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Barsegian S.S.

Biuro sudebno-meditsinskoĭ ékspertizy Departamenta zdravookhraneniia Moskvy

Nikolaeva N.O.

Biuro sudebno-meditsinskoĭ ékspertizy Departamenta zdravookhraneniia Moskvy

Onishchenko M.M.

Biuro sudebno-meditsinskoĭ ékspertizy Departamenta zdravookhraneniia Moskvy

Salomatin E.M.

FGBU "Rossiĭskiĭ tsentr sudebno-meditsinskoĭ ékspertizy" Minzdravsotsrazvitiia Rossii, Moskva

Sal'nikova E.A.

Biuro sudebno-meditsinskoĭ ékspertizy Departamenta zdravookhraneniia Moskvy

The determination of clozapine for the forensic chemical study of cadaveric blood, urine, and liver with the use of high performance liquid chromatography

Authors:

Barsegian S.S., Nikolaeva N.O., Onishchenko M.M., Salomatin E.M., Sal'nikova E.A.

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Journal: Forensic Medical Expertise. 2012;55(4): 43‑47

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THE DETERMINATION OF CLOZAPINE FOR THE FORENSIC CHEMICAL STUDY OF CADAVERIC BLOOD, URINE, AND LIVER WITH THE USE OF HIGH PERFORMANCE LIQUID CHROMATOGRAPHY
THE DETERMINATION OF CLOZAPINE FOR THE FORENSIC CHEMICAL STUDY OF CADAVERIC BLOOD, URINE, AND LIVER WITH THE USE OF HIGH PERFORMANCE LIQUID CHROMATOGRAPHY

To cite this article:

Barsegian SS, Nikolaeva NO, Onishchenko MM, Salomatin EM, Sal'nikova EA. The determination of clozapine for the forensic chemical study of cadaveric blood, urine, and liver with the use of high performance liquid chromatography. Forensic Medical Expertise. 2012;55(4):43‑47. (In Russ.)

Подписка 2026 Судебно-медицинская экспертиза (Forensic Medical Expertise)
 
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Abstract:

The method for the determination of clozapine during chemical studies of cadaveric blood, urine, and liver (kidneys) has been developed based on the use of high performance liquid chromatography. Clozapine losses were estimated at 40-60% with the fractional uncertainty below 10-11% and the detection limit of 0.001 mg%. An algorithm for the estimation of the quality of clozapine isolation and the results of analysis of individual samples is proposed.

Keywords:

clozapine
high performance liquid chromatography

Authors:

Barsegian S.S.

Biuro sudebno-meditsinskoĭ ékspertizy Departamenta zdravookhraneniia Moskvy

Nikolaeva N.O.

Biuro sudebno-meditsinskoĭ ékspertizy Departamenta zdravookhraneniia Moskvy

Onishchenko M.M.

Biuro sudebno-meditsinskoĭ ékspertizy Departamenta zdravookhraneniia Moskvy

Salomatin E.M.

FGBU "Rossiĭskiĭ tsentr sudebno-meditsinskoĭ ékspertizy" Minzdravsotsrazvitiia Rossii, Moskva

Sal'nikova E.A.

Biuro sudebno-meditsinskoĭ ékspertizy Departamenta zdravookhraneniia Moskvy

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References:

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