Flowmetrical features of the postoperative wound process in drug addicted patients with chronic odontogenic osteomyelitis of the jaws when using different surgical approaches

Bezrukov S.G.; Anosov M.S.; Bezrukov G.S.; Sayenko V.L.

doi:https://doi.org/10.17116/stomat20199806139

Bezrukov S.G.

Medical Academy named after S.I. Georgievsky of Crimean Federal University named after V.I. Vernadsky, Simferopol, Republic of Crimea, Russia

Anosov M.S.

Medical Academy named after S.I. Georgievsky of Crimean Federal University named after V.I. Vernadsky, Simferopol, Republic of Crimea, Russia

Bezrukov G.S.

Medical Academy named after S.I. Georgievsky of Crimean Federal University named after V.I. Vernadsky, Simferopol, Republic of Crimea, Russia

Sayenko V.L.

Medical Academy named after S.I. Georgievsky of Crimean Federal University named after V.I. Vernadsky, Simferopol, Republic of Crimea, Russia

Flowmetrical features of the postoperative wound process in drug addicted patients with chronic odontogenic osteomyelitis of the jaws when using different surgical approaches

Authors:

Bezrukov S.G., Anosov M.S., Bezrukov G.S., Sayenko V.L.

More about the authors

Journal: Stomatology. 2019;98(6): 39‑43

DOI: 10.17116/stomat20199806139

Read: 941 times

Download PDF (RU)

Contact the author

Table of contents

To cite this article:

Bezrukov SG, Anosov MS, Bezrukov GS, Sayenko VL. Flowmetrical features of the postoperative wound process in drug addicted patients with chronic odontogenic osteomyelitis of the jaws when using different surgical approaches. Stomatology. 2019;98(6):39‑43. (In Russ.)
https://doi.org/10.17116/stomat20199806139

Подписка 2026 Стоматология (Stomatology)

Использование инфографики авторами научных работ

Close metadata

Recommended articles:

Modern concepts of managing patients with thyrotoxic heart. Russian Journal of Preventive Medicine. 2024;(10):125-130

Abstract:

The aim of the work was to study changes in local microhemodynamic indices in drug addicted patients in the course of the treatment of chronic odontogenic osteomyelitis. Assessment of tissue blood flow in gingival mucosa in patients with chronic osteomyelitis was performed using Laser doppler flowmetry. All patients were divided into two groups, namely treatment (n=21) and control (n=19). Sequestrectomy was performed to the patients from the treatment group with a bone defect closed with a concomitant use of PRP gel and FRP membranes. The same surgery was performed to patients from control group with a bone defect closed with iodoform tampon. During the study it was revealed that sequestrectomy with use of PRP gel and FRP membranes leads to rapid decrease in local postoperative inflammatory reactions, improvement of venous outflow and better functioning of microvessels endothelium and general optimization of the tissue healing process in drug addicted patients with chronic odontogenic osteomyelitis.

Keywords:

odontogenic osteomyelitis of the jaws of drug addicts

complex treatment

PRP gel and FRP membranes

flowmetry

Authors:

Bezrukov S.G.

Medical Academy named after S.I. Georgievsky of Crimean Federal University named after V.I. Vernadsky, Simferopol, Republic of Crimea, Russia

Anosov M.S.

Medical Academy named after S.I. Georgievsky of Crimean Federal University named after V.I. Vernadsky, Simferopol, Republic of Crimea, Russia

Bezrukov G.S.

Medical Academy named after S.I. Georgievsky of Crimean Federal University named after V.I. Vernadsky, Simferopol, Republic of Crimea, Russia

Sayenko V.L.

