Sjogren’s disease/syndrome in combination with autoimmune liver damage. 20-years observation

Gaiduk I.V.

Moscow State Medical and Dental University named after A.I. Yevdokimov

Vasiliev V.I.

«RHEUMOCENTER for the Treatment of Joints and Heart» Ltd

Fakhrislamova L.R.

Moscow State Medical and Dental University named after A.I. Yevdokimov

Panin A.M.

Evdokimov Moscow State University of Medicine and Dentistry

Palshina S.G.

«RHEUMOCENTER for the Treatment of Joints and Heart» Ltd

Rodionova E.B.

ANPO «Sjogren-No»

Sjogren’s disease/syndrome in combination with autoimmune liver damage. 20-years observation

Authors:

Gaiduk I.V., Vasiliev V.I., Fakhrislamova L.R., Panin A.M., Palshina S.G., Rodionova E.B.

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Journal: Stomatology. 2021;100(6): 108‑114

DOI: 10.17116/stomat2021100061108

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To cite this article:

Gaiduk IV, Vasiliev VI, Fakhrislamova LR, Panin AM, Palshina SG, Rodionova EB. Sjogren’s disease/syndrome in combination with autoimmune liver damage. 20-years observation. Stomatology. 2021;100(6):108‑114. (In Russ.)
https://doi.org/10.17116/stomat2021100061108

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Sjogren’s disease (BS) is a systemic autoimmune disease, the main symptoms of which are associated with dry eyes, mouth, skin, respiratory and gastrointestinal tract, etc., but there are a large number of extra-vascular symptoms that can accompany this disease: weakness, swelling of the lymph nodes, respiratory failure, pain and swelling of the joints, rash, dysphagia, gastro-esophageal reflux, lymphoma, etc. In addition, the etiology of this disease remains unknown, and the pathogenesis is partially studied. The diagnosis of Sjogren’s disease is complicated by a variety of clinical manifestations, as well as subacute and chronic variants of the course of the disease, in addition, the diagnostic criteria are periodically changed. It is recommended to adhere to the domestic diagnostic criteria considering the presence of laboratory signs of an autoimmune disease. The article presents a clinical observation of a patient with the development of the main symptoms and signs of BS and autoimmune hepatitis for 20 years. Recurrent mumps or chronic bilateral enlargement of the parotid salivary glands may be the first symptom of Sjogren’s disease, which is recommended to extend the examination in order to identify other, sometimes latent signs of the disease.

Keywords:

Sjogren’s disease

Sjogren’s syndrome

sialography

parenchymal mumps

primary biliary cirrhosis

autoimmune hepatitis

antinuclear factor

gamma-globulin protein fraction

anti-Ro/SSA and anti-La/SSB anti-nuclear antibodies

Authors:

Gaiduk I.V.

Moscow State Medical and Dental University named after A.I. Yevdokimov

Vasiliev V.I.

«RHEUMOCENTER for the Treatment of Joints and Heart» Ltd

Fakhrislamova L.R.

Moscow State Medical and Dental University named after A.I. Yevdokimov

Panin A.M.

Evdokimov Moscow State University of Medicine and Dentistry

Palshina S.G.

«RHEUMOCENTER for the Treatment of Joints and Heart» Ltd

Rodionova E.B.

ANPO «Sjogren-No»

Received:

22.04.2021

Accepted:

06.09.2021

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