center «MNTK «Eye Microsurgery»

Tereshchenko A.V.

Kaluga branch of S.N. Fyodorov National Medical Research Center «MNTK «Eye Microsurgery»

Erokhina E.V.

Kaluga Branch of the S.N. Fedorov National Medical Research Center «MNTK «Eye Microsurgery»

Received:

16.02.2021

Accepted:

14.05.2021

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