Medical Academy named after S.I. Georgievsky of Crimean Federal University named after V.I. Vernadsky, Simferopol, Republic of Crimea, Russia

Close metadata

References:

Basin EM, Kirillov YuA, Medvedev YuA, Dokina EK. Clinico-morphological charecterists of jaw osteonecrosis among drug addicts. Rossiyskiy stomatologicheskiy zhurnal. 2015;19(2):14-17. (In Russ.)
Bezrukov SG, Sayenko VL, Anosov MS. Clinical cure and flowmetric rates of drug-addicted patients with osteomyelitis of the jaws. Tavricheskiy mediko-biologicheskiy vestnik. 2017;20(4):26-32. (In Russ.)
Akopyan KA. The state of oral cavity at drug addict patients with jaw osteonecrosis who use the drug «crocodile» (desomorphine). Vestnik stomatologii i chelyustno-litsevoy khirurgii. 2012;1:16-19. (In Russ.)
Bezrukov SG, Sayenko VL, Anosov MS. Clinical and laboratory assessment of treatment outcome of drug-addicted patients with osteomyelitis of the jaws. Krymskiy terapevticheskiy zhurnal. 2016;4(31):28-35. (In Russ.)
Medvedev YuA, Basin EM, Milyukova DYu, Fialko PV. Surgical treatment of midface jaw osteonecrosis. Rossiyskiy stomatologicheskiy zhurnal. 2018;22(2):92-95. (In Russ.)
Basin EM, Medvedev YuA. Toxic phosphorus osteonecrosis of facial bones among drug addicts to desomorphine and pervitin. Stomatologiya. 2015;94(2):53-57. (In Russ.) https://doi.org/10.17116/stomat201594367-69
Dunford JE, Thompson K, Coxon FP, et al. Structure-activity relationships for inhibition of farnesyl diphosphate synthase in vitro and inhibition of bone resorption in vivo by nitrogen-containing bisphosphonates. J Pharmacol Exper Ther. 2001;296(2):235-242.
Lazernaya dopplerovskaya floumetriya mikrotsirkulyatsii krovi. Rukovodstvo dlya vrachey. Krupatkina A.I., Sidorova V.V., eds. M.: Meditsina; 2005. (In Russ.)
Anosov MS, Bezrukov SG, Sayenko VL. Sposob lecheniya khronicheskogo odontogennogo osteomiyelita u narkozavisimykh bol’nykh. The Russian Federation patent for an invention №2599874/20.10.2016. Journ. №29. Active hyperlink on February 13, 2019. (In Russ.) http://www.fips.ru/Archive4/PAT/2016FULL/2016.10.20/DOC/RUNWC2/000/000/002/599/874/DOCCLAIM.PDF
Khirurgicheskaya stomatologiya i chelyustno-litsevaya khirurgiya. Natsional’noye rukovodstvo. Kulakov AA, Robustova TG, Nerobeev AI, eds. M.: GEOTAR-Media; 2010. (In Russ.)
Maghsoudi O, Ranjbar R, Mirjalili SH, Fasihi-Ramandi M. Inhibitory Activities of Platelet-Rich and Platelet-Poor Plasma on the Growth of Pathogenic Bacteria. Iranian J Pathol. 2017;12(1):79-87.
Chen NF, Sung CS, Wen ZH, Chen CH, Feng CW, Hung HC, Yang SN, Tsui KH, Chen WF. Therapeutic Effect of Platelet-Rich Plasma in Rat Spinal Cord Injuries. Front Neuroscie. 2018;23(12):252. https://doi.org/10.3389/fnins.2018.00252
Zhang XL, Shi KQ, Jia PT, Jiang LH, Liu YH, Chen X, Zhou ZY, Li YX, Wang LS. Effects of platelet-rich plasma on angiogenesis and osteogenesis-associated factors in rabbits with avascular necrosis of the femoral head. Eur Rev Med Pharmacol Scie. 2018;22(7):2143-2152. https://doi.org/10.26355/eurrev_201804_14748
Panteleev MA, Sveshnikova AN. Platelets and hemostasis. Onkogematologiya. 2014;2:65-73. (In Russ.)
Li X, Hou J, Wu B, Chen T, Luo A. Effects of platelet-rich plasma and cell coculture on angiogenesis in human dental pulp stem cells and endothelial progenitor cells. J Endodont. 2014;40(11):1810-1814. https://doi.org/10.1016/j.joen.2014.07.022
Santos S, Sigurjonsson OE, Custodio C, Mano JFCDL. Blood plasma derivatives for tissue engineering and regenerative medicine therapies. Tissue Engineering Part B: Reviews. 2018;24(6):454-462. https://doi.org/10.1089/ten.TEB.2018.0008