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Fedulova M.V.

Russian Center of Forensic Medical Expertise

Atyakshin D.A.

Peoples` Friendship University of Russia named after Patrice Lumumba

Gusarov A.A.

Russian Center of Forensic Medical Expertise

Patsap O.I.

Peoples` Friendship University of Russia named after Patrice Lumumba;
Federal Center of Brain Research and Neurotechnologies

Kostin A.A.

Peoples` Friendship University of Russia named after Patrice Lumumba

Alekhnovich A.V.

Peoples` Friendship University of Russia named after Patrice Lumumba

Prospects for the application of multiplex immunophenotyping in the practice of forensic histological examination

Authors:

Fedulova M.V., Atyakshin D.A., Gusarov A.A., Patsap O.I., Kostin A.A., Alekhnovich A.V.

More about the authors

Journal: Forensic Medical Expertise. 2026;69(1): 16‑21

DOI: 10.17116/sudmed20266901116

Read: 467 times

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Table of contents

PROSPECTS FOR THE APPLICATION OF MULTIPLEX IMMUNOPHENOTYPING IN THE PRACTICE OF FORENSIC HISTOLOGICAL EXAMINATION
PROSPECTS FOR THE APPLICATION OF MULTIPLEX IMMUNOPHENOTYPING IN THE PRACTICE OF FORENSIC HISTOLOGICAL EXAMINATION

To cite this article:

Fedulova MV, Atyakshin DA, Gusarov AA, Patsap OI, Kostin AA, Alekhnovich AV. Prospects for the application of multiplex immunophenotyping in the practice of forensic histological examination. Forensic Medical Expertise. 2026;69(1):16‑21. (In Russ.)
https://doi.org/10.17116/sudmed20266901116

Подписка 2026 Судебно-медицинская экспертиза (Forensic Medical Expertise)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

The article highlights the relevance of developing innovative technologies for the purposes of forensic pathology, describes the possibilities of the multiplex IHC method and shows some areas of its application. The tasks and problems of determining the vitality and age of injuries have been identified, which can be solved by using a multiplex IHC. The prospects of this method are revealed, which consist in the ability to formulate original hypotheses and ideas about the mechanisms of reparative regeneration, determine informative criteria of the local tissue microenvironment for detecting pathological changes, and identify new criteria for the inflammatory-reparative process in order to narrow time intervals and increase the accuracy of determining the prescription of damage in various types of trauma.

Keywords:

multiplex IHC
immunophenotyping
injuries vitality
injuries age
forensic pathology

Authors:

Fedulova M.V.

Russian Center of Forensic Medical Expertise

Atyakshin D.A.

Peoples` Friendship University of Russia named after Patrice Lumumba

Gusarov A.A.

Russian Center of Forensic Medical Expertise

Patsap O.I.

Peoples` Friendship University of Russia named after Patrice Lumumba;
Federal Center of Brain Research and Neurotechnologies

Kostin A.A.

Peoples` Friendship University of Russia named after Patrice Lumumba

Alekhnovich A.V.

Peoples` Friendship University of Russia named after Patrice Lumumba

Received:

30.06.2025

Accepted:

03.07.2025

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