Successful treatment for cryptococcal meningoencephalitis complicated by cerebral salt-wasting syndrome in a patient with chronic lymphocytic leukemia: A clinical case

Potapenko V.G.; Konovalenko I.B.; Oksema Е.V.; Filippova L.N.; Dulaeva E.N.; Derevyannykh N.А.; Krasnoruzhskiĭ A.I.; Klimovich A.V.; Klimko N.N.; Medvedeva N.V.

doi:https://doi.org/10.17116/terarkh2015871199-102

Potapenko V.G.

City Clinical Hospital Thirty-One, Saint Petersburg, Russia;
Acad. I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Health of Russia, Saint Petersburg, Russia

Konovalenko I.B.

City Clinical Hospital Thirty-One, Saint Petersburg, Russia

Oksema Е.V.

City Clinical Hospital Thirty-One, Saint Petersburg, Russia

Filippova L.N.

City Clinical Hospital Thirty-One, Saint Petersburg, Russia

Dulaeva E.N.

City Clinical Hospital Thirty-One, Saint Petersburg, Russia

Derevyannykh N.А.

City Clinical Hospital Thirty-One, Saint Petersburg, Russia

Krasnoruzhskiĭ A.I.

Sankt-Peterburgskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. I.P. Pavlova;
Gorodskaia bol'nitsa #31 im. Ia.M. Sverdlova, Sankt-Peterburg

Klimovich A.V.

Sankt-Peterburgskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. I.P. Pavlova;
Gorodskaia bol'nitsa #31 im. Ia.M. Sverdlova, Sankt-Peterburg

Klimko N.N.

P.N. Kashkin Research Institute of Medical Mycology, I.I. Mechnikov North-Western State Medical University, Ministry of Health of Russia, Saint-Petersburg, Russian

Medvedeva N.V.

City Clinical Hospital Thirty-One, Saint Petersburg, Russia

Successful treatment for cryptococcal meningoencephalitis complicated by cerebral salt-wasting syndrome in a patient with chronic lymphocytic leukemia: A clinical case

Authors:

Potapenko V.G., Konovalenko I.B., Oksema Е.V., Filippova L.N., Dulaeva E.N., Derevyannykh N.А., Krasnoruzhskiĭ A.I., Klimovich A.V., Klimko N.N., Medvedeva N.V.

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Journal: Therapeutic Archive. 2015;87(11): 99‑102

DOI: 10.17116/terarkh2015871199-102

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To cite this article:

Potapenko VG, Konovalenko IB, Oksema ЕV, et al. . Successful treatment for cryptococcal meningoencephalitis complicated by cerebral salt-wasting syndrome in a patient with chronic lymphocytic leukemia: A clinical case. Therapeutic Archive. 2015;87(11):99‑102. (In Russ.)
https://doi.org/10.17116/terarkh2015871199-102

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Abstract:

Cryptococcus neoformans is a common agent of fungal meningoencephalitis in immunocompromised patients. Cerebral salt-wasting syndrome is one of the rare causes of severe hyponatremia in patients with CNS diseases. The paper describes the first clinical case of a patient, whose onset of chronic lymphocytic leukemia was complicated by cryptococcal meningoencephalitis presenting with mental disorders and severe electrolytic imbalance. Antifungal treatment with amphotericin B and fluconazole could alleviate an infectious process and metabolic disturbances.

Keywords:

Cryptococcus

meningoencephalitis

cerebral salt-wasting syndrome

amphotericin B

chronic lymphocytic leukemia

Authors:

Potapenko V.G.

City Clinical Hospital Thirty-One, Saint Petersburg, Russia;
Acad. I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Health of Russia, Saint Petersburg, Russia

Konovalenko I.B.

City Clinical Hospital Thirty-One, Saint Petersburg, Russia

Oksema Е.V.

City Clinical Hospital Thirty-One, Saint Petersburg, Russia

Filippova L.N.

City Clinical Hospital Thirty-One, Saint Petersburg, Russia

Dulaeva E.N.

City Clinical Hospital Thirty-One, Saint Petersburg, Russia

Derevyannykh N.А.

City Clinical Hospital Thirty-One, Saint Petersburg, Russia

Krasnoruzhskiĭ A.I.

Sankt-Peterburgskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. I.P. Pavlova;
Gorodskaia bol'nitsa #31 im. Ia.M. Sverdlova, Sankt-Peterburg

Klimovich A.V.

Sankt-Peterburgskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. I.P. Pavlova;
Gorodskaia bol'nitsa #31 im. Ia.M. Sverdlova, Sankt-Peterburg

Klimko N.N.

P.N. Kashkin Research Institute of Medical Mycology, I.I. Mechnikov North-Western State Medical University, Ministry of Health of Russia, Saint-Petersburg, Russian

Medvedeva N.V.

City Clinical Hospital Thirty-One, Saint Petersburg, Russia

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