Local immune and oxidative status in exacerbated chronic apical periodontitis

Konoplya A.I.; Goldobin D.D.; Loktionov A.L.

doi:https://doi.org/10.17116/stomat201796326-29

Konoplya A.I.

Department of Biochemistry, Kursk State Medical University, Ministry of Health of Russia, Kursk, Russia

Goldobin D.D.

Kursk State Medical University, Kursk, Russia

Loktionov A.L.

Kursk State Medical University, Kursk, Russia

Local immune and oxidative status in exacerbated chronic apical periodontitis

Authors:

Konoplya A.I., Goldobin D.D., Loktionov A.L.

More about the authors

Journal: Stomatology. 2017;96(3): 26‑29

DOI: 10.17116/stomat201796326-29

Read: 1166 times

Download PDF (RU)

Contact the author

Table of contents

To cite this article:

Konoplya AI, Goldobin DD, Loktionov AL. Local immune and oxidative status in exacerbated chronic apical periodontitis. Stomatology. 2017;96(3):26‑29. (In Russ.)
https://doi.org/10.17116/stomat201796326-29

Подписка 2026 Стоматология (Stomatology)

Использование инфографики авторами научных работ

Close metadata

Abstract:

The aim of the study was to define local immune and oxidative changes in patients with exacerbated chronic apical periodontitis. These changes were assessed in saliva of 67 patients with the mean age of 31±2.5 before and after treatment. The study revealed disturbances in cytokines and complement system balance and activation of lipids peroxidation. Combination of Gepon or Vobenzim with Essentiale forte H and Kaskatol proved to be the most effective for correction of this imbalance.

Keywords:

chronic apical periodontitis

immune and oxidative disturbances

Authors:

Konoplya A.I.

Department of Biochemistry, Kursk State Medical University, Ministry of Health of Russia, Kursk, Russia

Goldobin D.D.

Kursk State Medical University, Kursk, Russia

Loktionov A.L.

Kursk State Medical University, Kursk, Russia

Close metadata

References:

Afanas'ev SS, Aleshkin VA, Voropaeva EA, Afanas'ev MS, Slobodenyuk VV, Karaulov AV. Mikrobiotsenozy otkrytykh polostey i mukozal'nyy immunitet [Microbiocenoses of open cavities and mukozalny immunity]. Effektivnaya farmakoterapiya. 2013;27:6-11. (In Russ.).
Berezin KA. Gistokhimicheskie osobennosti razvitiya patologicheskogo protsessa pri khronicheskikh formakh periodontita [Histochemical features of development of pathological process at chronic forms of a periodontitis]. Parodontologiya. 2014;19(3):63-67. (In Russ.).
Gavrilov VB, Mishkorudnaya Mi. Spektrofotometricheskoe opredelenie soderzhaniya gidroperekisey lipidov v plazme krovi [Spectrum photometric definition of the maintenance of hydroperoxides of lipids in a blood plasma]. Lab. delo. 1983;3:33-36. (In Russ.).
Dedova LN, Lapitskaya AV. Bystroprogressiruyushchiy periodontit: metody lecheniya (chasf 2) [The fast-progressing periodontitis: methods of treatment (part 2)]. Minsk: Stomatolog; 2014. (In Russ.).
Zharkova ОA. Immunologicheskie i mikrobiologicheskie aspekty khronicheskikh periodontitov [Immunologic and microbiological aspects of a chronic periodontitis]. Vestnik VGMU. 2006;5(3):1-11. (In Russ.).
Kostyuk VA, Potapovich AI, Kovaleva ZhI. Prostoy i chuvstvitel'nyy metod opredeleniya superoksiddismutazy, osnovannyy na reaktsii okisleniya kvertsetina [The simple and sensitive method of definition of a superoksiddismutaza based on reaction of oxidation of Quercetinum]. Voprosy meditsinskoy khimii. 1990;2:88-91. (In Russ.).
Lazarev AI, Brovkina IL, Gavrilyuk VP, Konoplya AI, Losenok SA, Prokopenko LG, Rybnikov VN, Siplivyy GV. Eritrotsitzavisimye effekty lekarstvennykh i fizioterapevticheskikh sredstv [Erythrocytes dependent effects of medicinal and physiotherapeutic agents]. Pod red. Prokopenko L.G. Kursk: KGMU; 2008. (In Russ.).
Lazareva GA, Brovkina IL, Lazarev AI, Prokopenko LG, Konoplya AI, Denesyuk TA. Immunometabolicheskie effekty regulyatorov energeticheskogo obmena pri narushenii gomeostaza [Immunometabolic effects of regulators of energy balance at disturbance of a homeostasis]. Kursk: Izd-vo KGMU; 2006. (In Russ.).
Lunev MA, Loktionov AL, Konoplya AI. Korrektsiya narusheniy sistemy komplementa na sistemnom i lokal'nom urovne pri odontogennom osteomielite chelyustnolitsevoy oblasti [Correction of disturbances of system of a complement at the systemic and local level at a odontogenous osteomyelitis of maxillofacial area]. Vestnik novykh meditsinskikh tekhnologiy. Elektronnoe izdanie. 2013;1:37. (In Russ.).
Uspenskaya MN, Konoplya AI, Loktionov AL. Korrektsiya immunometabolicheskikh narusheniy pri khronicheskom generalizovannom parodontite s ispol'zovaniem Gepona, Gipoksena i Fosfogliva Forte [Correction of immunometabolic disturbances at a chronic generalized periodontal disease with use Gepona, Gipoksen and Fosfogliv Forte]. Sistemnyy analiz i upravlenie v biomeditsinskikh sistemakh. 2012;11(4):908-913. (In Russ.).