Optimization of an approach to solving the problem of a barren marriage in secretory azoospermic men

Sukhikh G.T.; Gamidov S.I.; Popova A.Iu.; Ovchinnikov R.I.; Shcherbakov D.V.; Krasova O.M.; Izhbaev S.Kh.; Shchegolev A.I.; Dubova E.A.; Mishieva N.G.; Abubakirov A.N.; Kamaletdinov N.S.

doi:https://doi.org/

Sukhikh G.T.

Kafedra akusherstva, ginekologii, perinatologii i reproduktologii fakul'teta poslevuzovskogo professional'nogo obrazovaniia vracheĭ Moskovskoĭ meditsinskoĭ akademii im. I.M. Sechenova

Gamidov S.I.

Kafedra urologii Rossiĭskogo gosudarstvennogo meditsinskogo universiteta, Moskva

Popova A.Iu.

Nauchnyĭ tsentr akusherstva, ginekologii i perinatologii im. V.I. Kulakova Minzdravsotsrazvitiia RF, Moskva

Ovchinnikov R.I.

FGBU "Nauchnyĭ tsentr akusherstva, ginekologii i perinatologii im. akad. V.I. Kulakova" Minzdrava RF, Moskva

Shcherbakov D.V.

Otdelenie andrologii i urologii

Krasova O.M.

Kafedra urologii Rossiĭskogo natsional'nogo issledovatel'skogo meditsinskogo universiteta im. N.I. Pirogova Minzdrava Rossii

Izhbaev S.Kh.

Kafedra urologii Rossiĭskogo natsional'nogo issledovatel'skogo meditsinskogo universiteta im. N.I. Pirogova Minzdrava Rossii

Shchegolev A.I.

Institut khirurgii im. A.V. Vishnevskogo, Moskva

ORCID: 0000-0002-2111-1530

Dubova E.A.

Institut khirurgii im. A.V. Vishnevskogo, Moskva

Mishieva N.G.

FGU "Nauchnyĭ tsentr akusherstva, ginekologii i perinatologii im. akad. V.I. Kulakova" Minzdravsotsrazvitiia Rossii, Moskva

Abubakirov A.N.

FGU "Nauchnyĭ tsentr akusherstva, ginekologii i perinatologii im. akad. V.I. Kulakova" Minzdravsotsrazvitiia Rossii, Moskva

Kamaletdinov N.S.

1-e ginekologicheskoe otdelenie (reproduktsii) Nauchnogo tsentra akusherstva, ginekologii i perinatologii im. akad. V.I. Kulakova Minzdrava Rossii, Moskva

Optimization of an approach to solving the problem of a barren marriage in secretory azoospermic men

Authors:

Sukhikh G.T., Gamidov S.I., Popova A.Iu., Ovchinnikov R.I., Shcherbakov D.V., Krasova O.M., Izhbaev S.Kh., Shchegolev A.I., Dubova E.A., Mishieva N.G., Abubakirov A.N., Kamaletdinov N.S.

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Journal: Therapeutic Archive. 2013;85(10): 70‑75

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To cite this article:

Sukhikh GT, Gamidov SI, Popova AIu, et al. Optimization of an approach to solving the problem of a barren marriage in secretory azoospermic men. Therapeutic Archive. 2013;85(10):70‑75. (In Russ.)

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Abstract:

Aim. To compare the efficiency of using different interventional procedures for a barren marriage in case of secretory azoospermia (SAS). Subjects and methods. The trial enrolled 110 patients aged 25 to 54 years with SAS. The levels of sexual hormones were determined; ovarian punch biopsy was performed. Results. Decreased volume of the ovaries was noted in 85.3% of the patients; diffuse or focal changes in their parenchyma were seen in 65.7%. There was an increase of follicle-stimulating hormone levels and a reduction in testosterone ones. Hyperestrogenemia was identified in 26.5% of the patients. The level of inhibin B was lower in all the patients. The efficiency of standard testicular sperm extraction for cryopreservation was achieved in 28.7% of the patients and that of a microsurgical technique was in 56.7%. The wives of 37 out of the 57 patients included in an assisted reproductive technology program were more than 12 weeks pregnant after 95 intracytoplasmic sperm injection cycles. Conclusion. The microsurgical technique is most effective in achieving the successful treatment of patients with azoospermia in order to prevent male infertility.

Keywords:

barren marriage

secretory azoospermia

microsurgical technique

intracytoplasmic sperm injection

barren marriage

secretory azoospermia

microsurgical technique

intracytoplasmic sperm injection

Authors:

Sukhikh G.T.

Kafedra akusherstva, ginekologii, perinatologii i reproduktologii fakul'teta poslevuzovskogo professional'nogo obrazovaniia vracheĭ Moskovskoĭ meditsinskoĭ akademii im. I.M. Sechenova

Gamidov S.I.

Kafedra urologii Rossiĭskogo gosudarstvennogo meditsinskogo universiteta, Moskva

Popova A.Iu.

Nauchnyĭ tsentr akusherstva, ginekologii i perinatologii im. V.I. Kulakova Minzdravsotsrazvitiia RF, Moskva

Ovchinnikov R.I.

FGBU "Nauchnyĭ tsentr akusherstva, ginekologii i perinatologii im. akad. V.I. Kulakova" Minzdrava RF, Moskva

Shcherbakov D.V.

Otdelenie andrologii i urologii

Krasova O.M.

Kafedra urologii Rossiĭskogo natsional'nogo issledovatel'skogo meditsinskogo universiteta im. N.I. Pirogova Minzdrava Rossii

Izhbaev S.Kh.

Kafedra urologii Rossiĭskogo natsional'nogo issledovatel'skogo meditsinskogo universiteta im. N.I. Pirogova Minzdrava Rossii

Shchegolev A.I.

Institut khirurgii im. A.V. Vishnevskogo, Moskva

ORCID: 0000-0002-2111-1530

Dubova E.A.

Institut khirurgii im. A.V. Vishnevskogo, Moskva

Mishieva N.G.

FGU "Nauchnyĭ tsentr akusherstva, ginekologii i perinatologii im. akad. V.I. Kulakova" Minzdravsotsrazvitiia Rossii, Moskva

Abubakirov A.N.

FGU "Nauchnyĭ tsentr akusherstva, ginekologii i perinatologii im. akad. V.I. Kulakova" Minzdravsotsrazvitiia Rossii, Moskva

Kamaletdinov N.S.

1-e ginekologicheskoe otdelenie (reproduktsii) Nauchnogo tsentra akusherstva, ginekologii i perinatologii im. akad. V.I. Kulakova Minzdrava Rossii, Moskva

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References:

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