Component-resolved diagnosis is a new era in clinical allergology

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Mokronosova M.A.

Laboratorija klinicheskoj allergologii FGBNU «Nauchno-issledovatel'skij institut vaktsin i syvorotok im. I.I. Mechnikova», Moskva

Korovkina E.S.

NII vaktsin i syvorotok im. I.I. Mechnikova RAMN, Moskva

Component-resolved diagnosis is a new era in clinical allergology

Authors:

Mokronosova M.A., Korovkina E.S.

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Journal: Therapeutic Archive. 2013;85(10): 4‑8

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To cite this article:

Mokronosova MA, Korovkina ES. Component-resolved diagnosis is a new era in clinical allergology. Therapeutic Archive. 2013;85(10):4‑8. (In Russ.)

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Abstract:

The paper describes the fundamentals and benefits of a new allergy diagnostic technique based on recent advances in molecular biology and biotechnology. Component-resolved diagnosis allows IgE antibodies against purified molecules (individual allergen components) to be revealed. Microanalysis is made using microarrays with applied molecules (allergen components) obtained in a recombinant fashion or extracted from natural raw materials. The authors present a current classification of animal and plant allergens and show the value of component-resolved diagnosis in clinical practice, by using specific clinical examples.

Keywords:

allergy diagnosis

component resolved diagnosis

microarray

allergy diagnosis

component resolved diagnosis

microarray

Authors:

Mokronosova M.A.

Laboratorija klinicheskoj allergologii FGBNU «Nauchno-issledovatel'skij institut vaktsin i syvorotok im. I.I. Mechnikova», Moskva

Korovkina E.S.

NII vaktsin i syvorotok im. I.I. Mechnikova RAMN, Moskva

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References:

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