The article describes the epistemological prerequisites for the use of special knowledge in the field of forensic medicine in the production of forensic graphology examinations in relation to potentially forged signatures. The authors emphasize the existence of functional unity when considering the process of cognition of such objects as a dynamic stereotype and a writing and motor skills in the performance of graphology examinations with a low level of identifying information content between such sciences as the general theory of forensic examination, methodology of forensic graphology and forensic medicine. Some provisions from earlier works of the famous Soviet and Russian scientist, forensic physician and criminologist V.V. Tomilin are given. The article substantiates the need to include the stage of an expert experiment aimed at increasing the level of cognition of a dynamic stereotype implemented through the writing and motor skills of the performer in the structure of forensic graphology examination in relation to potentially forged signatures. This article is a means of legitimization of the idea being developed by the authors on restructuring of the conclusion of the expert graphologist with the inclusion of the expert experiment stage on a methodological basis of the comprehensive use of specialized knowledge in the field of judicial graphology and forensic medicine in the research process.