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Shormanov V.K.

Kurskiĭ gosudarstvennyĭ meditsinskiĭ universitet

Pravdyuk M.F.

Republican Narcological Dispensary, Ministry of Health, Republic of North Ossetia, Vladikavkaz, Russia, 362027

Kuzovlev V.Yu.

D.I. Mendeleev Chemical and Technological University, Moscow, Russia, 125047

Shabunina N.V.

Department of Pharmaceutical, Toxicological and Аnalytical Chemistry, Kursk State Medical University, Ministry of Health of the Russia, Kursk, Russia, 305041

The distribution of 2-(dimethylamino)ethyl-(1-hydroxycyclopentyl)(phenyl)acetate in the organism of the warm-blooded animals after its intra-gastric administration

Authors:

Shormanov V.K., Pravdyuk M.F., Kuzovlev V.Yu., Shabunina N.V.

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Journal: Forensic Medical Expertise. 2018;61(2): 36‑44

DOI: 10.17116/sudmed201861236-44

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Table of contents

THE DISTRIBUTION OF 2-(DIMETHYLAMINO)ETHYL-(1-HYDROXYCYCLOPENTYL)(PHENYL)ACETATE IN THE ORGANISM OF THE WARM-BLOODED ANIMALS AFTER ITS INTRA-GASTRIC ADMINISTRATION
THE DISTRIBUTION OF 2-(DIMETHYLAMINO)ETHYL-(1-HYDROXYCYCLOPENTYL)(PHENYL)ACETATE IN THE ORGANISM OF THE WARM-BLOODED ANIMALS AFTER ITS INTRA-GASTRIC ADMINISTRATION

To cite this article:

Shormanov VK, Pravdyuk MF, Kuzovlev VYu, Shabunina NV. The distribution of 2-(dimethylamino)ethyl-(1-hydroxycyclopentyl)(phenyl)acetate in the organism of the warm-blooded animals after its intra-gastric administration. Forensic Medical Expertise. 2018;61(2):36‑44. (In Russ.)
https://doi.org/10.17116/sudmed201861236-44

Подписка 2026 Судебно-медицинская экспертиза (Forensic Medical Expertise)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

The objective of the present study was to elucidate the distribution of 2-(dimethylamino)ethyl-(1-hydroxycyclopentyl)(phenyl)acetate in the organism of the warm-blooded animals after its intra-gastric administration. The methods applied in the study included thin layer chromatography in silicagel, aci-nitroprosalt staining reaction, UV-spectrophotometry,, and GC-mass spectrometry. The identification and the quantitation of 2-(dimethylamino)ethyl-(1-hydroxycyclopentyl)(phenyl)acetate in the organs and blood of the warm-blooded animals were carried out within 20, 150, and 360 min after a single intra-gastric administration of 1300 ml of this poisonous substance. It was shown that the largest amounts of 2-(dimethylamino)ethyl-(1-hydrpxycyclopentyl)(phenyl)acetate at the above time-points were present in the tissue of the stomach and small intestine, brain, muscles, spleen, and lungs of the animals.

Keywords:

2-(dimethylamino)ethyl-(1-hydroxycyclopentyl)(phenyl)acetate
distribution in the organism
chemical toxicological analysis

Authors:

Shormanov V.K.

Kurskiĭ gosudarstvennyĭ meditsinskiĭ universitet

Pravdyuk M.F.

Republican Narcological Dispensary, Ministry of Health, Republic of North Ossetia, Vladikavkaz, Russia, 362027

Kuzovlev V.Yu.

D.I. Mendeleev Chemical and Technological University, Moscow, Russia, 125047

Shabunina N.V.

Department of Pharmaceutical, Toxicological and Аnalytical Chemistry, Kursk State Medical University, Ministry of Health of the Russia, Kursk, Russia, 305041

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References:

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  10. Görgülü Y, Ateş IÇ, Çınar RK, Sönmez MB. Cyclopentolate Use Disorder: A case report of intranasal misuse. Bağımlılık Dergisi — Journal of Dependence. 2015;16(1):39-42.
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