Relevance. The present-day situation is characterized by the increasingly greater number of the patients presenting with perforative forms of odontogenic sinusitis. In 41,2% - 91,7% of the cases, perforations of maxillary sinuses are considered to be the predisposing factors for the development of sinusitis [1, 2]. One of the promising approaches to the management of the patients with this pathology is the intraoperative and postoperative application of the innovative phytopreparations during the combined surgical treatment as well as their application in the postoperative period [3.4]. Aim. The objective of the present study was to increase the effectiveness of the surgical treatment of the patients presenting with chronic odontogenic maxillary sinusitis complicated by the oronasal communications and the prophylaxis of the potential complications. Material and methods. A total of 24 patients presenting with chronic odontogenic maxillary sinusitis complicated by the communications in the region of the extracted teeth of the upper jaw were admitted to our clinic of maxillofacial surgery during the period from 2012 to 2014. The patients were randomly divided into two groups, the control one in which they were treated by conventional sparing sinusotomy and the study group in which the patients were treated by sinusotomy using our original method with the use of phytopreparations. Results and discussion. The study has demonstrated that 45% of the patients treated by conventional sparing sinusotomy developed postoperative complications of different severity. It proved possible to avoid these complications by combining the surgical treatment by means of modified sinusotomy with the application of the innovative phytopreparations. This result was confirmed by clinical observations and immunological studies. Conclusion. The proposed method for the plastic correction of the oroantral communications makes it possible to reconstruct the maxillary sinus architectonics, prolong the beneficial influence of medication in the region of surgical intervention, and thereby to reduce the risk of complications and increase the general effectiveness of the treatment.