Study of the association of genetic polymorphisms with the consumption of some nutrients

Baturin A.K.

Federal Research Center of Nutrition and Biotechnology, Moscow, Russia

Sorokina E.Yu.

Federal Research Center of Nutrition and Biotechnology, Moscow, Russia

Keshabyants E.E.

Federal Research Center of Nutrition and Biotechnology, Moscow, Russia

Kobelkova I.V.

Federal Research Center of Nutrition and Biotechnology, Moscow, Russia

Study of the association of genetic polymorphisms with the consumption of some nutrients

Authors:

Baturin A.K., Sorokina E.Yu., Keshabyants E.E., Kobelkova I.V.

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Journal: Russian Journal of Preventive Medicine. 2018;21(6): 36‑41

DOI: 10.17116/profmed20182106136

Downloaded: 31

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To cite this article:

Baturin AK, Sorokina EYu, Keshabyants EE, Kobelkova IV. Study of the association of genetic polymorphisms with the consumption of some nutrients. Russian Journal of Preventive Medicine. 2018;21(6):36‑41. (In Russ.)
https://doi.org/10.17116/profmed20182106136

Подписка 2025-2 (Russian Journal of Preventive Medicine)

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Thanks to the active introduction of molecular genetic technologies in healthcare practice, it became known that a genetic factor plays a significant role in human eating behavior. The paper presents the results of studies of an association between FTO rs9939609, ADRB3 rs4994, UCP2 rs659366, and KCNJ11 rs5219 polymorphisms in the population of the Arctic zone (Yamal-Nenets Autonomous Area) of the Russian Federation with the levels of fat, saturated fatty acids (SFAs), carbohydrates, and added sugar in the diet. The studies confirmed the presence of genetic traits in the inhabitants of this region and revealed the statistically significant association of the A allele of FTO rs9939609 polymorphism with the high content of SFAs in the diet, which is characteristic only for women. There were no statistical significant associations between FTO rs9939609, ADRB3 rs4994, UCP2 rs659366, KCNJ11 rs5219 polymorphisms and the levels of fat, carbohydrates, and added sugars in the diet of the examinees from the Arctic zone of the Russian Federation.

Keywords:

actual nutrition

FTO rs993609 polymorphism

UCP2 rs659366 polymorphism

ADRB3 rs5219 polymorphism

KCNJ11 rs5219 polymorphism

Arctic Zone

Yamal-Nenets Autonomous Area

Authors:

Baturin A.K.

Federal Research Center of Nutrition and Biotechnology, Moscow, Russia

Sorokina E.Yu.

Federal Research Center of Nutrition and Biotechnology, Moscow, Russia

Keshabyants E.E.

Federal Research Center of Nutrition and Biotechnology, Moscow, Russia

Kobelkova I.V.

Federal Research Center of Nutrition and Biotechnology, Moscow, Russia

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