Significance of surfactant proteins in the diagnosis of therapeutic diseases

Kovalkova N.A.; Ragino Yu.I.; Logvinenko N.I.; Merekina E.S.; Voevoda M.I.

doi:https://doi.org/10.17116/terarkh2015871115-119

Kovalkova N.A.

Research Institute of Therapy and Preventive Medicine, Siberian Branch, Russian Academy of Medical Sciences, Novosibirsk, Russia

Ragino Yu.I.

Research Institute of Therapy and Preventive Medicine, Siberian Branch, Russian Academy of Medical Sciences, Novosibirsk, Russia

Logvinenko N.I.

Research Institute of Therapy and Preventive Medicine, Siberian Branch, Russian Academy of Medical Sciences, Novosibirsk, Russia

Merekina E.S.

Research Institute of Therapy and Preventive Medicine, Siberian Branch, Russian Academy of Medical Sciences, Novosibirsk, Russia

Voevoda M.I.

Research Institute of Therapy and Prophylactic Medicine, Siberian Branch of the Russian Academy of Medical Sciences;
City Clinical Hospital No1, Novosibirsk, Russia

Significance of surfactant proteins in the diagnosis of therapeutic diseases

Authors:

Kovalkova N.A., Ragino Yu.I., Logvinenko N.I., Merekina E.S., Voevoda M.I.

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Journal: Therapeutic Archive. 2015;87(1): 115‑119

DOI: 10.17116/terarkh2015871115-119

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To cite this article:

Kovalkova NA, Ragino YuI, Logvinenko NI, Merekina ES, Voevoda MI. Significance of surfactant proteins in the diagnosis of therapeutic diseases. Therapeutic Archive. 2015;87(1):115‑119. (In Russ.)
https://doi.org/10.17116/terarkh2015871115-119

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Abstract:

The lung provides not only respiration, but also the functioning of innate immunity mechanisms. The hydrophilic proteins SP-A and SP-D are responsible for the regulation of the latter. In the literature, there is evidence for elevated serum SP-A and SP-D levels in respiratory diseases accompanied by enhanced mucosal inflammation of the lung or its parenchymal injury and their association with age and cardiovascular diseases has been recently found. Studies of the efficiency of using SP-A and SP-D as specific markers for inflammatory lung diseases are presently worthwhile.

Keywords:

surfactant protein

SP-A and SP-D

diagnosis of therapeutic diseases

Authors:

Kovalkova N.A.

Research Institute of Therapy and Preventive Medicine, Siberian Branch, Russian Academy of Medical Sciences, Novosibirsk, Russia

Ragino Yu.I.

Research Institute of Therapy and Preventive Medicine, Siberian Branch, Russian Academy of Medical Sciences, Novosibirsk, Russia

Logvinenko N.I.

Research Institute of Therapy and Preventive Medicine, Siberian Branch, Russian Academy of Medical Sciences, Novosibirsk, Russia

Merekina E.S.

Research Institute of Therapy and Preventive Medicine, Siberian Branch, Russian Academy of Medical Sciences, Novosibirsk, Russia

Voevoda M.I.

Research Institute of Therapy and Prophylactic Medicine, Siberian Branch of the Russian Academy of Medical Sciences;
City Clinical Hospital No1, Novosibirsk, Russia

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