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Kirienko K.V.

LLC «ECO center»

Apryshko V.P.

Klinika "Al'tra Vita", Moskva, Rossiĭskaia Federatsiia

Iakovenko S.A.

Klinika "Al'tra Vita", Moskva, Rossiĭskaia Federatsiia

Assisted hatching (literature review)

Authors:

Kirienko K.V., Apryshko V.P., Iakovenko S.A.

More about the authors

Journal: Russian Journal of Human Reproduction. 2019;25(4): 89‑101

DOI: 10.17116/repro20192504189

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Table of contents

ASSISTED HATCHING (LITERATURE REVIEW)
ASSISTED HATCHING (LITERATURE REVIEW)

To cite this article:

Kirienko KV, Apryshko VP, Iakovenko SA. Assisted hatching (literature review). Russian Journal of Human Reproduction. 2019;25(4):89‑101. (In Russ.)
https://doi.org/10.17116/repro20192504189

Подписка 2025-2 (Russian Journal of Human Reproduction)
 
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The complex of manipulations, such as thinning, breaking the integrity or removing the zona pellucida (ZP), in order to facilitate the hatching of the embryo from the ZP is called assisted hatching (AH). This procedure was introduced into embryological practice in order to increase embryonic implantation, and in the end, to improve the effectiveness of ART. However, the weak evidence base and lack of biological justification raises many doubts about the routine use of AH. This paper presents a systematic analysis of the clinical outcomes of IVF cycles after applying various AH options on fresh and cryopreserved/thawed embryos at different stages of development in patients of different groups. This work will be of interest to embryologists and reproductive doctors in connection with the rather wide use of AH in the practice of IVF clinics.

Keywords:

zona pellucida
embryo cultivation
embryo hatching
assisted hatching
implantation

Authors:

Kirienko K.V.

LLC «ECO center»

Apryshko V.P.

Klinika "Al'tra Vita", Moskva, Rossiĭskaia Federatsiia

Iakovenko S.A.

Klinika "Al'tra Vita", Moskva, Rossiĭskaia Federatsiia

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